Search Results - "KANETA, Shigeru"

Possible Mechanisms Underlying Statin-Induced Skeletal Muscle Toxicity in L6 Fibroblasts and in Rats by Itagaki, Mai, Takaguri, Akira, Kano, Seiichiro, Kaneta, Shigeru, Ichihara, Kazuo, Satoh, Kumi

“…3-Hydroxy-3-methylglutaryl CoA reductase inhibitors (statins) are safe and well-tolerated therapeutic drugs. However, they occasionally induce myotoxicity such…”
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All hydrophobic HMG-CoA reductase inhibitors induce apoptotic death in rat pulmonary vein endothelial cells by Kaneta, Shigeru, Satoh, Kumi, Kano, Seiichiro, Kanda, Makoto, Ichihara, Kazuo

“…3-Hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) are effective in patients with hypercholesterolemia to reduce risk of cardiovascular…”
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Simvastatin and Atorvastatin Enhance Hypotensive Effect of Diltiazem in Rats by MARUMO, Hiroshi, SATOH, Kumi, YAMAMOTO, Atsuko, KANETA, Shigeru, ICHIHARA, Kazuo

“…Effects of the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, simvastatin and atorvastatin, on diltiazem-induced hypotension were…”
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The effect of paclitaxel on the progression of polycystic kidney disease in rodents by Martinez, J R, Cowley, B D, Gattone, 2nd, V H, Nagao, S, Yamaguchi, T, Kaneta, S, Takahashi, H, Grantham, J J

“…Woo et al (Nature 368:750-753) reported that parenteral administration of paclitaxel arrested the striking renal enlargement and prolonged life in…”
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コレステロール負荷食ウサギの脂質異常に対するPravastatin先発医薬品と後発医薬品の効果 by 加納, 誠一朗, 田口, 睦, 早勢, 伸正, 金田, 繁, 高栗, 郷, 市原, 和夫, 佐藤, 久美

“…「はじめに」高齢化社会による国民医療費の高騰を是正するため, 政府は高額医療費が伴う心疾患, 脳血管疾患治療などの重篤な疾病に罹患する前に積極的な治療を行うため, 内臓脂肪蓄積を基盤として高脂血症, 糖尿病, 高血圧に関する疾病が2つ以上併発したものをメタボリックシンドロームと診断し,…”
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Renal Carbonic Anhydrase Activity in DBA/2FG-pcy/pcy Mice with Inherited Polycystic Kidney Disease by KANETA, Shigeru, ISHIZUKI, Satoshi, KASAHARA, Masao, NAGAO, Shizuko, TAKAHASHI, Hisahide

“…DBA/2FG-pcy/pcy (D2-pcy) mice are a hereditary murine model of slowly progressive polycystic kidney disease (PKD) and characterized by the persistent excretion…”
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Effects of Minoxidil on Ischemia-Induced Mechanical and Metabolic Dysfunction in Dog Myocardium by Yamamoto, Atsuko, Satoh, Kumi, Ichinosawa, Kenichi, Kaneta, Shigeru, Kano, Seiichiro, Ichihara, Kazuo

“…Effects of minoxidil on ischemia-induced myocardial mechanical and metabolic dysfunction were examined in anesthetized open-chest dogs. A regional portion of…”
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Effects of Radical Scavengers, TA248 and TA276, on Stunned Myocardium in Dogs: Involvement of KATP Channels by Kosugi, Tetsuro, Satoh, Kumi, Kaneta, Shigeru, Aoki, Yasuo, Takagaki, Hidetsugu, Ichihara, Kazuo

“…TA248 (7-(β-D-glucopyranosyloxy)-4-hydroxy-3-octyloxy-2H-1-benzopyran-2-one) and TA276 (sodium 7-hydroxy-3-octyloxy-2H-1-benzopyran-2-one-4-oxide) were newly…”
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Improvement of stunned myocardium in dogs with olmesartan, an angiotensin II type 1 receptor antagonist, is independent of type 2 receptors by Kano, Seiichiro, Satoh, Kumi, Kaneta, Shigeru, Ichihara, Kazuo

“…Olmesartan is a selective angiotensin II type 1 receptor (AT1) antagonist. In pentobarbital-anesthetized open-chest dogs, ischemia/reperfusion was induced by…”
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Effect of the Brand and Generic Medicine of Pravastatin on Dyslipidemia in Rabbits Fed a High Cholesterol Diet by KANO, Seiichiro, TAGUCHI, Mutsumi, HAYASE, Nobumasa, KANETA, Shigeru, TAKAGURI, Akira, ICHIHARA, Kazuo, SATOH, Kumi

“…Mevalotin® containing pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, is the brand medicine and well known to be effective for…”
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Endothelial apoptosis induced by cerivastatin may worsen myocardial contractile function during ischemia/ reperfusion in dogs by Kazuo Ichihara, Atsuko Sampei, Shigeru Kaneta, Kumi Satoh

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Effects of Nebivolol on Ischemia-Induced Metabolic Changes in Dog Hearts by Satoh, Kumi, Takeda, Susumu, Kaneta, Shigeru, Inagami, Tadashi, Ichihara, Kazuo

“…dl-Nebivolol has a β1-adrenergic blocking property and l-nebivolol has an endothelial-dependent vasodilating property, sp that a racemic mixture, δl-nebivolol,…”
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Mouse IgE-mediated paw anaphylaxis in mice and rats by Kaneta, S, Kanbara, H, Fujihira, E, Mitsuya, M

“…Anaphylactic swelling is induced in the hind paws of mice and rats by intravenous challenge of antigen 72 h after subplantar injection of mouse IgE-rich…”
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Effects of radical scavengers, TA248 and TA276, on stunned myocardium in dogs: involvement of K ATP channels by Kosugi, Tetsuro, Satoh, Kumi, Kaneta, Shigeru, Aoki, Yasuo, Takagaki, Hidetsugu, Ichihara, Kazuo

“…TA248 (7-(beta-D-glucopyranosyloxy)-4-hydroxy-3-octyloxy-2H-1-benzopyran-2-one) and TA276 (sodium 7-hydroxy-3-octyloxy-2H-1-benzopyran-2-one-4-oxide) were…”
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