Search Results - "KANDA, TATSUO"

Molecular Mechanism of Chronic Viral and Non-Viral Liver Diseases by Kanda, Tatsuo

“…In this Special Issue, "Molecular Mechanism of Chronic Viral and Non-viral Liver Diseases", invaluable articles have been published [...]…”
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No additive effects of peginterferon on the short-term improvement of liver histology by entecavir monotherapy in chronic hepatitis B patients by Kanda, Tatsuo

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Molecular Mechanisms Driving Progression of Liver Cirrhosis towards Hepatocellular Carcinoma in Chronic Hepatitis B and C Infections: A Review by Kanda, Tatsuo, Goto, Taichiro, Hirotsu, Yosuke, Moriyama, Mitsuhiko, Omata, Masao

“…Almost all patients with hepatocellular carcinoma (HCC), a major type of primary liver cancer, also have liver cirrhosis, the severity of which hampers…”
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Exosomes and Hepatocellular Carcinoma: From Bench to Bedside by Sasaki, Reina, Kanda, Tatsuo, Yokosuka, Osamu, Kato, Naoya, Matsuoka, Shunichi, Moriyama, Mitsuhiko

“…As hepatocellular carcinoma (HCC) usually occurs in the background of cirrhosis, which is an end-stage form of liver diseases, treatment options for advanced…”
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Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma by Kanda, Tatsuo, Goto, Taichiro, Hirotsu, Yosuke, Masuzaki, Ryota, Moriyama, Mitsuhiko, Omata, Masao

“…Nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), causes hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC)…”
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Apoptosis and non-alcoholic fatty liver diseases by Kanda, Tatsuo, Matsuoka, Shunichi, Yamazaki, Motomi, Shibata, Toshikatsu, Nirei, Kazushige, Takahashi, Hiroshi, Kaneko, Tomohiro, Fujisawa, Mariko, Higuchi, Teruhisa, Nakamura, Hitomi, Matsumoto, Naoki, Yamagami, Hiroaki, Ogawa, Masahiro, Imazu, Hiroo, Kuroda, Kazumichi, Moriyama, Mitsuhiko

“…The number of patients with nonalcoholic fatty liver diseases (NAFLD) including nonalcoholic steatohepatitis (NASH), has been increasing. NASH causes cirrhosis…”
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Liver Diseases: From Bench to Bedside by Kanda, Tatsuo, Sasaki-Tanaka, Reina, Terai, Shuji

“…The human genome encodes at least 500 protein kinases, and among them, there are at least 90 tyrosine kinases [...]…”
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Direct-acting antiviral agents against hepatitis C virus and lipid metabolism by Kanda, Tatsuo, Moriyama, Mitsuhiko

“…Hepatitis C virus(HCV) infection induces steatosis and is accompanied by multiple metabolic alterations including hyperuricemia, reversible hypocholesterolemia…”
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Androgen receptor signaling in hepatocellular carcinoma and pancreatic cancers by Kanda, Tatsuo, Jiang, Xia, Yokosuka, Osamu

“…Hepatocellular carcinoma(HCC)and pancreatic cancer remain difficult to treat,and despite the ongoing development of new treatments,the overall survival rate…”
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Hepatitis C virus NS5A inhibitors and drug resistance mutations by Nakamoto, Shingo, Kanda, Tatsuo, Wu, Shuang, Shirasawa, Hiroshi, Yokosuka, Osamu

“…Some direct-acting antiviral agents for hepatitis C virus(HCV),such as telaprevir and boceprevir have been available since 2011.It was reported that HCV NS5A…”
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Hepatitis A Virus Infection and Molecular Research by Kanda, Tatsuo, Sasaki-Tanaka, Reina, Nakamoto, Shingo

“…Hepatitis A virus (HAV) infection is a major cause of acute viral hepatitis globally, which can occasionally lead to acute liver failure (ALF) and…”
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Amantadine and Rimantadine Inhibit Hepatitis A Virus Replication through the Induction of Autophagy by Sasaki-Tanaka, Reina, Shibata, Toshikatsu, Moriyama, Mitsuhiko, Okamoto, Hiroaki, Kogure, Hirofumi, Kanda, Tatsuo

“…Hepatitis A virus (HAV) infection is a major cause of acute viral hepatitis worldwide. Furthermore, HAV causes acute liver failure or acute-on-chronic liver…”
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Akt inhibitor augments anti-proliferative efficacy of a dual mTORC1/2 inhibitor by FOXO3a activation in p53 mutated hepatocarcinoma cells by Patra, Tapas, Meyer, Keith, Ray, Ratna B., Kanda, Tatsuo, Ray, Ranjit

“…Hepatocellular carcinoma (HCC) is one of the most common malignancy-related deaths. p53 mutation in HCC associates with worse clinicopathologic features…”
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Inflammation of the liver, HCC development and HCC establishment by Kanda, Tatsuo, Sasaki-Tanaka, Reina, Terai, Shuji

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Nonalcoholic fatty liver disease and hepatic cirrhosis: comparison with viral hepatitis-associated steatosis by Haga, Yuki, Kanda, Tatsuo, Sasaki, Reina, Nakamura, Masato, Nakamoto, Shingo, Yokosuka, Osamu

“…Nonalcoholic fatty liver disease(NAFLD) including nonalcoholic steatohepatitis(NASH) is globally increasing and has become a world-wide health problem. Chronic…”
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Favipiravir Inhibits Hepatitis A Virus Infection in Human Hepatocytes by Sasaki-Tanaka, Reina, Shibata, Toshikatsu, Okamoto, Hiroaki, Moriyama, Mitsuhiko, Kanda, Tatsuo

“…Hepatitis A virus (HAV) is a causative agent of acute hepatitis and can occasionally induce acute liver failure. However, specific potent anti-HAV drug is not…”
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Molecular Changes in Relation to Alcohol Consumption and Hepatocellular Carcinoma by Sasaki-Tanaka, Reina, Ray, Ranjit, Moriyama, Mitsuhiko, Ray, Ratna B, Kanda, Tatsuo

“…Alcohol is the one of the major causes of liver diseases and promotes liver cirrhosis and hepatocellular carcinoma (HCC). In hepatocytes, alcohol is converted…”
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Efficacy and safety of sofosbuvir–velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial by Takehara, Tetsuo, Sakamoto, Naoya, Nishiguchi, Shuhei, Ikeda, Fusao, Tatsumi, Tomohide, Ueno, Yoshiyuki, Yatsuhashi, Hiroshi, Takikawa, Yasuhiro, Kanda, Tatsuo, Sakamoto, Minoru, Tamori, Akihiro, Mita, Eiji, Chayama, Kazuaki, Zhang, Gulan, De-Oertel, Shampa, Dvory-Sobol, Hadas, Matsuda, Takuma, Stamm, Luisa M., Brainard, Diana M., Tanaka, Yasuhito, Kurosaki, Masayuki

“…Background In Japan, hepatitis C virus (HCV)-infected patients with decompensated cirrhosis currently have no treatment options. In this Phase 3 study, we…”
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Knockdown of Mitogen-Activated Protein Kinase Kinase 3 Negatively Regulates Hepatitis A Virus Replication by Kanda, Tatsuo, Sasaki-Tanaka, Reina, Masuzaki, Ryota, Matsumoto, Naoki, Okamoto, Hiroaki, Moriyama, Mitsuhiko

“…Zinc chloride is known to be effective in combatting hepatitis A virus (HAV) infection, and zinc ions seem to be especially involved in Toll-like receptor…”
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Tumor stiffness measurement using magnetic resonance elastography can predict recurrence and survival after curative resection of hepatocellular carcinoma by Abe, Hayato, Shibutani, Kazu, Yamazaki, Shintaro, Kanda, Tatsuo, Moriyama, Mitsuhiko, Okada, Masahiro, Sugitani, Masahiko, Tsuji, Shingo, Takayama, Tadatoshi, Okamura, Yukiyasu

“…Tumor stiffness measurement using magnetic resonance elastography can assess tumor mechanical properties and predict hepatocellular carcinoma recurrence. This…”
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