Search Results - "KANBE, Yoshitake"

Discovery of thiochroman derivatives bearing a carboxy-containing side chain as orally active pure antiestrogens by Kanbe, Yoshitake, Kim, Myung-Hwa, Nishimoto, Masahiro, Ohtake, Yoshihito, Tsunenari, Toshiaki, Taniguchi, Kenji, Ohizumi, Iwao, Kaiho, Shin-ichi, Nabuchi, Yoshiaki, Kawata, Setsu, Morikawa, Kazumi, Jo, Jae-Chon, Kwon, Hee-An, Lim, Hyun-Suk, Kim, Hak-Yeop

“…Thiochroman derivatives bearing the carboxy moiety in the long side chain exhibited remarkable antiestrogen activity when administered orally. In order to…”
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Thiochroman Derivative CH4986399, A New Nonsteroidal Estrogen Receptor Down-regulator, Is Effective in Breast Cancer Models by YONEYA, Takaaki, TANIGUCHI, Kenji, NAKAMURA, Ryo, TSUNENARI, Toshiaki, OHIZUMI, Iwao, KANBE, Yoshitake, MORIKAWA, Kazumi, KAIHO, Shin-Ichi, YAMADA-OKABE, Hisafumi

“…Tamoxifen, a selective estrogen receptor modulator, and fulvestrant, a selective estrogen receptor down-regulator (SERD), are now available for estrogen…”
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Effects of CH4893237, a new orally active estrogen receptor downregulator, on breast cancer xenograft models with low serum estrogen levels by YONEYA, Takaaki, TSUNENARI, Toshiaki, TANIGUCHI, Kenji, KANBE, Yoshitake, MORIKAWA, Kazumi, YAMADA-OKABE, Hisafumi, YEON-HOLEE, LEE, Mee-Hyun, KWON, Lae-Sung

“…We compared the antitumor efficacy and estrogen receptor (ER) degradation of CH4893237, a new orally active selective ER downregulator, with fulvestrant and…”
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Discovery of thiochroman and chroman derivatives as pure antiestrogens and their structure–activity relationship by Kanbe, Yoshitake, Kim, Myung-Hwa, Nishimoto, Masahiro, Ohtake, Yoshihito, Kato, Nobuaki, Tsunenari, Toshiaki, Taniguchi, Kenji, Ohizumi, Iwao, Kaiho, Shin-ichi, Morikawa, Kazumi, Jo, Jae-Chon, Lim, Hyun-Suk, Kim, Hak-Yeop

“…In order to develop pure antiestrogens, a series of 7-hydroxy-3-(4-hydroxyphenyl)chroman and 7-hydroxy-3-(4-hydroxyphenyl)thiochroman derivatives with…”
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Newly discovered orally active pure antiestrogens by Kanbe, Yoshitake, Kim, Myung-Hwa, Nishimoto, Masahiro, Ohtake, Yoshihito, Yoneya, Takaaki, Ohizumi, Iwao, Tsunenari, Toshiaki, Taniguchi, Kenji, Kaiho, Shin-ichi, Nabuchi, Yoshiaki, Araya, Hiroshi, Kawata, Setsu, Morikawa, Kazumi, Jo, Jae-Chon, Kwon, Hee-An, Lim, Hyun-Suk, Kim, Hak-Yeop

“…Steroid derivatives bearing the carboxy moiety in the long side chain at the 7-α position exhibited remarkable antiestrogen activities when administered…”
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Identification of a novel, orally bioavailable estrogen receptor downregulator by Yoneya, Takaaki, Taniguchi, Kenji, Tsunenari, Toshiaki, Saito, Hidemi, Kanbe, Yoshitake, Morikawa, Kazumi, Yamada-Okabe, Hisafumi

“…Tamoxifen has been widely used for the treatment of estrogen receptor (ER)-positive breast cancer, but its partial agonist activity is considered to limit the…”
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Convenient method for the synthesis of C-alkylated purine nucleosides: palladium-catalyzed cross-coupling reaction of halogenopurine nucleosides with trialkylaluminums by Hirota, Kosaku, Kitade, Yukio, Kanbe, Yoshitake, Maki, Yoshifumi

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