Search Results - "KAPTEIN, ROBERT"

The role of level anti-crossings in nuclear spin hyperpolarization by Ivanov, Konstantin L, Pravdivtsev, Andrey N, Yurkovskaya, Alexandra V, Vieth, Hans-Martin, Kaptein, Robert

“…Nuclear spin hyperpolarization is an important resource for increasing the sensitivity of NMR spectroscopy and MRI. Signal enhancements can be as large as 3-4…”
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Single-stranded DNA Binding by the Helix-Hairpin-Helix Domain of XPF Protein Contributes to the Substrate Specificity of the ERCC1-XPF Protein Complex by Das, Devashish, Faridounnia, Maryam, Kovacic, Lidija, Kaptein, Robert, Boelens, Rolf, Folkers, Gert E.

“…The nucleotide excision repair protein complex ERCC1-XPF is required for incision of DNA upstream of DNA damage. Functional studies have provided insights into…”
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Structure and Flexibility Adaptation in Nonspecific and Specific Protein-DNA Complexes by Kalodimos, Charalampos G., Biris, Nikolaos, Alexandre M. J. J. Bonvin, Levandoski, Marc M., Guennuegues, Marc, Boelens, Rolf, Kaptein, Robert

“…Interaction of regulatory DNA binding proteins with their target sites is usually preceded by binding to nonspecific DNA. This speeds up the search for the…”
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RECOORD: A recalculated coordinate database of 500+ proteins from the PDB using restraints from the BioMagResBank by Nederveen, Aart J., Doreleijers, Jurgen F., Vranken, Wim, Miller, Zachary, Spronk, Chris A.E.M., Nabuurs, Sander B., Güntert, Peter, Livny, Miron, Markley, John L., Nilges, Michael, Ulrich, Eldon L., Kaptein, Robert, Bonvin, Alexandre M.J.J.

“…State‐of‐the‐art methods based on CNS and CYANA were used to recalculate the nuclear magnetic resonance (NMR) solution structures of 500+ proteins for which…”
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The Cerebro-oculo-facio-skeletal Syndrome Point Mutation F231L in the ERCC1 DNA Repair Protein Causes Dissociation of the ERCC1-XPF Complex by Faridounnia, Maryam, Wienk, Hans, Kovačič, Lidija, Folkers, Gert E., Jaspers, Nicolaas G.J., Kaptein, Robert, Hoeijmakers, Jan H.J., Boelens, Rolf

“…The ERCC1-XPF heterodimer, a structure-specific DNA endonuclease, is best known for its function in the nucleotide excision repair (NER) pathway. The ERCC1…”
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Selective Hydrogenation of 1,3-Butadiene and 1-Butyne over a Rh/Chitosan Catalyst Investigated by using Parahydrogen-Induced Polarization by Barskiy, Danila A., Kovtunov, Kirill V., Primo, Ana, Corma, Avelino, Kaptein, Robert, Koptyug, Igor V.

“…Hydrogenation of 1,3‐butadiene and 1‐butyne over the Rh/chitosan catalyst in gaseous and liquid phases was investigated by using the NMR and…”
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On the Role of Aromatic Side Chains in the Photoactivation of BLUF Domains by Gauden, Magdalena, Grinstead, Jeffrey S, Laan, Wouter, van Stokkum, Ivo H. M, Avila-Perez, Marcela, Toh, K. C, Boelens, Rolf, Kaptein, Robert, van Grondelle, Rienk, Hellingwerf, Klaas J, Kennis, John T. M

“…BLUF (blue-light sensing using FAD) domain proteins are a novel group of blue-light sensing receptors found in many microorganisms. The role of the aromatic…”
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Light-Induced Flipping of a Conserved Glutamine Sidechain and Its Orientation in the AppA BLUF Domain by Grinstead, Jeffrey S, Avila-Perez, Marcela, Hellingwerf, Klaas J, Boelens, Rolf, Kaptein, Robert

“…The AppA BLUF domain is a blue light photoreceptor containing flavin. Conserved glutamine 63 is necessary for the photocycle of the protein, and its side chain…”
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AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR by Laskowski, R A, Rullmannn, J A, MacArthur, M W, Kaptein, R, Thornton, J M

“…The AQUA and PROCHECK-NMR programs provide a means of validating the geometry and restraint violations of an ensemble of protein structures solved by solution…”
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The Structure of the Human ERCC1/XPF Interaction Domains Reveals a Complementary Role for the Two Proteins in Nucleotide Excision Repair by Tripsianes, Konstantinos, Folkers, Gert, AB, Eiso, Das, Devashish, Odijk, Hanny, Jaspers, Nicolaas G.J., Hoeijmakers, Jan H.J., Kaptein, Robert, Boelens, Rolf

“…The human ERCC1/XPF complex is a structure-specific endonuclease with defined polarity that participates in multiple DNA repair pathways. We report the…”
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Toward an Integrated Model of Protein−DNA Recognition as Inferred from NMR Studies on the Lac Repressor System by KALODIMOS, Charalampos G., BOELENS, Rolf, KAPTEIN, Robert

“…Kalodimos et al summarize how NMR spectroscopy may address unique features of protein-DNA recognition. Kalodimos et al explain how the knowledge that has…”
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The Structure of the XPF-ssDNA Complex Underscores the Distinct Roles of the XPF and ERCC1 Helix- Hairpin-Helix Domains in ss/ds DNA Recognition by Das, Devashish, Folkers, Gert E., van Dijk, Marc, Jaspers, Nicolaas G.J., Hoeijmakers, Jan H.J., Kaptein, Robert, Boelens, Rolf

“…Human XPF/ERCC1 is a structure-specific DNA endonuclease that nicks the damaged DNA strand at the 5′ end during nucleotide excision repair. We determined the…”
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Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization by Tripsianes, Konstantinos, Folkers, Gert E, Zheng, Chao, Das, Devashish, Grinstead, Jeffrey S, Kaptein, Robert, Boelens, Rolf

“…Human ERCC1/XPF is a structure-specific endonuclease involved in multiple DNA repair pathways. We present the solution structure of the non-catalytic ERCC1…”
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Unique Conformer Selection of Human Growth-Regulatory Lectin Galectin-1 for Ganglioside GM1 versus Bacterial Toxins by Siebert, Hans-Christian, André, Sabine, Lu, Shan-Yun, Frank, Martin, Kaltner, Herbert, van Kuik, J. Albert, Korchagina, Elena Y, Bovin, Nicolai, Tajkhorshid, Emad, Kaptein, Robert, Vliegenthart, Johannes F. G, von der Lieth, Claus-Wilhelm, Jiménez-Barbero, Jesús, Kopitz, Jürgen, Gabius, Hans-Joachim

“…Endogenous lectins induce effects on cell growth by binding to antennae of natural glycoconjugates. These complex carbohydrates often present more than one…”
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The Solution Structure of a Transient Photoreceptor Intermediate: Δ25 Photoactive Yellow Protein by Bernard, Cédric, Houben, Klaartje, Derix, Nocky M., Marks, David, van der Horst, Michael A., Hellingwerf, Klaas J., Boelens, Rolf, Kaptein, Robert, van Nuland, Nico A.J.

“…The N-terminally truncated variant of photoactive yellow protein (Δ25-PYP) undergoes a very similar photocycle as the corresponding wild-type protein (WT-PYP),…”
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Recommendations for the presentation of NMR structures of proteins and nucleic acids (IUPAC Recommendations 1998) by Markley, John L., Bax, Ad, Arata, Yoji, Hilbers, C. W., Kaptein, Robert, Sykes, Brian D., Wright, Peter E., Wüthrich, Kurt

“…Abstract…”
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Recommendations for the presentation of NMR structures of proteins and nucleic acids. IUPAC-IUBMB-IUPAB Inter-Union Task Group on the Standardization of Data Bases of Protein and Nucleic Acid Structures Determined by NMR Spectroscopy by Markley, J L, Bax, A, Arata, Y, Hilbers, C W, Kaptein, R, Sykes, B D, Wright, P E, Wüthrich, K

“…The recommendations presented here are designed to support easier communication of NMR data and NMR structures of proteins and nucleic acids through unified…”
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Recommendations for the presentation of NMR structures of proteins and nucleic acids by Markley, J L, Bax, A, Arata, Y, Hilbers, C W, Kaptein, R, Sykes, B D, Wright, P E, Wüthrich, K

“…The recommendations presented here are designed to support easier communication of NMR data and NMR structures of proteins and nucleic acids through unified…”
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Solution Structure of the Human Ubiquitin-specific Protease 15 DUSP Domain by de Jong, Rob N., AB, Eiso, Diercks, Tammo, Truffault, Vincent, Daniëls, Mark, Kaptein, Robert, Folkers, Gert E.

“…Ubiquitin-specific proteases (USPs) can remove covalently attached ubiquitin moieties from target proteins and regulate both the stability and…”
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Gradual phosphorylation regulates PC4 coactivator function by Jonker, Hendrik R. A., Wechselberger, Rainer W., Pinkse, Martijn, Kaptein, Robert, Folkers, Gert E.

“…The unstructured N‐terminal domain of the transcriptional cofactor PC4 contains multiple phosphorylation sites that regulate activity. The phosphorylation…”
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