Search Results - "KANETO, H"

Marked elevation of plasma procalcitonin levels in patients with diabetic ketoacidosis: A possible useful diagnostic biomarker by Anno, T., Shigemoto, R., Kawasaki, F., Irie, S., Miyashita, N., Kaku, K., Kaneto, H.

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Durability of protective effect of dulaglutide on pancreatic β-cells in diabetic mice: GLP-1 receptor expression is not reduced despite long-term dulaglutide exposure by Kimura, T., Obata, A., Shimoda, M., Hirukawa, H., Kanda-Kimura, Y., Nogami, Y., Kohara, K., Nakanishi, S., Mune, T., Kaku, K., Kaneto, H.

“…It is well-known that chronic exposure to large amounts of ligand leads to downregulation of its receptor. It is not known, however, whether a GLP-1R agonist…”
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Low bilirubin levels are an independent risk factor for diabetic retinopathy and nephropathy in Japanese patients with type 2 diabetes by Hamamoto, S, Kaneto, H, Kamei, S, Shimoda, M, Tawaramoto, K, Kanda-Kimura, Y, Kawasaki, F, Hashiramoto, M, Matsuki, M, Mune, T, Kaku, K

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Beta-cell adaptation and decompensation during the progression of diabetes by WEIR, Gordon C, LAYBUTT, David Ross, KANETO, Hideaki, BONNER-WEIR, Susan, SHARMA, Arun

“…Beta-cell adaptation and decompensation during the progression of diabetes. G C Weir , D R Laybutt , H Kaneto , S Bonner-Weir and A Sharma Joslin Diabetes…”
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Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity by KANETO, H, KAJIMOTO, Y, MIYAGAWA, J.-I, MATSUOKA, T.-A, FUJITANI, Y, UMAYAHARA, Y, HANAFUSA, T, MATSUZAWA, Y, YAMASAKI, Y, HORI, M

“…Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity. H Kaneto , Y Kajimoto , J Miyagawa , T…”
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Increase in cortisol/ACTH ratio after chronic treatment with liraglutide in patients with type 2 diabetes by Kamei, S, Kaneto, H, Tanabe, A, Kinoshita, T, Obata, A, Kimura, T, Hirukawa, H, Tatsumi, F, Shimoda, M, Kohara, K, Anno, Takatoshi, Nakanishi, S, Mune, T, Kaku, K

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Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes by KATAKAMI, N, YAMASAKI, Y, HAYAISHI-OKANO, R, OHTOSHI, K, KANETO, H, MATSUHISA, M, KOSUGI, K, HORI, M

“…Metformin is a well-known oral hypoglycaemic agent and has been commonly used, in combination with sulphonylurea, to treat type 2 diabetes. However, the…”
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Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis by Miyatsuka, T, Kaneto, H, Kajimoto, Y, Hirota, S, Arakawa, Y, Fujitani, Y, Umayahara, Y, Watada, H, Yamasaki, Y, Magnuson, M.A, Miyazaki, J, Hori, M

“…To date, the potency of pancreatic and duodenal homeobox gene 1 (PDX-1) in inducing differentiation into insulin-producing cells has been demonstrated in some…”
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Aldose reductase C-106T gene polymorphism is associated with diabetic retinopathy in Japanese patients with type 2 diabetes by Katakami, N, Kaneto, H, Takahara, M, Matsuoka, T.A, Imamura, K, Ishibashi, F, Kanda, T, Kawai, K, Osonoi, T, Matsuhisa, M, Kashiwagi, A, Kawamori, R, Shimomura, I, Yamasaki, Y

“…Abstract It is likely that the C allele of the polymorphism at position −106 in the promoter of aldose reductase gene, which codes a rate-limiting enzyme of…”
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PO138 MOLECULAR MECHANISM FOR PROTECTIVE EFFECT OF PIOGLITAZONE AND LIRAGLUTIDE ON BETA-CELLS WITH THE PROGRESSION OF DIABETIC MORBIDITY by Kimura, T, Shimoda, M, Hirukawa, H, Okauchi, S, Kohara, K, Kaneto, H, Kaku, K

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Apoptotic cell death triggered by nitric oxide in pancreatic beta-cells by Kaneto, H., Fujii, J., Seo, H. G., Suzuki, K., Matsuoka, T., Nakamura, M., Tatsumi, H., Yamasaki, Y., Kamada, T., Taniguchi, N.

“…Apoptotic cell death triggered by nitric oxide in pancreatic beta-cells. H Kaneto , J Fujii , H G Seo , K Suzuki , T Matsuoka , M Nakamura , H Tatsumi , Y…”
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The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells by Watada, H., Kajimoto, Y., Umayahara, Y., Matsuoka, T., Kaneto, H., Fujitani, Y., Kamada, T., Kawamori, R., Yamasaki, Y.

“…The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells. H Watada , Y…”
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Combined effect of oxidative stress-related gene polymorphisms on atherosclerosis by Katakami, N., Sakamoto, K., Kaneto, H., Matsuhisa, M., Shimizu, I., Ishibashi, F., Osonoi, T., Kashiwagi, A., Kawamori, R., Hori, M., Yamasaki, Y.

“…It is well known that oxidative stress plays critical roles in the pathogenesis of atherosclerosis. In this study, we enrolled 1746 type 2 diabetic subjects,…”
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High prevalence of glucose intolerance in Japanese patients with peripheral arterial disease by Takahara, M, Kaneto, H, Iida, O, Gorogawa, S, Ikeda, M

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Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus by Kaneto, H, Sasaki, S, Yamamoto, H, Itoh, F, Toyota, M, Suzuki, H, Ozeki, I, Iwata, N, Ohmura, T, Satoh, T, Karino, Y, Toyota, J, Satoh, M, Endo, T, Omata, M, Imai, K

“…Inactivation of the p16(INK4A) (p16) tumour suppressor gene by promoter region hypermethylation has been demonstrated not only in many types of tumours,…”
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Oxidative stress induces p21 expression in pancreatic islet cells : possible implication in beta-cell dysfunction by KANETO, H, KAJIMOTO, Y, FUJITANI, Y, MATSUOKA, T, SAKAMOTO, K, MATSUHISA, M, YAMASAKI, Y, HORI, M

“…Prolonged poor glycaemic control in patients with Type II (non-insulin-dependent) diabetes mellitus often causes pancreatic beta-cell dysfunction accompanied…”
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Transforming growth factor β1 T868C gene polymorphism is associated with cerebral infarction in Japanese patients with type 2 diabetes by Katakami, N, Kaneto, H, Osonoi, T, Kawai, K, Ishibashi, F, Imamura, K, Maegawa, H, Kashiwagi, A, Watada, H, Kawamori, R, Shimomura, I, Yamasaki, Y

“…Abstract It is likely that the C allele of the polymorphism at position 29 of the translated sequence of transforming growth factor (TGF)-β1 gene, which codes…”
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Association of soluble CD40 ligand with carotid atherosclerosis in Japanese type 1 diabetic patients by KATAKAMI, N, KANETO, H, KOSUGI, K, HORI, M, YAMASAKI, Y, MATSUHISA, M, MIYATSUKA, T, SAKAMOTO, K, KAWAMORI, D, YOSHIUCHI, K, NAKAMURA, Y, KATO, K, YAMAMOTO, K

“…It has recently been shown that the soluble form of CD40 ligand (sCD40L) interacts with CD40 on vascular cells, leading to a variety of proinflammatory…”
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Increased stress protein ORP150 autoantibody production in Type 1 diabetic patients by Nakatani, Y., Kaneto, H., Hatazaki, M., Yoshiuchi, K., Kawamori, D., Sakamoto, K., Matsuoka, T., Ogawa, S., Yamasaki, Y., Matsuhisa, M.

“…Aims  Various genetic and environmental stresses interfere with protein folding in the endoplasmic reticulum (ER), which leads to the induction of ER stress…”
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Learning/memory processes under stress conditions by Kaneto, Hiroshi

“…Using mice, changes in the learning/memory processes under various stress conditions were investigated in one-trial step-through type passive avoidance…”
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