Search Results - "KARBOWNIK, MALGORZATA"

Iodine as a potential endocrine disruptor—a role of oxidative stress by Karbownik-Lewińska, Małgorzata, Stępniak, Jan, Iwan, Paulina, Lewiński, Andrzej

“…Purpose Iodine is an essential micronutrient required for thyroid hormone biosynthesis. However, overtreatment with iodine can unfavorably affect thyroid…”
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Impact of visceral adipose tissue on longevity and metabolic health: a comparative study of gene expression in perirenal and epididymal fat of Ames dwarf mice by Zaczek, Agnieszka, Lewiński, Andrzej, Karbownik-Lewińska, Małgorzata, Lehoczki, Andrea, Gesing, Adam

“…Emerging research underscores the pivotal role of adipose tissue in regulating systemic aging processes, particularly when viewed through the lens of the…”
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Potential Risk Factors for Isolated Hypothyroxinemia in Women of Childbearing Age—Results from Retrospective Analysis by Karbownik-Lewińska, Małgorzata, Stępniak, Jan, Lewiński, Andrzej

“…Isolated hypothyroxinemia (IH) unfavorably affects reproduction. This study aimed to evaluate retrospectively if any routinely measured clinical/laboratory…”
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Melatonin reduces high levels of lipid peroxidation induced by potassium iodate in porcine thyroid by Iwan, Paulina, Stepniak, Jan, Karbownik-Lewinska, Malgorzata

“…Iodine is essential for thyroid hormone synthesis. Under normal iodine supply, calculated physiological iodine concentration in the thyroid is approx. 9 mM…”
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Sexual Dimorphism of NADPH Oxidase/H₂O₂ System in Rat Thyroid Cells; Effect of Exogenous 17β-Estradiol by Stepniak, Jan, Lewinski, Andrzej, Karbownik-Lewinska, Malgorzata

“…It has long been observed that females are more susceptible to thyroid diseases than males. Epidemiological and experimental data show that actions of hormonal…”
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Thyroid diseases in pregnancy: guidelines of the Polish Society of Endocrinology [Choroby tarczycy w ciąży: zalecenia postępowania Polskiego Towarzystwa Endokrynologicznego] by Hubalewska-Dydejczyk, Alicja, Trofimiuk-Müldner, Malgorzata, Ruchala, Marek, Lewiński, Andrzej, Bednarczuk, Tomasz, Zgliczyński, Wojciech, Syrenicz, Anhelli, Kos-Kudla, Beata, Jarząb, Barbara, Gietka-Czernel, Małgorzata, Szczepanek-Parulska, Ewelina, Krajewska, Jolanta, Andrysiak-Mamos, Elzbieta, Zygmunt, Arkadiusz, Karbownik-Lewińska, Malgorzata

“…Appropriate care of pregnant women with coexisting thyroid dysfunction is still a subject of much controversy. In recent years, there has been a dynamic…”
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Effects of melatonin treatment in septic newborns by GITTO, Eloisa, KARBOWNIK, Malgorzata, REITER, Russel J, DUN XIAN TAN, CUZZOCREA, Salvatore, CHIURAZZI, Pietro, CORDARO, Santa, CORONA, Giuseppina, TRIMARCHI, Giuseppe, BARBERI, Ignazio

“…Free radicals have been implicated in the pathogenesis of neonatal sepsis and its complications. This study was conducted to determine the changes in the…”
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Pro-Oxidative Effect of KIO3 and Protective Effect of Melatonin in the Thyroid—Comparison to Other Tissues by Iwan, Paulina, Stepniak, Jan, Karbownik-Lewinska, Malgorzata

“…Not only iodine deficiency, but also its excess may contribute to thyroid cancer. Potassium iodate (KIO3), which is broadly used in the salt iodization…”
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Cumulative Protective Effect of Melatonin and Indole-3-Propionic Acid against KIO3—Induced Lipid Peroxidation in Porcine Thyroid by Iwan, Paulina, Stepniak, Jan, Karbownik-Lewinska, Malgorzata

“…Iodine deficiency is the main environmental factor leading to thyroid cancer. At the same time iodine excess may also contribute to thyroid cancer. Potassium…”
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Correction: Iwan et al. Pro-Oxidative Effect of KIO3 and Protective Effect of Melatonin in the Thyroid—Comparison to Other Tissues. Life 2021, 11, 592 by Iwan, Paulina, Stepniak, Jan, Karbownik-Lewinska, Malgorzata

“…In the original article [...]…”
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Melatonin and Its Relation to the Immune System and Inflammation by REITER, RUSSEL J., CALVO, JUAN R., KARBOWNIK, MALGORZATA, QI, WENBO, TAN, DUN XIAN

“…: Melatonin (N‐acetyl‐5‐methoxytryptamine) was initially thought to be produced exclusively in the pineal gland. Subsequently its synthesis was demonstrated in…”
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Protective Effects of Melatonin against Carcinogen-Induced Oxidative Damage in the Thyroid by Stępniak, Jan, Karbownik-Lewińska, Małgorzata

“…Melatonin, primarily synthesized in the pineal gland, plays a crucial role in regulating circadian rhythms and possesses significant antioxidative properties…”
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Significance of melatonin in antioxidative defense system: reactions and products by Tan, D X, Manchester, L C, Reiter, R J, Qi, W B, Karbownik, M, Calvo, J R

“…Melatonin is a potent endogenous free radical scavenger, actions that are independent of its many receptor-mediated effects. In the last several years,…”
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Melatonin reverses the enhanced oxidative damage to membrane lipids and improves skin biophysical characteristics in former-smokers - A study in postmenopausal women by Sagan, Dorota, Stepniak, Jan, Gesing, Adam, Lewinski, Andrzej, Karbownik-Lewinska, Malgorzata

“…Protective antioxidative effects of melatonin have been repeatedly documented in experimental and clinical studies. One of the most spectacular exogenous…”
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High normal TSH is associated with lower mannan-binding lectin in women of childbearing age by Karbownik-Lewinska, Malgorzata, Stepniak, Jan, Marcinkowska, Magdalena, Krygier, Adrian, Lewinski, Andrzej

“…Mannan-binding lectin (MBL) is a main component of the lectin pathway of the complement system. Lower MBL levels are associated with, among other conditions,…”
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Fenton Reaction-Induced Oxidative Damage to Membrane Lipids and Protective Effects of 17β-Estradiol in Porcine Ovary and Thyroid Homogenates by Rynkowska, Aleksandra, Stępniak, Jan, Karbownik-Lewińska, Małgorzata

“…The Fenton reaction (Fe +H O →Fe + OH+OH ) results in strong oxidative damage to macromolecules when iron (Fe) or hydrogen peroxide (H O ) are in excess. This…”
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Correction to: High normal TSH is associated with lower mannan-binding lectin in women of childbearing age by Karbownik-Lewinska, Malgorzata, Stepniak, Jan, Marcinkowska, Magdalena, Krygier, Adrian, Lewinski, Andrzej

“…An amendment to this paper has been published and can be accessed via the original article…”
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Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo by Reiter, R J, Tan, D X, Qi, W, Manchester, L C, Karbownik, M, Calvo, J R

“…This brief resume summarizes the evidence which shows that melatonin is a significant free radical scavenger and antioxidant at both physiological and…”
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High level of oxidized nucleosides in thyroid mitochondrial DNA; damaging effects of Fenton reaction substrates by Karbownik-Lewińska, Małgorzata, Stępniak, Jan, Lewiński, Andrzej

“…The mitochondrial DNA (mtDNA) lies in close proximity to the free radical-producing electron transport chain, thus, it is highly prone to oxidative damage…”
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Molecular analysis of the RET and NTRK1 gene rearrangements in papillary thyroid carcinoma in the Polish population by Brzeziańska, Ewa, Karbownik, Małgorzata, Migdalska-Sek, Monika, Pastuszak-Lewandoska, Dorota, Włoch, Jan, Lewiński, Andrzej

“…Among different genetic factors involved in the pathogenesis of the papillary thyroid carcinoma (PTC), rearrangements of RET protooncogene (RET/PTC), as well…”
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