Search Results - "KANDLIKAR, Sachin"

Splanchnic sympathetic nerves in the development of mild DOCA-salt hypertension by Kandlikar, Sachin S, Fink, Gregory D

“…We previously reported that mild deoxycorticosterone acetate (DOCA)-salt hypertension develops in the absence of generalized sympathoexcitation. However,…”
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Mild DOCA-salt hypertension: sympathetic system and role of renal nerves by Kandlikar, Sachin S, Fink, Gregory D

“…Excess sympathetic nervous system activity (SNA) is linked to human essential and experimental hypertension. To test whether sympathetic activation is…”
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Requirement for Functional BK Channels in Maintaining Oscillation in Venomotor Tone Revealed by Species Differences in Expression of the β1 Accessory Subunits by Xu, Hui, Kandlikar, Sachin S, Westcott, Erika B, Fink, Gregory D, Galligan, James J

“…ABSTRACTWe determined the possible role of large-conductance Ca-activated K (BK) channels in regulation of venous tone in small capacitance veins and blood…”
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BK channel function, venous tone and blood pressure regulation by Xu, Hui, Kandlikar, Sachin

“…Abstract only Impaired large‐conductance Ca 2+ ‐activated K + (BK) channel function in smooth muscle cells (SMC) causes an increase in intracellular Ca 2+ and…”
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Lumbar sympathectomy does not attenuate the development of mild DOCA‐salt hypertension by Kandlikar, Sachin, Osborn, John, Fink, Gregory

“…Increased sympathetic nervous activity (SNA), responsible for the development and maintenance of hypertension, is more prominent in some vascular beds than…”
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Effect of diet on the progression of diabetic nephropathy in db/db mice by Kandlikar, Sachin S, Joly, Kristin M, Horn, Todd R, Glascock, Chris G, Plato, Craig F

“…Abstract only Diabetic nephropathy (DN) is the leading cause of end stage renal disease. Severity of diabetes and its complications are influenced by dietary…”
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Nrf2 antioxidant pathway activation attenuates renal ischemia/reperfusion (I/R)‐induced alterations in biomarkers by Richards, Toni L., Ida, Kevin K., Horn, Todd R., Kandlikar, Sachin S., Plato, Craig F.

“…Abstract only Acute kidney injury (AKI) secondary to acute renal ischemia is associated with high mortality and morbidity. Oxidative stress is a key component…”
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Early sympathetic denervation of splanchnic organs significantly attenuates hypertension and stroke development in stroke‐prone spontaneously hypertensive rats by Kandlikar, Sachin, Dorrance, Anne M, Fink, Gregory

“…Abstract only Human and experimental studies have shown that splanchnic sympathetic nervous activity (SNA) is important in the development and maintenance of…”
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Exposure to Acute Intermittent Hypoxia (IH) Prolongs Sympathoexcitatory and Pressor Responses Evoked by NMDA in the Hypothalamic Paraventricular Nucleus (PVN) by Kandlikar, Sachin S., Andrade, Mary Ann, Calderon, Alfredo S., Toney, Glenn M.

“…Abstract only Exposure of rats to acute IH induces long term facilitation (LTF) of sympathetic nerve activity (SNA). Neurons of PVN subserve cardio‐respiratory…”
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The splanchnic sympathetic nervous system in DOCA‐salt hypertension by Kandlikar, Sachin, King, Andrew, Fink, Gregory

“…Whole body venous tone increases in DOCA‐salt hypertension (HTN) and is mediated in part by sympathetic nervous system (SNS) activation. The capacitance…”
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Sympathetic activation in the development of DOCA‐salt hypertension by Kandlikar, Sachin, King, Andrew J, Novotny, Martin, Fink, Gregory

“…Abstract only Indirect evidence indicates that sympathetic activity (SNA) is increased in DOCA‐salt hypertension. Total body norepinephrine (NE) spillover…”
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Sympathetic nervous system in the development of mild DOCA-salt hypertension by Kandlikar, Sachin Sudhir

“…Understanding mechanisms leading to essential hypertension has been challenging even after several decades of research. Long-term regulation of arterial…”
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Cloning and expression analysis of two novel paraflagellar rod domain genes found in Trypanosoma cruzi by CLARK, April K, KOVTUNOVYCH, Gennadiy, KANDLIKAR, Sachin, LAL, Shailesh, STRYKER, Gabrielle A

“…The eukaryotic flagellum is one of the most complex macromolecular structures found in cells, containing more than 250 proteins. One unique structure in the…”
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Sympathetic nervous system in the development of mild DOCA-salt hypertension by Kandlikar, Sachin Sudhir

“…Understanding mechanisms leading to essential hypertension has been challenging even after several decades of research. Long-term regulation of arterial…”
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An examination of the effect of decaying exponential pulse electric fields on cell mortality in murine spleenocytes, hybridomas, and human natural killer cells by Kandlikar, Sachin, Oakley, Barbara, Hanna, Darrin, Stryker, Gabrielle

“…This work describes the percentage cell lysis produced by exponentially decaying electric field pulses of varying amplitudes and time constants. Three…”
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Detection of Vesicular Stomatitis Virus using a Capacitive Immunosensor by Hanna, D.M., Gross, B.A., Kandlikar, S., Lempicki, E., Oakley, B.A., Stryker, G.A.

“…This paper describes the detection of vesicular stomatitis virus using a novel capacitive immunosensor technology, whereby the respective antibodies for the…”
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An examination of the effect of an AC pulsed electric field on cell mortality in SWLA-2 hybridomas by Gross, Brooks, Kandlikar, Sachin, Oakley, Barbara, Hanna, Darrin, Rusek, Andrew, Stryker, Gabrielle

“…This work describes the initial experimental setup and results involving the percentage cell lysis in SWLA-2 murine hybridomas produced by AC electric field…”
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Cell Lysis in SWLA-2 Hybridomas due to 1 kHz AC Electric Fields by Oakley, B.A., Hanna, D.M., Kandlikar, S., Gross, B., Stryker, G.A.

“…This paper describes results involving the percentage cell lysis of SWLA-2 murine hybridomas produced by AC electric field pulses at 1 kHz with pulse widths…”
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