Search Results - "KANG, Peter M"
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Recent Advances in Nanocarrier-Assisted Therapeutics Delivery Systems
Published in Pharmaceutics (01-09-2020)“…Nanotechnologies have attracted increasing attention in their application in medicine, especially in the development of new drug delivery systems. With the…”
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Systemic Review of Biodegradable Nanomaterials in Nanomedicine
Published in Nanomaterials (Basel, Switzerland) (01-04-2020)“…Nanomedicine is a field of science that uses nanoscale materials for the diagnosis and treatment of human disease. It has emerged as an important aspect of the…”
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Oxidative Stress and Antioxidant Treatments in Cardiovascular Diseases
Published in Antioxidants (17-12-2020)“…Oxidative stress plays a key role in many physiological and pathological conditions. The intracellular oxidative homeostasis is tightly regulated by the…”
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Highly conductive, stretchable and biocompatible Ag–Au core–sheath nanowire composite for wearable and implantable bioelectronics
Published in Nature nanotechnology (01-11-2018)“…Wearable and implantable devices require conductive, stretchable and biocompatible materials. However, obtaining composites that simultaneously fulfil these…”
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Guidelines for evaluating myocardial cell death
Published in American journal of physiology. Heart and circulatory physiology (01-11-2019)“…Cell death is a fundamental process in cardiac pathologies. Recent studies have revealed multiple forms of cell death, and several of them have been…”
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Therapeutic use of H2O2-responsive anti-oxidant polymer nanoparticles for doxorubicin-induced cardiomyopathy
Published in Biomaterials (01-07-2014)“…Doxorubicin (DOX) is a commonly used anti-neoplastic agent but its clinical use is limited due to serious hepatic and cardiac side effects. DOX-induced…”
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MicroRNA-1 Negatively Regulates Expression of the Hypertrophy-Associated Calmodulin and Mef2a Genes
Published in Molecular and Cellular Biology (01-04-2009)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Systematic Review on Advances in Management of Oxidative Stress-Associated Cardiovascular Diseases
Published in Antioxidants (29-07-2024)“…Oxidative stress plays a significant role in the pathogenesis of cardiovascular diseases, such as myocardial ischemia/reperfusion injury, atherosclerosis,…”
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H2O2-responsive molecularly engineered polymer nanoparticles as ischemia/reperfusion-targeted nanotherapeutic agents
Published in Scientific reports (19-07-2013)“…The main culprit in the pathogenesis of ischemia/reperfusion (I/R) injury is the overproduction of reactive oxygen species (ROS). Hydrogen peroxide (H 2 O 2 ),…”
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A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity
Published in Nature communications (08-01-2016)“…Previous studies have shown that biological noise may drive dynamic phenotypic mosaicism in isogenic unicellular organisms. However, there is no evidence for a…”
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Hydrogen peroxide-activatable antioxidant prodrug as a targeted therapeutic agent for ischemia-reperfusion injury
Published in Scientific reports (13-11-2015)“…Overproduction of hydrogen peroxide (H 2 O 2 ) causes oxidative stress and is the main culprit in the pathogenesis of ischemia/reperfusion (I/R) injury…”
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Activated Vitamin D Attenuates Left Ventricular Abnormalities Induced by Dietary Sodium in Dahl Salt-Sensitive Animals
Published in Proceedings of the National Academy of Sciences - PNAS (23-10-2007)“…Observations in hemodialysis patients suggest a survival advantage associated with activated vitamin D therapy. Left ventricular (LV) structural and functional…”
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FOXO1-Mediated Activation of Akt Plays a Critical Role in Vascular Homeostasis
Published in Circulation research (07-07-2014)“…RATIONALE:Forkhead box-O transcription factors (FoxOs) transduce a wide range of extracellular signals, resulting in changes in cell survival, cell cycle…”
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Hydrogen Peroxide‐Responsive Nanoparticle Reduces Myocardial Ischemia/Reperfusion Injury
Published in Journal of the American Heart Association (14-11-2016)“…Background During myocardial ischemia/reperfusion (I/R), a large amount of reactive oxygen species (ROS) is produced. In particular, overproduction of hydrogen…”
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The Prominin-1-Derived Peptide Improves Cardiac Function Following Ischemia
Published in International journal of molecular sciences (13-05-2021)“…Myocardial infarction (MI) remains the leading cause of death in the western world. Despite advancements in interventional revascularization technologies, many…”
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Mechanisms and inhibitors of apoptosis in cardiovascular diseases
Published in Current pharmaceutical design (01-06-2011)“…Apoptosis or progress of programmed cell death is a tightly regulated process which plays an important role in various cardiovascular diseases particularly in…”
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RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis
Published in Science signaling (21-10-2014)“…The Ras-related guanosine triphosphatase RhoA mediates pathological cardiac hypertrophy, but also promotes cell survival and is cardioprotective after…”
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Phosphoinositide 3-Kinase(p110α) Plays a Critical Role for the Induction of Physiological, but Not Pathological, Cardiac Hypertrophy
Published in Proceedings of the National Academy of Sciences - PNAS (14-10-2003)“…An unresolved question in cardiac biology is whether distinct signaling pathways are responsible for the development of pathological and physiological cardiac…”
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p -Hydroxybenzyl alcohol-containing biodegradable nanoparticle improves functional blood flow through angiogenesis in a mouse model of hindlimb ischemia
Published in Biomaterials (01-06-2015)“…Abstract Therapeutic angiogenesis has achieved promising results for ischemic diseases or peripheral artery disease in preclinical and early-phase clinical…”
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Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality
Published in The Journal of experimental medicine (12-06-2006)“…Sepsis, the systemic inflammatory response to infection, is a leading cause of morbidity and mortality. The mechanisms of sepsis pathophysiology remain obscure…”
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