Search Results - "KANT, JEFFREY A."

Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas by Beckner, Marie E., Fellows‐Mayle, Wendy, Zhang, Zhe, Agostino, Naomi R., Kant, Jeffrey A., Day, Billy W., Pollack, Ian F.

“…Glioblastomas, the most malignant type of glioma, are more glycolytic than normal brain tissue. Robust migration of glioblastoma cells has been previously…”
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The Histopathology of PRSS1 Hereditary Pancreatitis by Singhi, Aatur D., Pai, Reetesh K., Kant, Jeffrey A., Bartholow, Tanner L., Zeh, Herbert J., Lee, Kenneth K., Wijkstrom, Martin, Yadav, Dhiraj, Bottino, Rita, Brand, Randall E., Chennat, Jennifer S., Lowe, Mark E., Papachristou, Georgios I., Slivka, Adam, Whitcomb, David C., Humar, Abhinav

“…Hereditary pancreatitis is an autosomal dominant disorder with 80% penetrance and variable expressivity. The vast majority of cases have been linked to…”
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Limitations of the criteria used to diagnose histologic endometritis in epidemiologic pelvic inflammatory disease research by Miguel, Rodolfo D.Vicetti, Chivukula, Mamatha, Krishnamurti, Uma, Amortegui, Antonio J., Kant, Jeffrey A., Sweet, Richard L., Wiesenfeld, Harold C., Phillips, Jaclyn M., Cherpes, Thomas L.

“…While endometrial neutrophils and plasma cells are criteria used to diagnose histologic endometritis in epidemiologic pelvic inflammatory disease (PID)…”
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Clinical laboratory reports in molecular pathology by Gulley, Margaret L, Braziel, Rita M, Halling, Kevin C, Hsi, Eric D, Kant, Jeffrey A, Nikiforova, Marina N, Nowak, Jan A, Ogino, Shuji, Oliveira, Andre, Polesky, Herbert F, Silverman, Lawrence, Tubbs, Raymond R, Van Deerlin, Vivianna M, Vance, Gail H, Versalovic, James

“…Molecular pathology is a rapidly growing area of laboratory medicine in which DNA and RNA are analyzed. The recent introduction of array technology has added…”
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Cutaneous Marginal Zone Lymphomas Have Distinctive Features and Include 2 Subsets by EDINGER, James T, KANT, Jeffrey A, SWERDLOW, Steven H

“…Cutaneous marginal zone lymphomas (CMZL) were segregated in the WHO/EORTC consensus classification but grouped with other MALT lymphomas in the subsequent WHO…”
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Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors by Shuda, Masahiro, Arora, Reety, Kwun, Hyun Jin, Feng, Huichen, Sarid, Ronit, Fernández‐Figueras, María‐Teresa, Tolstov, Yanis, Gjoerup, Ole, Mansukhani, Mahesh M., Swerdlow, Steven H., Chaudhary, Preet M., Kirkwood, John M., Nalesnik, Michael A., Kant, Jeffrey A., Weiss, Lawrence M., Moore, Patrick S., Chang, Yuan

“…Merkel cell polyomavirus (MCV) is a recently discovered human virus closely related to African green monkey lymphotropic polyomavirus. MCV DNA is integrated in…”
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High Frequency of SDHB Germline Mutations in Patients with Malignant Catecholamine-Producing Paragangliomas: Implications for Genetic Testing by Brouwers, Frederieke M., Eisenhofer, Graeme, Tao, Jessica J., Kant, Jeffrey A., Adams, Karen T., Linehan, W. Marston, Pacak, Karel

“…Context: Adrenal and extraadrenal paragangliomas are tumors of chromaffin cells that are usually benign but that may also develop into malignant disease…”
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Recalcitrance of bacterial vaginosis among herpes-simplex-virus-type-2-seropositive women by Stoner, Kevin A., Reighard, Seth D., Miguel, Rodolfo D. Vicetti, Landsittel, Douglas, Cosentino, Lisa A., Kant, Jeffrey A., Cherpes, Thomas L.

“…Aim:  The multifactorial etiology of bacterial vaginosis (BV) impedes development of effective treatment and prevention strategies. Herein, we evaluated the…”
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Genetic Counseling for Nonsyndromic Pancreatitis by Fink, Erin N., MS, Kant, Jeffrey A., MD, PhD, FCAP, FAAAS, Whitcomb, David C., MD, PhD

“…An appreciation for the background of disease, not to mention the medical management of individuals, may be significantly affected by testing for mutations and…”
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The Journal of Molecular Diagnostics: From Conception to Contract by Kant, Jeffrey A., M.D., Ph.D. AMP, McManus, Linda M., Ph.D. President, ASIP

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Opportunities and challenges associated with clinical diagnostic genome sequencing: a report of the Association for Molecular Pathology by Schrijver, Iris, Aziz, Nazneen, Farkas, Daniel H, Furtado, Manohar, Gonzalez, Andrea Ferreira, Greiner, Timothy C, Grody, Wayne W, Hambuch, Tina, Kalman, Lisa, Kant, Jeffrey A, Klein, Roger D, Leonard, Debra G B, Lubin, Ira M, Mao, Rong, Nagan, Narasimhan, Pratt, Victoria M, Sobel, Mark E, Voelkerding, Karl V, Gibson, Jane S

“…This report of the Whole Genome Analysis group of the Association for Molecular Pathology illuminates the opportunities and challenges associated with clinical…”
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Array-Based Karyotyping for Prognostic Assessment in Chronic Lymphocytic Leukemia by Hagenkord, Jill M, Monzon, Federico A, Kash, Shera F, Lilleberg, Stan, Xie, Qingmei, Kant, Jeffrey A

“…Specific chromosomal alterations are recognized as important prognostic factors in chronic lymphocytic leukemia (CLL). Array-based karyotyping is gaining…”
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Design and analytical validation of clinical DNA sequencing assays by Pont-Kingdon, Genevieve, Gedge, Friederike, Wooderchak-Donahue, Whitney, Schrijver, Iris, Weck, Karen E, Kant, Jeffrey A, Oglesbee, Devin, Bayrak-Toydemir, Pinar, Lyon, Elaine

“…DNA sequencing is the method of choice for mutation detection in many genes. To demonstrate the analytical accuracy and reliability of DNA sequencing assays…”
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Array-Based Karyotyping for Prognostic Assessment in Chronic Lymphocytic Leukemia: Performance Comparison of Affymetrix 10K2.0, 250K Nsp, and SNP6.0 Arrays by Hagenkord, Jill M, Monzon, Federico A, Kash, Shera F, Lilleberg, Stan, Xie, Qingmei, Kant, Jeffrey A

“…Specific chromosomal alterations are recognized as important prognostic factors in chronic lymphocytic leukemia (CLL). Array-based karyotyping is gaining…”
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Epigenetic abnormality of SRY gene in the adult XY female with pericentric inversion of the Y chromosome by Mitsuhashi, Tomoko, Warita, Katsuhiko, Sugawara, Teruo, Tabuchi, Yoshiaki, Takasaki, Ichiro, Kondo, Takashi, Hayashi, Fumio, Wang, Zhi-Yu, Matsumoto, Yoshiki, Miki, Takanori, Takeuchi, Yoshiki, Ebina, Yasuhiko, Yamada, Hideto, Sakuragi, Noriaki, Yokoyama, Toshifumi, Nanmori, Takashi, Kitagawa, Hiroshi, Kant, Jeffrey A., Hoshi, Nobuhiko

“…ABSTRACT In normal ontogenetic development, the expression of the sex‐determining region of the Y chromosome (SRY) gene, involved in the first step of male sex…”
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CD123 immunohistochemical expression in acute myeloid leukemia is associated with underlying FLT3-ITD and NPM1 mutations by Rollins-Raval, Marian, Pillai, Raju, Warita, Katsuhiko, Mitsuhashi-Warita, Tomoko, Mehta, Rohtesh, Boyiadzis, Michael, Djokic, Miroslav, Kant, Jeffrey A, Roth, Christine G

“…FLT3-ITD and NPM1 mutation testing in acute myeloid leukemia (AML) plays an important role in prognostic risk stratification, especially within the…”
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The business of genomic testing: a survey of early adopters by Crawford, James M., Bry, Lynn, Pfeifer, John, Caughron, Samuel K., Black-Schaffer, Stephen, Kant, Jeffrey A., Kaufman, Jill H.

“…Purpose: The practice of “genomic” (or “personalized”) medicine requires the availability of appropriate diagnostic testing. Our study objective was to…”
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Next generation sequencing in clinical medicine: Challenges and lessons for pathology and biomedical informatics by Gullapalli, Rama R., Desai, Ketaki V., Santana-Santos, Lucas, Kant, Jeffrey A., Becich, Michael J.

“…The Human Genome Project (HGP) provided the initial draft of mankind's DNA sequence in 2001. The HGP was produced by 23 collaborating laboratories using Sanger…”
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The Associations Between Pelvic Inflammatory Disease, Trichomonas vaginalis Infection, and Positive Herpes Simplex Virus Type 2 Serology by CHERPES, THOMAS L, WIESENFELD, HAROLD C., MELAN, MELISSA A., KANT, JEFFREY A., COSENTINO, LISA A., MEYN, LESLIE A., HILLIER, SHARON L.

“…Objective: Roles for Chlamydia trachomatis and Neisseria gonorrhoeae infections in pelvic inflammatory disease pathogenesis are well delineated; however, the…”
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Global gene profiling and comprehensive bioinformatics analysis of a 46,XY female with pericentric inversion of the Y chromosome by Mitsuhashi, Tomoko, Warita, Katsuhiko, Tabuchi, Yoshiaki, Takasaki, Ichiro, Kondo, Takashi, Sugawara, Teruo, Hayashi, Fumio, Wang, Zhi-Yu, Matsumoto, Yoshiki, Miki, Takanori, Takeuchi, Yoshiki, Ebina, Yasuhiko, Yamada, Hideto, Sakuragi, Noriaki, Yokoyama, Toshifumi, Nanmori, Takashi, Kitagawa, Hiroshi, Kant, Jeffrey A., Hoshi, Nobuhiko

“…ABSTRACT XY females are rare individuals who carry a Y chromosome but are phenotypically female. In approximately 80–90% of these cases, there are no mutations…”
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