Search Results - "KANNAGI, Mari"

Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL by Kannagi, Mari, Hasegawa, Atsuhiko, Nagano, Yoshiko, Kimpara, Shuichi, Suehiro, Youko

“…Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP),…”
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Maintenance of long remission in adult T‐cell leukemia by Tax‐targeted vaccine: A hope for disease‐preventive therapy by Kannagi, Mari, Hasegawa, Atsuhiko, Nagano, Yoshiko, Iino, Tadafumi, Okamura, Jun, Suehiro, Youko

“…Adult T‐cell leukemia/lymphoma (ATL) is an aggressive lymphoproliferative disease caused by human T‐cell leukemia virus type 1 (HTLV‐1). Multi‐agent…”
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IL-10-mediated signals act as a switch for lymphoproliferation in Human T-cell leukemia virus type-1 infection by activating the STAT3 and IRF4 pathways by Sawada, Leila, Nagano, Yoshiko, Hasegawa, Atsuhiko, Kanai, Hikari, Nogami, Kai, Ito, Sayaka, Sato, Tomoo, Yamano, Yoshihisa, Tanaka, Yuetsu, Masuda, Takao, Kannagi, Mari

“…Human T-cell leukemia virus type-1 (HTLV-1) causes two distinct diseases, adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical…”
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Vaccination with short-term-cultured autologous PBMCs efficiently activated STLV-1-specific CTLs in naturally STLV-1-infected Japanese monkeys with impaired CTL responses by Hasegawa, Atsuhiko, Murata, Megumi, Fujikawa, Tomoka, Katagiri, Kuniko, Nagano, Yoshiko, Masuda, Takao, Kuramitsu, Madoka, Nakajima, Shinsuke, Fujisawa, Jun-Ichi, Okuma, Kazu, Grover, Poonam, Kidiga, Maureen, Akari, Hirofumi, Kannagi, Mari

“…A small proportion of human T-cell leukemia virus type-1 (HTLV-1)-infected individuals develop adult T-cell leukemia/lymphoma, a chemotherapy-resistant…”
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Fate of HIV-1 cDNA intermediates during reverse transcription is dictated by transcription initiation site of virus genomic RNA by Masuda, Takao, Sato, Yoko, Huang, Yu-Lun, Koi, Satoshi, Takahata, Tatsuro, Hasegawa, Atsuhiko, Kawai, Gota, Kannagi, Mari

“…Retroviral reverse transcription is accomplished by sequential strand-transfers of partial cDNA intermediates copied from viral genomic RNA. Here, we revealed…”
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Short‐term cultured autologous peripheral blood mononuclear cells as a potential immunogen to activate Tax‐specific CTL response in adult T‐cell leukemia patients by Ishizawa, Miku, Ganbaatar, Undrakh, Hasegawa, Atsuhiko, Takatsuka, Natsuko, Kondo, Nobuyo, Yoneda, Takeru, Katagiri, Kuniko, Masuda, Takao, Utsunomiya, Atae, Kannagi, Mari

“…Activation of CD8+ Tax‐specific CTL is a new therapeutic concept for adult T‐cell leukemia (ATL) caused by HTLV‐1. A recent clinical study of the dendritic…”
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HTLV-1 Tax-Specific CTL Epitope-Pulsed Dendritic Cell Therapy Reduces Proviral Load in Infected Rats with Immune Tolerance against Tax by Ando, Satomi, Hasegawa, Atsuhiko, Murakami, Yuji, Zeng, Na, Takatsuka, Natsuko, Maeda, Yasuhiro, Masuda, Takao, Suehiro, Youko, Kannagi, Mari

“…Adult T cell leukemia/lymphoma (ATL), a CD4 T cell malignancy with a poor prognosis, is caused by human T cell leukemia virus type 1 (HTLV-1) infection. High…”
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Effective Suppression of Human Immunodeficiency Virus Type 1 through a Combination of Short- or Long-Hairpin RNAs Targeting Essential Sequences for Retroviral Integration by NISHITSUJI, Hironori, KOHARA, Michinori, KANNAGI, Mari, MASUDA, Takao

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Immunologic control of human T-cell leukemia virus type I and adult T-cell leukemia by KANNAGI, Mari

“…Host T-cell responses to human T-cell leukemia virus type I (HTLV-I) control the expansion of HTLV-I-infected cells and are determinants of the equilibrium…”
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Stromal Cell-Mediated Suppression of Human T-Cell Leukemia Virus Type 1 Expression In Vitro and In Vivo by Type I Interferon by KINPARA, Shuichi, HASEGAWA, Atsuhiko, UTSUNOMIYA, Atae, NISHITSUJI, Hironori, FURUKAWA, Hiroyuki, MASUDA, Takao, KANNAGI, Mari

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Identification of a Novel Human Immunodeficiency Virus Type 1 Integrase Interactor, Gemin2, That Facilitates Efficient Viral cDNA Synthesis In Vivo by HAMAMOTO, Seiji, NISHITSUJI, Hironori, AMAGASA, Teruo, KANNAGI, Mari, MASUDA, Takao

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Double control systems for human T‐cell leukemia virus type 1 by innate and acquired immunity by Kannagi, Mari, Hasegawa, Atsuhiko, Kinpara, Shuichi, Shimizu, Yukiko, Takamori, Ayako, Utsunomiya, Atae

“…Human T‐cell leukemia virus type 1 (HTLV‐1) is the causative retrovirus of adult T‐cell leukemia (ATL) and HTLV‐1‐associated myelopathy/tropical spastic…”
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Augmentation of reverse transcription by integrase through an interaction with host factor, SIP1/Gemin2 Is critical for HIV-1 infection by Nishitsuji, Hironori, Hayashi, Takaya, Takahashi, Takuya, Miyano, Masashi, Kannagi, Mari, Masuda, Takao

“…There has been accumulating evidence for the involvement of retroviral integrase (IN) in the reverse transcription of viral RNA. We previously identified a…”
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Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis by Lee, Junghee, Kannagi, Mari, Ferrante, Robert J, Kowall, Neil W, Ryu, Hoon

“…Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by selective degeneration of motor neurons and glial activation…”
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Functional impairment of Tax-specific but not cytomegalovirus-specific CD8+ T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers by Takamori, Ayako, Hasegawa, Atsuhiko, Utsunomiya, Atae, Maeda, Yasuhiro, Yamano, Yoshihisa, Masuda, Masato, Shimizu, Yukiko, Tamai, Yotaro, Sasada, Amane, Zeng, Na, Choi, Ilseung, Uike, Naokuni, Okamura, Jun, Watanabe, Toshiki, Masuda, Takao, Kannagi, Mari

“…Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a…”
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Prediction of prognosis of ALS: Importance of active denervation findings of the cervical-upper limb area and trunk area by Sato, Yoko, Nakatani, Eiji, Watanabe, Yasuhiro, Fukushima, Masanori, Nakashima, Kenji, Kannagi, Mari, Kanatani, Yasuhiro, Mizushima, Hiroshi

“…Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by serious muscle atrophy and weakness. The purpose of this study was to find…”
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Evaluation of the Functional Involvement of Human Immunodeficiency Virus Type 1 Integrase in Nuclear Import of Viral cDNA during Acute Infection by IKEDA, Tamako, NISHITSUJI, Hironori, XIN ZHOU, NARA, Nobuo, OHASHI, Takashi, KANNAGI, Mari, MASUDA, Takao

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Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells by Nishitsuji, Hironori, Ikeda, Tamako, Miyoshi, Hiroyuki, Ohashi, Takashi, Kannagi, Mari, Masuda, Takao

“…RNA interference (RNAi) is a sequence-specific RNA degradation process mediated by short double-stranded RNAs termed small interfering RNAs. Here, we describe…”
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Role of Phosphatidylinositol 3-Kinase in Friend Spleen Focus-Forming Virus-Induced Erythroid Disease by Umehara, Daigo, Watanabe, Shinya, Ochi, Haruyo, Anai, Yukari, Ahmed, Nursarat, Kannagi, Mari, Hanson, Charlotte, Ruscetti, Sandra, Nishigaki, Kazuo

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Impaired Tax‐specific T‐cell responses with insufficient control of HTLV‐1 in a subgroup of individuals at asymptomatic and smoldering stages by Shimizu, Yukiko, Takamori, Ayako, Utsunomiya, Atae, Kurimura, Mayumi, Yamano, Yoshihisa, Hishizawa, Masakatsu, Hasegawa, Atsuhiko, Kondo, Fumiaki, Kurihara, Kiyoshi, Harashima, Nanae, Watanabe, Toshiki, Okamura, Jun, Masuda, Takao, Kannagi, Mari

“…Human T‐cell leukemia virus type‐1 (HTLV‐1)‐specific T‐cell immunity, a potential antitumor surveillance system in vivo, is impaired in adult T‐cell leukemia…”
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