Search Results - "KANZAWA, T"

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells by Kanzawa, T, Germano, I M, Komata, T, Ito, H, Kondo, Y, Kondo, S

“…Autophagy is originally named as a process of protein recycling. It begins with sequestering cytoplasmic organelles in a membrane vacuole called autophagosome…”
Get full text

Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells by TAKEUCHI, H, KANZAWA, T, KONDO, Y, KONDO, S

“…Malignant gliomas highly coexpress platelet-derived growth factor (PDGF) and its receptor, suggesting the presence of an autocrine loop. Therefore, disruption…”
Get full text

Ionizing radiation induces apoptosis and inhibits neuronal differentiation in rat neural stem cells via the c-Jun NH2-terminal kinase (JNK) pathway by KANZAWA, T, IWADO, E, AOKI, H, IWAMARU, A, HOLLINGSWORTH, E. F, SAWAYA, R, KONDO, S, KONDO, Y

“…A substantial number of neural stem cells (NSCs) continue to proliferate and generate neurons in the central nervous system throughout life. Ionizing…”
Get full text

Antitumour effect of cyclin-dependent kinase inhibitors (p16 , p18 , p19 , p21 and p27 ) on malignant glioma cells by KOMATA, T, KANZAWA, T, TAKEUCHI, H, GERMANO, I. M, SCHREIBER, M, KONDO, Y, KONDO, S

“…Cyclin-dependent kinase inhibitors (CDKIs) are considered as novel anticancer agents because of their ability to induce growth arrest or apoptosis in tumour…”
Get full text

Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide by Kanzawa, T, Germano, I M, Kondo, Y, Ito, H, Kyo, S, Kondo, S

“…Temozolomide (TMZ, 3,4-dihydro-3-methyl-4-oxoimidazo [5,1-d]-as-tetrazine-8-carboxamide) is a new alkylating agent with promising antitumour efficacy for…”
Get full text

Evaluation of hafnium nitride thin films sputtered from a hafnium nitride target by Kanzawa, T., Setojima, N., Miyata, Y., Gotoh, Y., Tsuji, H., Ishikawa, J.

“…Hafnium nitride (HfN) thin films were prepared on Si (100) substrates by radio frequency magnetron sputtering with a compound target. Nitrogen composition,…”
Get full text

Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells by Komata, T, Kanzawa, T, Nashimoto, T, Aoki, H, Endo, S, Kon, T, Takahashi, H, Kondo, S, Tanaka, R

“…Histone deacetylase (HDAC) inhibitors have both apoptotic and differentiating effects on various tumor cells. However, the mechanisms underlying the effect of…”
Get more information

The role of autophagy in cancer development and response to therapy by Kondo, Seiji, Kondo, Yasuko, Kanzawa, Takao, Sawaya, Raymond

“…Autophagy is a process in which subcellular membranes undergo dynamic morphological changes that lead to the degradation of cellular proteins and cytoplasmic…”
Get full text

Performance of Subaru Cassegrain Adaptive Optics System by Takami, Hideki, Takato, Naruhisa, Hayano, Yutaka, Iye, Masanori, Oya, Shin, Kamata, Yukiko, Kanzawa, Tomio, Minowa, Yosuke, Otsubo, Masashi, Nakashima, Koji, Gaessler, Wolfgang, Saint-Jacques, David

“…The design and performance of the Cassegrain Adaptive Optics (AO) system for the 8.2 m Subaru Telescope are reported. The system is based on a curvature…”
Get full text

Induction of autophagic cell death in malignant glioma cells by arsenic trioxide by KANZAWA, Takao, KONDO, Yasuko, ITO, Hideaki, KONDO, Seiji, GERMANO, Isabelle

“…Recent clinical data shows that arsenic trioxide (As(2)O(3)) causes remission in patients with acute promyelocytic leukemia and multiple myeloma without severe…”
Get full text

Living ring-opening polymerization of ε-caprolactone with combinations of tert-butyllithium and bilky aluminium phenoxides by KITAYAMA, Tatsuki, YAMAGUCHI, Hiroko, KANZAWA, Takeshi, HIRANO, Tomohiro

Get full text

Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells by Ito, Hideaki, Daido, Shigeru, Kanzawa, Takao, Kondo, Seiji, Kondo, Yasuko

“…Autophagy is a novel response of cancer cells to ionizing radiation (IR) or chemotherapy, but its significance or mechanism remains largely elusive. Autophagy…”
Get more information

Melanotic cerebral astrocytoma : case report and literature review by KANZAWA, T, TAKAHASHI, H, HAYANO, M, MORI, S, SHIMBO, Y, KITAZAWA, T

“…We describe the case of 47-year-old man with a cystic, melanotic temporal lobe astrocytoma who had a history of complex partial seizures. The tumor mass was…”
Get full text

Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors by TAKEUCHI, Hayato, KONDO, Yasuko, FUJIWARA, Keishi, KANZAWA, Takao, AOKI, Hiroshi, MILLS, Gordon B, KONDO, Seiji

“…The mammalian target of rapamycin (mTOR) is a downstream effector of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway and a…”
Get full text

Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells by DAIDO, Shigeru, KANZAWA, Takao, YAMAMOTO, Akitsugu, TAKEUCHI, Hayato, KONDO, Yasuko, KONDO, Seiji

“…The sphingolipid ceramide has been recognized as an important second messenger implicated in regulating diverse signaling pathways especially for apoptosis…”
Get full text

Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3 by KANZAWA, Takao, LI ZHANG, LIANCHUN XIAO, GERMANO, Isabelle M, KONDO, Yasuko, KONDO, Seiji

“…Arsenic trioxide (As(2)O(3)) has shown considerable efficacy in treating hematological malignancies with induction of programmed cell death (PCD) type I,…”
Get full text

Molecular response of human glioblastoma multiforme cells to ionizing radiation : cell cycle arrest, modulation of the expression of cyclin-dependent kinase inhibitors, and autophagy by YAO, Kevin C, KOMATA, Tadashi, KONDO, Yasuko, KANZAWA, Takao, KONDO, Seiji, GERMANO, Isabelle M

“…Ionizing radiation is the gold-standard adjuvant treatment for glioblastoma multiforme (GBM), the most aggressive primary brain tumor. The mechanisms…”
Get full text

Inhibition of DNA repair for sensitizing resistant glioma cells to temozolomide by KANZAWA, Takao, BEDWELL, Joshua, KONDO, Yasuko, KONDO, Seui, GERMANO, Isabelle M

“…Temozolomide (TMZ) is a DNA alkylating agent currently used as adjuvant treatment for anaplastic astrocytomas. Its use in managing glioblastoma multiforme has…”
Get full text

Telomerase as a therapeutic target for malignant gliomas by Komata, T, Kanzawa, T, Kondo, Y, Kondo, S

“…Telomerase, a ribonucleoprotein enzyme, is considered as a potential target of cancer therapy because of its preferential expression in tumors. In particular,…”
Get full text

Inverse optimal tracking control of an aerial blimp robot by Fukao, T., Kanzawa, T., Osuka, K.

“…Inverse optimal tracking control is applied to an aerial blimp which is one of the underactuated systems. In the inverse optimal control approach, a controller…”
Get full text