Search Results - "KAROL, Meryl H"
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Current State of the Science: Health Effects and Indoor Environmental Quality
Published in Environmental health perspectives (01-06-2007)“…Our understanding of the relationship between human health and the indoor environment continues to evolve. Previous research on health and indoor environments…”
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Journal Article -
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Identification of human lung and skin proteins conjugated with hexamethylene diisocyanate in vitro and in vivo
Published in American journal of respiratory and critical care medicine (01-12-2000)“…Diisocyanates are asthma-causing chemicals used in the commercial production of polyurethane. We have previously shown that human lung epithelial cell proteins…”
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Conference Proceeding Journal Article -
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Role of Tumor Necrosis Factor in Toluene Diisocyanate Asthma
Published in American journal of respiratory cell and molecular biology (01-10-2002)“…Nearly 9 million workers are exposed to chemical agents associated with occupational asthma, with isocyanates representing the chemical class most responsible…”
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Improving Indoor Environmental Quality for Public Health: Impediments and Policy Recommendations
Published in Environmental health perspectives (01-06-2007)“…Background: People in modern societies spend more than 90% of their time indoors. Hence, indoor environmental quality (IEQ) has a significant impact on public…”
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How Environmental Agents Influence the Aging Process
Published in Biomolecules & therapeutics (2009)“…Aging is a multifaceted biological process that affects all organs and organ systems of the body. This review provides an up-to-date analysis of this highly…”
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Formation, Solvolysis, and Transcarbamoylation Reactions of Bis(S-glutathionyl) Adducts of 2,4- and 2,6-Diisocyanatotoluene
Published in Chemical research in toxicology (01-04-1997)“…During our ongoing studies of the reactions of toluene diisocyanate (2,4- and 2,6-diisocyanatotoluene, TDI) in vivo, it became apparent that reactive form(s)…”
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How Environmental Agents Influence the Aging Process
Published in Biomolecules & therapeutics (30-04-2009)“…Aging is a multifaceted biological process that affects all organs and organ systems of the body. This review provides an up-to-date analysis of this highly…”
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Journal Article -
8
Diisocyanate asthma: clinical aspects and immunopathogenesis
Published in International Immunopharmacology (01-02-2002)“…Diisocyanates, highly reactive chemicals used in the production of polyurethanes, are currently the most frequently reported cause of chemically induced…”
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Book Review Journal Article -
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Can Mold Contamination of Homes Be Regulated? Lessons Learned from Radon and Lead Policies
Published in Environmental science & technology (15-07-2007)“…Increasingly, airborne mold in home environments has been linked with asthma exacerbation and other respiratory diseases in both children and adults. This…”
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Conjugation of haptens
Published in Methods in molecular medicine (2008)“…Many naturally occurring proteins, peptides, carbohydrates, nucleic acids, and lipids, as well as synthetic peptides, are successful immunogens. To elicit an…”
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Toluene diisocyanate protein adducts in the bronchoalveolar lavage of guinea pigs exposed to vapors of the chemical
Published in Chemical research in toxicology (01-11-1993)“…To investigate the process of toluene diisocyanate (TDI) sensitization, studies were conducted to identify TDI-protein adducts in the bronchoalveolar lavage…”
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How Environmental Agents Influence the Aging Process
Published in Biomolecules & therapeutics (30-04-2009)Get full text
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13
IMMUNOTOXICOLOGY: Past, Present, and Future
Published in Inhalation toxicology (01-06-1999)“…The goal of immunotoxicology is the detection and quantification of alterations in the immune system resulting from exposure to biological or chemical agents…”
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Rapid Reduction of Intracellular Glutathione in Human Bronchial Epithelial Cells Exposed to Occupational Levels of Toluene Diisocyanate
Published in Toxicological sciences (01-04-2001)“…Toluene diisocyanate (TDI) is a recognized chemical asthmogen, yet the mechanism of this toxicity and the molecular reactions involved have not been…”
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Journal Article -
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Respiratory allergy: what are the uncertainties?
Published in Toxicology (Amsterdam) (27-12-2002)“…The prevalence of asthma is increasing worldwide. The increase has been found for both sexes, for all races and age groups. The factors responsible are…”
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Journal Article Conference Proceeding -
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A MOUSE MODEL FOR STUDY OF LOCALIZED TOLUENE DIISOCYANATE ADDUCTS FOLLOWING INTRABRONCHIAL ADMINISTRATION OF THE CHEMICAL: INFLAMMATION AND ANTIBODY PRODUCTION
Published in Inhalation toxicology (1998)“…Intranasal and intratracheal administration of chemicals are alternative routes to inhalation in some immunologic and toxicologic studies. Selection of an…”
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The potential adverse health effects of dental amalgam
Published in Toxicological reviews (2005)“…There is significant public concern about the potential health effects of exposure to mercury vapour (Hg(0)) released from dental amalgam restorations. The…”
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Journal Article -
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Intracellular S-Glutathionyl Adducts in Murine Lung and Human Bronchoepithelial Cells after Exposure to Diisocyanatotoluene
Published in Chemical research in toxicology (01-10-1999)“…Diisocyanatotoluene (toluene diisocyanate, TDI), a 4:1 mixture of 2,4- and 2,6-isomers used in the preparation of polyurethanes, causes occupational asthma by…”
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Bonding and transfer: do epithelial conjugates have a role in chemical asthma?
Published in Clinical and experimental allergy (01-03-2001)Get full text
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PREDICTION OF THE METABOLISM AND TOXICOLOGICAL PROFILES OF GASOLINE OXYGENATES
Published in Inhalation toxicology (1997)“…Methyl tert -butyl ether (MTBE), ethyl tert -butyl ether (ETBE), tert -amyl methyl ether (TAME), and diisopropyl ether (DIPE) were evaluated with…”
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