Search Results - "KAPSOGEORGOU, Efstathia K"
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Characteristics of the minor salivary gland infiltrates in Sjögren's syndrome
Published in Journal of autoimmunity (01-06-2010)“…Abstract Sjögren's syndrome (SS) is a chronic autoimmune exocrinopathy associated with variable degree of lymphocytic infiltration of the affected organs…”
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Type I and II interferon signatures in Sjogren's syndrome pathogenesis: Contributions in distinct clinical phenotypes and Sjogren's related lymphomagenesis
Published in Journal of autoimmunity (01-09-2015)“…Abstract Both type I and II interferons (IFNs) have been implicated in the pathogenesis of Sjogren's syndrome (SS). We aimed to explore the contribution of…”
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Autophagy and Metabolism in Normal and Malignant Hematopoiesis
Published in International journal of molecular sciences (09-08-2021)“…The hematopoietic system relies on regulation of both metabolism and autophagy to maintain its homeostasis, ensuring the self-renewal and multipotent…”
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The role of intrinsic epithelial activation in the pathogenesis of Sjögren’s syndrome
Published in Journal of autoimmunity (01-11-2010)“…Abstract Sjögren’s syndrome (SS) is a chronic autoimmune disorder that is characterized by dysfunction and destruction of the exocrine glands. Exocrinopathy is…”
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Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases
Published in Proceedings of the National Academy of Sciences - PNAS (23-10-2012)“…Elucidating the molecular pathways active in pathologic tissues has important implications for defining disease subsets, selecting therapy, and monitoring…”
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Serum, but Not Saliva, CXCL13 Levels Associate With Infiltrating CXCL13+ Cells in the Minor Salivary Gland Lesions and Other Histologic Parameters in Patients With Sjögren's Syndrome
Published in Frontiers in immunology (17-08-2021)“…Recent studies suggest that elevated CXCL13 serum levels in patients with primary Sjögren's syndrome (pSS) associate with minor salivary gland (MSG) histologic…”
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Akt Signaling Pathway Is Activated in the Minor Salivary Glands of Patients with Primary Sjögren's Syndrome
Published in International journal of molecular sciences (14-12-2021)“…Primary Sjögren's syndrome (pSS) is an autoimmune exocrinopathy of mainly the salivary and lacrimal glands associated with high prevalence of lymphoma. Akt is…”
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Occurrence and Antigenic Specificity of Perinuclear Anti-Neutrophil Cytoplasmic Antibodies (P-ANCA) in Systemic Autoimmune Diseases
Published in Cells (Basel, Switzerland) (19-08-2021)“…Perinuclear anti-neutrophilic cytoplasmic antibodies (P-ANCA) recognize heterogeneous antigens, including myeloperoxidase (MPO), lactoferrin, elastase,…”
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The role of epithelial cells in the pathogenesis of Sjögren's syndrome
Published in Clinical reviews in allergy & immunology (01-06-2007)“…Sjögren's syndrome (SS) is a chronic autoimmune exocrinopathy that is characterized by periductal mononuclear cell infiltrates in the affected exocrine glands…”
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Perturbation of transcriptome in non-neoplastic salivary gland epithelial cell lines derived from patients with primary Sjögren's syndrome
Published in Data in brief (01-04-2018)“…The data presented here are related to the research article titled “Impaired anti-inflammatory activity of PPARγ in the salivary epithelia of Sjögren's…”
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Predictive markers of lymphomagenesis in Sjögren's syndrome: From clinical data to molecular stratification
Published in Journal of autoimmunity (01-11-2019)“…Sjögren's syndrome (SS) is a chronic systemic autoimmune disease, affecting predominantly the exocrine glands, a large array of systemic manifestations and…”
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Insight into pathogenesis of Sjögren's syndrome: Dissection on autoimmune infiltrates and epithelial cells
Published in Clinical immunology (Orlando, Fla.) (01-09-2017)“…Abstract Sjögren's syndrome (SS) is a chronic autoimmune disease with broad clinical spectrum, extending from benign exocrinopathy to severe systemic disease…”
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Pathogenesis of Sjögren’s syndrome: What we know and what we should learn
Published in Journal of autoimmunity (01-08-2012)“…Abstract Sjögren’s syndrome (SS) or autoimmune epithelitis is a prototype autoimmune disorder with unique features: a broad clinical spectrum that extends from…”
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A comprehensive review of autoantibodies in primary Sjögren's syndrome: Clinical phenotypes and regulatory mechanisms
Published in Journal of autoimmunity (01-06-2014)“…Abstract Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by periepithelial lymphocytic infiltrates in affected tissues and the…”
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Low miR200b-5p levels in minor salivary glands: a novel molecular marker predicting lymphoma development in patients with Sjögren's syndrome
Published in Annals of the rheumatic diseases (01-08-2018)“…Development of non-Hodgkin's lymphoma (NHL) is the major adverse outcome of Sjögren's syndrome (SS) affecting both morbidity and mortality. Preliminary…”
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Expression of Long Interspersed Nuclear Element 1 Retroelements and Induction of Type I Interferon in Patients With Systemic Autoimmune Disease
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2016)“…Objective Increased expression of type I interferon (IFN) and a broad signature of type I IFN–induced gene transcripts are observed in patients with systemic…”
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Neutrophil extracellular traps in giant cell arteritis biopsies: presentation, localization and co-expression with inflammatory cytokines
Published in Rheumatology (Oxford, England) (11-04-2022)“…Abstract Objectives To explore the presence of neutrophil extracellular traps (NETs) in inflamed temporal artery biopsies (TABs) of patients with GCA. Methods…”
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Cell-specific epigenome-wide DNA methylation profile in long-term cultured minor salivary gland epithelial cells from patients with Sjögren's syndrome
Published in Annals of the rheumatic diseases (01-03-2017)“…The aetiology of primary Sjögren's syndrome (pSS), also referred to as autoimmune epithelitis, is incompletely understood but includes an epigenetic…”
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A biomarker for lymphoma development in Sjogren's syndrome: Salivary gland focus score
Published in Journal of autoimmunity (01-07-2021)“…The aim of this study is to explore the role of labial minor salivary gland (LMSG) focus score (FS) in stratifying Sjögren's Syndrome (SS) patients, lymphoma…”
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Impaired anti-inflammatory activity of PPARγ in the salivary epithelia of Sjögren's syndrome patients imposed by intrinsic NF-κB activation
Published in Journal of autoimmunity (01-01-2018)“…Sjögren's syndrome (SS) patients manifest inflammation in the salivary glands (SG) and evidence of persistent intrinsic activation of ductal SG epithelial…”
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