Search Results - "KANEKO, Yasuhiko"

Trim32 facilitates degradation of MYCN on spindle poles and induces asymmetric cell division in human neuroblastoma cells by Izumi, Hideki, Kaneko, Yasuhiko

“…Asymmetric cell division (ACD) is a physiologic process during development and tissue homeostasis. ACD produces two unequal daughter cells: one has…”
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Evidence of asymmetric cell division and centrosome inheritance in human neuroblastoma cells by Izumi, Hideki, Kaneko, Yasuhiko

“…Asymmetric cell division (ACD) is believed to be a physiological event that occurs during development and tissue homeostasis in a large variety of organisms…”
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The Role of MYCN in Symmetric vs. Asymmetric Cell Division of Human Neuroblastoma Cells by Izumi, Hideki, Kaneko, Yasuhiko, Nakagawara, Akira

“…Asymmetric cell division (ACD) is an important physiological event in the development of various organisms and maintenance of tissue homeostasis. ACD produces…”
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Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region by Izumi, Hideki, Li, Yuanyuan, Shibaki, Masami, Mori, Daisuke, Yasunami, Michio, Sato, Seiji, Matsunaga, Hisashi, Mae, Takao, Kodama, Kenji, Kamijo, Takehiko, Kaneko, Yasuhiko, Nakagawara, Akira

“…CD133 is a transmembranous protein that mainly localises to the plasma membrane in haematopoietic and neural stem cells as well as cancer stem cells. Although…”
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Molecular Regulation of Autophagy and Asymmetric Cell Division by Cancer Stem Cell Marker CD133 by Izumi, Hideki, Kaneko, Yasuhiko, Nakagawara, Akira

“…CD133, also called prominin-1, is widely known as a cancer stem cell marker, and its high expression correlates with a poor prognosis in many cancers. CD133…”
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Analysis of Asymmetric Cell Division Using Human Neuroblastoma Cell Lines as a Model System by Izumi, Hideki, Kaneko, Yasuhiko, Nakagawara, Akira

“…Neuroblastoma is one of the most common childhood solid tumors and develops from neural stem cells that normally comprise the embryonic structure termed the…”
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Outcome of renal tumors registered in Japan Wilms Tumor Study‐2 (JWiTS‐2): A report from the Japan Children's Cancer Group (JCCG) by Koshinaga, Tsugumichi, Takimoto, Tetsuya, Oue, Takaharu, Okita, Hajime, Tanaka, Yukichi, Nozaki, Miwako, Tsuchiya, Kunihiko, Inoue, Eisuke, Haruta, Masayuki, Kaneko, Yasuhiko, Fukuzawa, Masahiro

“…Background Japan Wilms Tumor Study‐2 (JWiTS‐2) mandated central pathology review for all case registrations. The study aimed to compare the outcomes of…”
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Kasumi leukemia cell lines: characterization of tumor genomes with ethnic origin and scales of genomic alterations by Kasai, Fumio, Asou, Hiroya, Ozawa, Midori, Kobayashi, Kazuhiko, Kuramitsu, Hiroyuki, Satoh, Motonobu, Kohara, Arihiro, Kaneko, Yasuhiko, Kawamura, Machiko

“…Kasumi-1 has played an important role in an experimental model with t(8;21) translocation, which is a representative example of leukemia cell lines. However,…”
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Frequent breakpoints of focal deletion and uniparental disomy in 22q11.1 or 11.2 segmental duplication region reveal distinct tumorigenesis in rhabdoid tumor of the kidney by Haruta, Masayuki, Arai, Yasuhito, Okita, Hajime, Tanaka, Yukichi, Takimoto, Tetsuya, Kamijo, Takehiko, Oue, Takaharu, Souzaki, Ryota, Taguchi, Tomoaki, Kuwahara, Yasumichi, Chin, Motoaki, Nakadate, Hisaya, Hiyama, Eiso, Ishida, Yasushi, Koshinaga, Tsugumichi, Kaneko, Yasuhiko

“…SMARCB1 is mutated in most rhabdoid tumors (RTs) developing in the kidney (RTK) and various other organs. Focal deletions found in patients with 22q11.2…”
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Genomic analysis-integrated whole-exome sequencing of neuroblastomas identifies genetic mutations in axon guidance pathway by Li, Yuanyuan, Ohira, Miki, Zhou, Yong, Xiong, Teng, Luo, Wen, Yang, Chao, Li, Xiangchun, Gao, Zhibo, Zhou, Rui, Nakamura, Yohko, Kamijo, Takehiko, Kaneko, Yasuhiko, Taketani, Takeshi, Ueyama, Junichi, Tajiri, Tatsuro, Zhang, Hongyan, Wang, Jian, Yang, Huanming, Yin, Ye, Nakagawara, Akira

“…Neuroblastoma (NB) is a childhood solid malignant tumor originating from precursor cells of the peripheral nervous system. We have previously established a…”
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Clinical prognostic value of DNA methylation in hepatoblastoma: Four novel tumor suppressor candidates by Honda, Shohei, Minato, Masashi, Suzuki, Hiromu, Fujiyoshi, Masato, Miyagi, Hisayuki, Haruta, Masayuki, Kaneko, Yasuhiko, Hatanaka, Kanako C., Hiyama, Eiso, Kamijo, Takehiko, Okada, Tadao, Taketomi, Akinobu

“…Hepatoblastoma (HB) is very rare but the most common malignant neoplasm of the liver occurring in children. Despite improvements in therapy, outcomes for…”
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Blastemal predominant type Wilms tumor in Japan: Japan Children's Cancer Group by Koshinaga, Tsugumichi, Takimoto, Tetsuya, Okita, Hajime, Tanaka, Yukichi, Inoue, Eisuke, Oue, Takaharu, Nozaki, Miwako, Tsuchiya, Kunihiko, Haruta, Masayuki, Kaneko, Yasuhiko, Fukuzawa, Masahiro

“…Background Persistence of blastemal components after chemotherapy is a marker of poor outcome in Wilms tumor (WT). Recent reports from local Japanese areas…”
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RASSF1A methylation may have two biological roles in neuroblastoma tumorigenesis depending on the ploidy status and age of patients by Haruta, Masayuki, Kamijo, Takehiko, Nakagawara, Akira, Kaneko, Yasuhiko

“…Abstract RASSF1A methylation was frequent in neuroblastomas found in infants by mass-screening or infants and children diagnosed clinically, whereas CASP8 and…”
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NM23 downregulation and lysophosphatidic acid receptor EDG2/lpa1 upregulation during myeloid differentiation of human leukemia cells by Okabe-Kado, Junko, Hagiwara-Watanabe, Yuki, Niitsu, Nozomi, Kasukabe, Takashi, Kaneko, Yasuhiko

“…A common mechanism for inhibition of leukemia cell myeloid differentiation and breast cancer cell motility involving NM23 and EDG2. [Display omitted] •NM23…”
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Bilateral Wilms tumors treated according to the Japan Wilms Tumor Study Group protocol by Oue, Takaharu, Koshinaga, Tsugumichi, Okita, Hajime, Kaneko, Yasuhiko, Hinotsu, Shiro, Fukuzawa, Masahiro

“…Background The introduction of multimodal therapy has improved the survival rate of bilateral Wilms tumors (BWT); however, the results are still not…”
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Combined Genetic and Chromosomal Characterization of Wilms Tumors Identifies Chromosome 12 Gain as a Potential New Marker Predicting a Favorable Outcome by Haruta, Masayuki, Arai, Yasuhito, Okita, Hajime, Tanaka, Yukichi, Takimoto, Tetsuya, Sugino, Ryuichi P., Yamada, Yasuhiro, Kamijo, Takehiko, Oue, Takaharu, Fukuzawa, Masahiro, Koshinaga, Tsugumichi, Kaneko, Yasuhiko

“…To identify prognostic factors, array CGH (aCGH) patterns and mutations in WT1 and 9 other genes were analyzed in 128 unilateral Wilms tumors (WTs). Twenty…”
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Extracellular NM23 protein promotes the growth and survival of primary cultured human acute myelogenous leukemia cells by Okabe‐Kado, Junko, Kasukabe, Takashi, Honma, Yoshio, Kobayashi, Hirofumi, Maseki, Nobuo, Kaneko, Yasuhiko

“…An elevated serum level of NM23‐H1 protein is found in acute myelogenous leukemia (AML), and predicts a poor treatment outcome in AML patients. To investigate…”
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Ellagic acid, a natural polyphenolic compound, induces apoptosis and potentiates retinoic acid-induced differentiation of human leukemia HL-60 cells by Hagiwara, Yuki, Kasukabe, Takashi, Kaneko, Yasuhiko, Niitsu, Nozomi, Okabe-Kado, Junko

“…All-trans retinoic acid (ATRA) is a standard drug used for differentiation therapy in acute promyelocytic leukemia. To potentiate this therapy, we examined the…”
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AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma by Namiki, Takeshi, Tanemura, Atsushi, Valencia, Julio C, Coelho, Sergio G, Passeron, Thierry, Kawaguchi, Masakazu, Vieira, Wilfred D, Ishikawa, Masashi, Nishijima, Wataru, Izumo, Toshiyuki, Kaneko, Yasuhiko, Katayama, Ichiro, Yamaguchi, Yuji, Yin, Lanlan, Polley, Eric C, Liu, Hongfang, Kawakami, Yutaka, Eishi, Yoshinobu, Takahashi, Eishi, Yokozeki, Hiroo, Hearing, Vincent J

“…The identification of genes that participate in melanomagenesis should suggest strategies for developing therapeutic modalities. We used a public array…”
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Management of pediatric renal tumor: Past and future trials of the Japan Wilms Tumor Study Group by Oue, Takaharu, Fukuzawa, Masahiro, Koshinaga, Tsugumichi, Okita, Hajime, Nozaki, Miwako, Chin, Motoki, Kaneko, Yasuhiko, Tanaka, Yukichi, Haruta, Masayuki, Tsuchiya, Kunihiko, Kuwajima, Shigeko, Takimoto, Tetsuya

“…The Japan Wilms Tumor Study group (JWiTS) was founded in 1996 to improve outcomes for children with renal tumor in Japan, and a nationwide multicenter…”
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