Search Results - "KAO, W. H. LINDA"

APOL1 Risk Variants, Race, and Progression of Chronic Kidney Disease by Parsa, Afshin, Kao, W.H. Linda, Xie, Dawei, Astor, Brad C, Li, Man, Hsu, Chi-yuan, Feldman, Harold I, Parekh, Rulan S, Kusek, John W, Greene, Tom H, Fink, Jeffrey C, Anderson, Amanda H, Choi, Michael J, Wright, Jackson T, Lash, James P, Freedman, Barry I, Ojo, Akinlolu, Winkler, Cheryl A, Raj, Dominic S, Kopp, Jeffrey B, He, Jiang, Jensvold, Nancy G, Tao, Kaixiang, Lipkowitz, Michael S, Appel, Lawrence J

“…In this study, APOL1 variants were associated with an increased risk of progression of chronic kidney disease in black patients, as compared with white…”
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Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study by Dehghan, Abbas, MD, Köttgen, Anna, MD, Yang, Qiong, PhD, Hwang, Shih-Jen, PhD, Kao, WH Linda, PhD, Rivadeneira, Fernando, MD, Boerwinkle, Eric, PhD, Levy, Daniel, MD, Hofman, Albert, MD, Astor, Brad C, PhD, Benjamin, Emelia J, MD, van Duijn, Cornelia M, PhD, Witteman, Jacqueline C, PhD, Coresh, Josef, MD, Fox, Caroline S, Dr

“…Summary Background Hyperuricaemia, a highly heritable trait, is a key risk factor for gout. We aimed to identify novel genes associated with serum uric acid…”
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Effect of zinc supplementation on insulin secretion: interaction between zinc and SLC30A8 genotype in Old Order Amish by Maruthur, Nisa M., Clark, Jeanne M., Fu, Mao, Linda Kao, W. H., Shuldiner, Alan R.

“…Aims/hypothesis SLC30A8 encodes a zinc transporter in the beta cell; individuals with a common missense variant (rs13266634; R325W) in SLC30A8 demonstrate a…”
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Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study by Bressler, Jan, Kao, W H Linda, Pankow, James S, Boerwinkle, Eric

“…Single nucleotide polymorphisms (SNPs) in the fat mass and obesity associated (FTO) gene are associated with body mass index (BMI) in populations of European…”
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A pseudolikelihood approach for assessing genetic association in case–control studies with unmeasured population structure by Chen, Yong, Liang, Kung-Yee, Tong, Pan, Beaty, Terri H, Barnes, Kathleen C, Linda Kao, WH

“…The case–control study design is one of the main tools for detecting associations between genetic markers and diseases. It is well known that population…”
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Nicotinic acetylcholine receptor genes on chromosome 15q25.1 are associated with nicotine and opioid dependence severity by Erlich, Porat M, Hoffman, Stuart N, Rukstalis, Margaret, Han, John J, Chu, Xin, Linda Kao, W. H, Gerhard, Glenn S, Stewart, Walter F, Boscarino, Joseph A

“…A locus on chromosome 15q25.1 previously implicated in nicotine, alcohol, and cocaine dependence, smoking, and lung cancer encodes subunits of the nicotinic…”
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Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans by Deo, Rahul C, Wilson, James G, Xing, Chao, Lawson, Kim, Kao, W H Linda, Reich, David, Tandon, Arti, Akylbekova, Ermeg, Patterson, Nick, Mosley, Jr, Thomas H, Boerwinkle, Eric, Taylor, Jr, Herman A

“…Lipoprotein(a) (Lp(a)) is an important causal cardiovascular risk factor, with serum Lp(a) levels predicting atherosclerotic heart disease and genetic…”
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Oral contraceptive pill use is associated with reduced odds of nonalcoholic fatty liver disease in menstruating women: results from NHANES III by Liu, Su-Hsun, Lazo, Mariana, Koteish, Ayman, Kao, W. H. Linda, Shih, Ming-Hsiung, Bonekamp, Susanne, Hernaez, Ruben, Clark, Jeanne M.

“…Background Higher prevalence of nonalcoholic fatty liver disease (NAFLD) in men and postmenopausal women than in premenopausal women has suggested a potential…”
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Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing by Köttgen, Anna, Yang, Qiong, Shimmin, Lawrence C, Tin, Adrienne, Schaeffer, Céline, Coresh, Josef, Liu, Xuan, Rampoldi, Luca, Hwang, Shih-Jen, Boerwinkle, Eric, Hixson, James E, Kao, W H Linda, Fox, Caroline S

“…Recent genome-wide association studies (GWAS) have identified common variants in the UMOD region associated with kidney function and disease in the general…”
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Association of Scavenger Receptor Class B Type I Polymorphisms With Subclinical Atherosclerosis: The Multi-Ethnic Study of Atherosclerosis by Naj, Adam C, West, Michael, Rich, Stephen S, Post, Wendy, Kao, W H. Linda, Wasserman, Bruce A, Herrington, David M, Rodriguez, Annabelle

“…BACKGROUND—Little is known about the association of scavenger receptor class B type I (SCARB1) single-nucleotide polymorphisms (SNPs) and subclinical…”
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Admixture mapping scans identify a locus affecting retinal vascular caliber in hypertensive African Americans: the Atherosclerosis Risk in Communities (ARIC) study by Cheng, Ching-Yu, Reich, David, Wong, Tien Y, Klein, Ronald, Klein, Barbara E K, Patterson, Nick, Tandon, Arti, Li, Man, Boerwinkle, Eric, Sharrett, A Richey, Kao, W H Linda

“…Retinal vascular caliber provides information about the structure and health of the microvascular system and is associated with cardiovascular and…”
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Biomarkers of vascular calcification and mortality in patients with ESRD by Scialla, Julia J, Kao, W H Linda, Crainiceanu, Ciprian, Sozio, Stephen M, Oberai, Pooja C, Shafi, Tariq, Coresh, Josef, Powe, Neil R, Plantinga, Laura C, Jaar, Bernard G, Parekh, Rulan S

“…Vascular calcification is common among patients undergoing dialysis and is associated with mortality. Factors such as osteoprotegerin (OPG), osteopontin (OPN),…”
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The Pharmacogenetics of Type 2 Diabetes: A Systematic Review by MARUTHUR, Nisa M, GRIBBLE, Matthew O, BENNETT, Wendy L, BOLEN, Shari, WILSON, Lisa M, BALAKRISHNAN, Poojitha, SAHU, Anita, BASS, Eric, KAO, W. H. LINDA, CLARK, Jeanne M

“…We performed a systematic review to identify which genetic variants predict response to diabetes medications. We performed a search of electronic databases…”
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Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene by Reich, David, Nalls, Michael A, Kao, W H Linda, Akylbekova, Ermeg L, Tandon, Arti, Patterson, Nick, Mullikin, James, Hsueh, Wen-Chi, Cheng, Ching-Yu, Coresh, Josef, Boerwinkle, Eric, Li, Man, Waliszewska, Alicja, Neubauer, Julie, Li, Rongling, Leak, Tennille S, Ekunwe, Lynette, Files, Joe C, Hardy, Cheryl L, Zmuda, Joseph M, Taylor, Herman A, Ziv, Elad, Harris, Tamara B, Wilson, James G

“…Persistently low white blood cell count (WBC) and neutrophil count is a well-described phenomenon in persons of African ancestry, whose etiology remains…”
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A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization by Chakravarti, Aravinda, Arking, Dan E, Pfeufer, Arne, Post, Wendy, Kao, W H Linda, Newton-Cheh, Christopher, Ikeda, Morna, West, Kristen, Kashuk, Carl, Akyol, Mahmut, Perz, Siegfried, Jalilzadeh, Shapour, Illig, Thomas, Gieger, Christian, Guo, Chao-Yu, Larson, Martin G, Wichmann, H Erich, Marbán, Eduardo, O'Donnell, Christopher J, Hirschhorn, Joel N, Kääb, Stefan, Spooner, Peter M, Meitinger, Thomas

“…Extremes of the electrocardiographic QT interval, a measure of cardiac repolarization, are associated with increased cardiovascular mortality. We identified a…”
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Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD by KÖTTGEN, Anna, HWANG, Shih-Jen, GUDNASON, Vilmundur, SHLIPAK, Michael G, QIONG YANG, CORESH, Josef, LEVY, Daniel, FOX, Caroline S, LARSON, Martin G, VAN EYK, Jennifer E, QIN FU, BENJAMIN, Emelia J, DEHGHAN, Abbas, GLAZER, Nicole L, LINDA KAO, W. H, HARRIS, Tamara B

“…Common variants in the region of the UMOD gene, which encodes uromodulin (Tamm-Horsfall protein), associate with chronic kidney disease (CKD) and estimated GFR…”
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Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk Factors by Yang, Qiong, Köttgen, Anna, Dehghan, Abbas, Smith, Albert V, Glazer, Nicole L, Chen, Ming-Huei, Chasman, Daniel I, Aspelund, Thor, Eiriksdottir, Gudny, Harris, Tamara B, Launer, Lenore, Nalls, Michael, Hernandez, Dena, Arking, Dan E, Boerwinkle, Eric, Grove, Megan L, Li, Man, Linda Kao, W.H, Chonchol, Michel, Haritunians, Talin, Li, Guo, Lumley, Thomas, Psaty, Bruce M, Shlipak, Michael, Hwang, Shih-Jen, Larson, Martin G, OʼDonnell, Christopher J, Upadhyay, Ashish, van Duijn, Cornelia M, Hofman, Albert, Rivadeneira, Fernando, Stricker, Bruno, Uitterlinden, Andre G, Paré, Guillaume, Parker, Alex N, Ridker, Paul M, Siscovick, David S, Gudnason, Vilmundur, Witteman, Jacqueline C, Fox, Caroline S, Coresh, Josef

“…BACKGROUND—Elevated serum urate levels can lead to gout and are associated with cardiovascular risk factors. We performed a genome-wide association study to…”
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The MYH9/APOL1 region and chronic kidney disease in European-Americans by O'Seaghdha, Conall M, Parekh, Rulan S, Hwang, Shih-Jen, Li, Man, Köttgen, Anna, Coresh, Josef, Yang, Qiong, Fox, Caroline S, Kao, W H Linda

“…Polymorphisms in the MYH9 and adjacent APOL1 gene region demonstrate a strong association with non-diabetic kidney disease in African-Americans. However, it is…”
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Association of Functional Polymorphism rs2231142 (Q141K) in the ABCG2 Gene With Serum Uric Acid and Gout in 4 US Populations The PAGE Study by LILI ZHANG, SPENCER, Kylee L, FRANCESCHINI, Nora, GAFFO, Angelo L, GLENN, Kimberly R, HEISS, Gerardo, JENNY, Nancy S, KOTTGEN, Anna, QIONG LI, KIANG LIU, MATISE, Tara C, NORTH, Kari E, VORUGANTI, V. Saroja, UMANS, Jason G, LINDA KAO, W. H, JORGENSEN, Neal W, FORNAGE, Myriam, BEST, Lyle G, BROWN-GENTRY, Kristin D, COLE, Shelley A, CRAWFORD, Dana C, DEELMAN, Ewa

“…A loss-of-function mutation (Q141K, rs2231142) in the ATP-binding cassette, subfamily G, member 2 gene (ABCG2) has been shown to be associated with serum uric…”
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Common Genetic Variants Associate with Serum Phosphorus Concentration by KESTENBAUM, Bryan, GLAZER, Nicole L, GIEGER, Christian, RIED, Janina S, MEITINGER, Thomas, STROM, Tim M, WICHMANN, H. Erich, CAMPBELL, Harry, HAYWARD, Caroline, RUDAN, Igor, DE BOER, Ian H, PSATY, Bruce M, KÖTTGEN, Anna, RICE, Kenneth M, IDA CHEN, Yii-Der, MAN LI, ARKING, Dan E, BOERWINKLE, Eric, CORESH, Josef, QIONG YANG, LEVY, Daniel, VAN ROOIJ, Frank J. A, DEHGHAN, Abbas, FELIX, Janine F, RIVADENEIRA, Fernando, UITTERLINDEN, André G, HOFMAN, Albert, VAN DUIJN, Cornelia M, SHLIPAK, Michael G, LINDA KAO, W. H, WITTEMAN, Jacqueline C. M, SISCOVICK, David S, FOX, Caroline S, HWANG, Shih-Jen, YONGMEI LIU, LOHMAN, Kurt, KRITCHEVSKY, Stephen B, HAUSMAN, Dorothy B, PETERSEN, Ann-Kristin

“…Phosphorus is an essential mineral that maintains cellular energy and mineralizes the skeleton. Because complex actions of ion transporters and regulatory…”
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