Search Results - "KANEHIRO, Arihiko"

TOPICS 2017 IN BRONCHIAL ASTHMA by Kanehiro, Arihiko

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Dramatic Response to Tezepelumab as an Initial Biologic Agent for Refractory Asthma Associated with Type 2 and Non-type 2 Traits by Minami, Daisuke, Hosoya, Takeshi, Hosoya, Masaharu, Nagano, Akichika, Nakajima, Yasuhiro, Miyahara, Nobuaki, Kanehiro, Arihiko

“…A 74-year-old Japanese woman presented with a 45-year history of refractory asthma. She had been treated with inhaled corticosteroids, a long-acting…”
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A retinoid X receptor partial agonist attenuates pulmonary emphysema and airway inflammation by Morichika, Daisuke, Miyahara, Nobuaki, Fujii, Utako, Taniguchi, Akihiko, Oda, Naohiro, Senoo, Satoru, Kataoka, Mikio, Tanimoto, Mitsune, Kakuta, Hiroki, Kiura, Katsuyuki, Maeda, Yoshinobu, Kanehiro, Arihiko

“…Retinoid X receptors (RXRs) are members of the nuclear receptor (NR) superfamily that mediate signalling by 9-cis retinoic acid, a vitamin A derivative. RXRs…”
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Severe asthma concomitant with allergic bronchopulmonary aspergillosis successfully treated with mepolizumab by Oda, Naohiro, Miyahara, Nobuaki, Senoo, Satoru, Itano, Junko, Taniguchi, Akihiko, Morichika, Daisuke, Fujii, Utako, Maeda, Yoshinobu, Kiura, Katsuyuki, Kanehiro, Arihiko

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Requirement for neuropeptide Y in the development of type 2 responses and allergen-induced airway hyperresponsiveness and inflammation by Oda, Naohiro, Miyahara, Nobuaki, Taniguchi, Akihiko, Morichika, Daisuke, Senoo, Satoru, Fujii, Utako, Itano, Junko, Gion, Yuka, Kiura, Katsuyuki, Kanehiro, Arihiko, Maeda, Yoshinobu

“…Neuropeptide Y (NPY) is a neurotransmitter that is widely expressed in the brain and peripheral nervous system. Various immune cells express the NPY Y…”
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Loss of IL-33 enhances elastase-induced and cigarette smoke extract-induced emphysema in mice by Morichika, Daisuke, Taniguchi, Akihiko, Oda, Naohiro, Fujii, Utako, Senoo, Satoru, Itano, Junko, Kanehiro, Arihiko, Kitaguchi, Yoshiaki, Yasuo, Masanori, Hanaoka, Masayuki, Satoh, Takashi, Akira, Shizuo, Kiura, Katsuyuki, Maeda, Yoshinobu, Miyahara, Nobuaki

“…IL-33, which is known to induce type 2 immune responses via group 2 innate lymphoid cells, has been reported to contribute to neutrophilic airway inflammation…”
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Nintedanib can be used safely and effectively for idiopathic pulmonary fibrosis with predicted forced vital capacity ≤ 50%: A multi-center retrospective analysis by Senoo, Satoru, Miyahara, Nobuaki, Taniguchi, Akihiko, Oda, Naohiro, Itano, Junko, Higo, Hisao, Hara, Naofumi, Watanabe, Hiromi, Kano, Hirohisa, Suwaki, Toshimitsu, Fuchimoto, Yasuko, Kajimoto, Kazuhiro, Ichikawa, Hirohisa, Kudo, Kenichiro, Shibayama, Takuo, Tanimoto, Yasushi, Kuyama, Shoichi, Kanehiro, Arihiko, Maeda, Yoshinobu, Kiura, Katsuyuki

“…Background Nintedanib is a multi-kinase inhibitor approved for idiopathic pulmonary fibrosis (IPF); however, its efficacy and safety for patients with IPF and…”
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IL-23 Is Essential for the Development of Elastase-Induced Pulmonary Inflammation and Emphysema by Fujii, Utako, Miyahara, Nobuaki, Taniguchi, Akihiko, Waseda, Koichi, Morichika, Daisuke, Kurimoto, Etsuko, Koga, Hikari, Kataoka, Mikio, Gelfand, Erwin W, Cua, Daniel J, Yoshimura, Akihiko, Tanimoto, Mitsune, Kanehiro, Arihiko

“…We recently reported that IL-17A plays a critical role in the development of porcine pancreatic elastase (PPE)-induced emphysema. The proliferation of T-helper…”
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BRONCHIAL ASTHMA AND LIFE ENVIRONMENT by Kanehiro, Arihiko

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Effect of a retinoid X receptor partial agonist on airway inflammation and hyperresponsiveness in a murine model of asthma by Fujii, Utako, Miyahara, Nobuaki, Taniguchi, Akihiko, Oda, Naohiro, Morichika, Daisuke, Murakami, Etsuko, Nakayama, Hikari, Waseda, Koichi, Kataoka, Mikio, Kakuta, Hiroki, Tanimoto, Mitsune, Kanehiro, Arihiko

“…Retinoid X receptors (RXRs) are members of the nuclear receptor (NR) superfamily that mediate signaling by 9-cis retinoic acid, a vitamin A (retinol)…”
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IL-17A is essential to the development of elastase-induced pulmonary inflammation and emphysema in mice by Kurimoto, Etsuko, Miyahara, Nobuaki, Kanehiro, Arihiko, Waseda, Koichi, Taniguchi, Akihiko, Ikeda, Genyo, Koga, Hikari, Nishimori, Hisakazu, Tanimoto, Yasushi, Kataoka, Mikio, Iwakura, Yoichiro, Gelfand, Erwin W, Tanimoto, Mitsune

“…Pulmonary emphysema is characterized by alveolar destruction and persistent inflammation of the airways. Although IL-17A contributes to many chronic…”
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Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway responses by Koga, Hikari, Miyahara, Nobuaki, Fuchimoto, Yasuko, Ikeda, Genyo, Waseda, Koichi, Ono, Katsuichiro, Tanimoto, Yasushi, Kataoka, Mikio, Gelfand, Erwin W, Tanimoto, Mitsune, Kanehiro, Arihiko

“…Chronic asthma is often associated with neutrophilic infiltration in the airways. Neutrophils contain elastase, a potent secretagogue in the airways,…”
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Pneumocystis Pneumonia Concomitant with Ectopic ACTH Syndrome Caused by a Large Cell Neuroendocrine Carcinoma of the Thymus by Oda, Naohiro, Miyahara, Nobuaki, Tabata, Masahiro, Minami, Daisuke, Ninomiya, Kiichiro, Kanehiro, Arihiko, Komatsubara, Motoshi, Inagaki, Kenichi, Tanimoto, Mitsune, Kiura, Katsuyuki

“…We herein report the case of a 44-year-old man who was diagnosed with pneumocystis pneumonia (PCP) concomitant with ectopic adrenocorticotropic hormone (ACTH)…”
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Contrasting roles for the receptor for advanced glycation end-products on structural cells in allergic airway inflammation vs. airway hyperresponsiveness by Taniguchi, Akihiko, Miyahara, Nobuaki, Waseda, Koichi, Kurimoto, Etsuko, Fujii, Utako, Tanimoto, Yasushi, Kataoka, Mikio, Yamamoto, Yasuhiko, Gelfand, Erwin W, Yamamoto, Hiroshi, Tanimoto, Mitsune, Kanehiro, Arihiko

“…The receptor for advanced glycation end-products (RAGE) is a multiligand receptor that belongs to the immunoglobulin superfamily. RAGE is reported to be…”
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Use of a highly sensitive lung cancer compact panel to detect KRAS G12D in the wash fluid from a lung tumor: A case report by Minami, Daisuke, Takigawa, Nagio, Nakajima, Yasuhiro, Miyahara, Nobuaki, Mizumori, Yasuyuki, Ueda, Mitsuhiro, Nakamura, Seiji, Suzuki, Fumihiko, Sato, Yoshiharu, Morikawa, Kei, Kanehiro, Arihiko

“…Here, we report a case of a pulmonary invasive mucinous adenocarcinoma harboring KRAS G12D, diagnosed from tumor samples containing a very small amount of…”
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Protective Effects of Bisoprolol against Acute Exacerbation in Moderate-to-Severe Chronic Obstructive Pulmonary Disease by Taniguchi, Akihiko, Miyahara, Nobuaki, Oda, Naohiro, Morichika, Daisuke, Ichihara, Eiki, Oze, Isao, Tanimoto, Yasushi, Ichikawa, Hirohisa, Fujii, Utako, Tanimoto, Mitsune, Kanehiro, Arihiko, Kiura, Katsuyuki

“…Although recent retrospective studies suggested that the use of β-blockers appears to help improve the mortality rate and decrease the rate of exacerbation in…”
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Deterioration of high-resolution computed tomography findings predicts disease progression after initial decline in forced vital capacity in idiopathic pulmonary fibrosis patients treated with pirfenidone by Higo, Hisao, Miyahara, Nobuaki, Taniguchi, Akihiko, Senoo, Satoru, Itano, Junko, Watanabe, Hiromi, Oda, Naohiro, Kayatani, Hiroe, Ichikawa, Hirohisa, Shibayama, Takuo, Kajimoto, Kazuhiro, Tanimoto, Yasushi, Kanehiro, Arihiko, Maeda, Yoshinobu, Kiura, Katsuyuki

“…Pirfenidone suppresses the decline of forced vital capacity (FVC) in patients with idiopathic pulmonary fibrosis (IPF). However, IPF progresses in some…”
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Heerfordt's Syndrome Associated with a High Fever and Elevation of TNF-α by Makimoto, Go, Miyahara, Nobuaki, Yoshikawa, Mao, Taniguchi, Akihiko, Kanehiro, Arihiko, Tanimoto, Mitsune, Kiura, Katsuyuki

“…Heerfordt's syndrome is a rare manifestation of sarcoidosis and is defined as a combination of facial palsy, parotid swelling, and uveitis, associated with a…”
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Effect of fudosteine, a cysteine derivative, on airway hyperresponsiveness, inflammation, and remodeling in a murine model of asthma by Ueno-Iio, Tomoe, Shibakura, Misako, Iio, Koji, Tanimoto, Yasushi, Kanehiro, Arihiko, Tanimoto, Mitsune, Kataoka, Mikio

“…Fudosteine is a cysteine derivative that is used as an expectorant in chronic bronchial inflammatory disorders. It has been shown to decrease the number of…”
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Invasive Mucinous Adenocarcinoma Mimicking Organizing Pneumonia Associated with Mycobacterium fortuitum Infection by Morichika, Daisuke, Miyahara, Nobuaki, Hotta, Katsuyuki, Okamoto, Yoshiko, Minami, Daisuke, Irie, Masahiro, Tanimoto, Yasushi, Kanehiro, Arihiko, Tanimoto, Mitsune, Kiura, Katsuyuki

“…We herein report the case of a 68-year-old man diagnosed with invasive mucinous adenocarcinoma of the lungs. Chest computed tomography showed subpleural…”
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