Search Results - "KARP, C"

Topical interferon alpha 2b eye-drops for treatment of ocular surface squamous neoplasia: a dose comparison study by Galor, A, Karp, C L, Chhabra, S, Barnes, S, Alfonso, E C

“…BACKGROUND/AIMS To compare the effectiveness and side-effect profile of two doses of interferon alpha2b (IFNalpha2b) eye-drops (1 million international units…”
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Defects in mucosal immunity leading to ulcerative colitis by Targan, Stephan R., Karp, Loren C.

“…Evidence accumulated over the last decade demonstrates that what we call ‘ulcerative colitis’ is actually a heterogeneous group of diseases resulting from…”
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New insights into innate immune mechanisms underlying allergenicity by Wills-Karp, M, Nathan, A, Page, K, Karp, C L

“…Allergic diseases, which have reached epidemic proportions, are caused by inappropriate immune responses to a relatively small number of environmental…”
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Distinct Tlr4-expressing cell compartments control neutrophilic and eosinophilic airway inflammation by McAlees, J W, Whitehead, G S, Harley, I TW, Cappelletti, M, Rewerts, C L, Holdcroft, A M, Divanovic, S, Wills-Karp, M, Finkelman, F D, Karp, C L, Cook, D N

“…Allergic asthma is a chronic, inflammatory lung disease. Some forms of allergic asthma are characterized by T helper type 2 (Th2)-driven eosinophilia, whereas…”
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Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology by Shirey, K A, Lai, W, Pletneva, L M, Karp, C L, Divanovic, S, Blanco, J C G, Vogel, S N

“…Resolution of severe Respiratory Syncytial Virus (RSV)-induced bronchiolitis is mediated by alternatively activated macrophages (AA-Mφ) that counteract…”
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Therapeutic starvation and autophagy in prostate cancer: A new paradigm for targeting metabolism in cancer therapy by DiPaola, Robert S., Dvorzhinski, Dmitri, Thalasila, Anu, Garikapaty, Venkata, Doram, Donyell, May, Michael, Bray, K., Mathew, Robin, Beaudoin, Brian, Karp, C., Stein, Mark, Foran, David J., White, Eileen

“…BACKGROUND Autophagy is a starvation induced cellular process of self‐digestion that allows cells to degrade cytoplasmic contents. The understanding of…”
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Interleukin-13: Central Mediator of Allergic Asthma by Wills-Karp, Marsha, Luyimbazi, Jackie, Xu, Xueying, Schofield, Brian, Neben, Tamlyn Y., Karp, Christopher L., Donaldson, Debra D.

“…The worldwide incidence, morbidity, and mortality of allergic asthma are increasing. The pathophysiological features of allergic asthma are thought to result…”
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Leptin regulates proinflammatory immune responses by Loffreda, S. (John Hopkins University, Baltimore, MD.), Yang, S.Q, Lin, H.Z, Karp, C.L, Brengman, M.L, Wang, D.J, Klein, A.S, Bulkley, G.B, Bao, C, Noble, P.W

“…Obesity is associated with an increased incidence of infection, diabetes, and cardiovascular disease, which together account for most obesity-related morbidity…”
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A Common Single Nucleotide Polymorphism in the CD14 Promoter Decreases the Affinity of Sp Protein Binding and Enhances Transcriptional Activity by LeVan, Tricia D, Bloom, John W, Bailey, Thomas J, Karp, Christopher L, Halonen, Marilyn, Martinez, Fernando D, Vercelli, Donata

“…CD14 is a pattern recognition receptor that plays a central role in innate immunity through recognition of bacterial lipoglycans, primarily LPS. Recently, our…”
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Marker antibody expression stratifies Crohn's disease into immunologically homogeneous subgroups with distinct clinical characteristics by Vasiliauskas, E A, Kam, L Y, Karp, L C, Gaiennie, J, Yang, H, Targan, S R

“…BACKGROUND Perinuclear antineutrophil cytoplasmic antibodies (pANCA) have been detected in a clinically distinct Crohn's disease subpopulation. Antibodies…”
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P56 SURVIVAL BENEFIT OF BIRTAMIMAB IN MAYO STAGE IV AL AMYLOIDOSIS IN THE PHASE 3 VITAL STUDY WAS CONSISTENT ACROSS ALL KEY BASELINE VARIABLES by Gertz, M., Cohen, A., Comenzo, R., Kastritis, E., Landau, H., Libby, E., Liedtke, M., Sanchorawala, V., Schönland, S., Wechalekar, A., Ando, Y., Koh, Y., Zonder, J., Palladini, G., Nie, C., Karp, C., Jin, Y., Conrad, A., Kinney, G., Merlini, G.

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Mechanism of Suppression of Cell-Mediated Immunity by Measles Virus by Karp, Christopher L., Wysocka, Maria, Wahl, Larry M., Ahearn, Joseph M., Cuomo, Peter J., Sherry, Barbara, Trinchieri, Giorgio, Griffin, Diane E.

“…The mechanisms underlying the profound suppression of cell-mediated immunity (CMI) accompanying measles are unclear. Interleukin-12 (IL-12), derived…”
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The germless theory of allergic disease: revisiting the hygiene hypothesis by Wills-Karp, Marsha, Karp, Christopher L, Santeliz, Joanna

“…Rising rates of allergic disease accompany the healthier benefits of a contemporary westernized lifestyle, such as low infant mortality. It is likely that…”
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Trusted to Learn: a Qualitative Study of Clerkship Students’ Perspectives on Trust in the Clinical Learning Environment by Karp, Nathan C., Hauer, Karen E., Sheu, Leslie

“…Background Trust informs supervision decisions in medical training. Factors that influence trust differ depending on learners’ and supervisors’ level. Research…”
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HRPAP20: a novel calmodulin-binding protein that increases breast cancer cell invasion by KARP, C. M, SHUKLA, M. N, BUCKLEY, D. J, BUCKLEY, A. R

“…We previously reported the identification of HRPAP20 (hormone-regulated proliferation-associated protein 20), a novel hormone-regulated,…”
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Inhibition of IL-12 production by thalidomide by Moller, DR, Wysocka, M, Greenlee, BM, Ma, X, Wahl, L, Flockhart, DA, Trinchieri, G, Karp, CL

“…The immunomodulatory properties of thalidomide are currently being exploited therapeutically in conditions as diverse as erythema nodosum leprosum, chronic…”
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IL-12 Suppression During Experimental Endotoxin Tolerance: Dendritic Cell Loss and Macrophage Hyporesponsiveness by Wysocka, Maria, Robertson, Susan, Riemann, Helge, Caamano, Jorge, Hunter, Christopher, Mackiewicz, Agnieszka, Montaner, Luis J, Trinchieri, Giorgio, Karp, Christopher L

“…Endotoxin tolerance, the transient, secondary down-regulation of a subset of endotoxin-driven responses after exposure to bacterial products, is thought to be…”
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Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice by Gavett, S H, O'Hearn, D J, Karp, C L, Patel, E A, Schofield, B H, Finkelman, F D, Wills-Karp, M

“…The functional role of interleukin (IL)-4 in the development of airway hyperresponsiveness (AHR) and pulmonary eosinophilia in response to sensitization and…”
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Perilesional and topical interferon alfa-2b for conjunctival and corneal neoplasia by Vann, R R, Karp, C L

“…To evaluate the role of combined subconjunctival and topical interferon alfa-2b (IFN alpha 2b) in the treatment of conjunctival and corneal intraepithelial…”
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Coinfection with HIV and Tropical Infectious Diseases. I. Protozoal Pathogens by Mayer, Kenneth H., Karp, Christopher L., Auwaerter, Paul G.

“…The brunt of the human immunodeficiency virus (HIV) pandemic has been borne disproportionately by resource-poor regions of the world, where tropical infectious…”
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