Search Results - "KANAIZUMI, Etsuko"

Expression and localization of GPR99 in human nasal mucosa by Shirasaki, Hideaki, Kanaizumi, Etsuko, Himi, Tetsuo

“…Abstract Objective The cysteinyl leukotrienes (CysLTs) are lipid mediators that have been implicated in the pathogenesis of allergic rhinitis. Pharmacological…”
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Leukotriene E4 induces MUC5AC release from human airway epithelial NCI-H292 cells by Shirasaki, Hideaki, Kanaizumi, Etsuko, Seki, Nobuhiko, Himi, Tetsuo

“…Hypersecretion of mucin in the airway epithelium is an important feature of allergic airway diseases. Of the 3 cysteinyl leukotrienes (CysLTs; LTC4 LTD4 and…”
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Immunohistochemical localization of alpha and beta adrenergic receptors in the human nasal turbinate by Shirasaki, Hideaki, Kanaizumi, Etsuko, Himi, Tetsuo

“…Abstract Objective Adrenergic receptors (ARs) include four general types (α1, α2, β1 and β2), which are found in different target tissues. α-AR agonists are…”
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Localization and Up-Regulation of Cysteinyl Leukotriene-2 Receptor in Human Allergic Nasal Mucosa by Shirasaki, Hideaki, Kanaizumi, Etsuko, Seki, Nobuhiko, Fujita, Manabu, Kikuchi, Megumi, Himi, Tetsuo

“…Cysteinyl leukotrienes (CysLTs) are lipid mediators that have been implicated in the pathogenesis of allergic rhinitis. Pharmacological studies using CysLTs…”
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Localization and Upregulation of the Nasal Histamine H1 Receptor in Perennial Allergic Rhinitis by Himi, Tetsuo, Seki, Nobuhiko, Kanaizumi, Etsuko, Shirasaki, Hideaki

“…In the present study, we have investigated the expression of histamine H1 receptor in human turbinates by RT-PCR, western blotting, and immunohistochemistry…”
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Clinical benefit of component-resolved diagnosis in Japanese birch-allergic patients with a convincing history of apple or peach allergy by Shirasaki, Hideaki, Yamamoto, Tetsuo, Abe, Shu, Kanaizumi, Etsuko, Kikuchi, Megumi, Himi, Tetsuo

“…Abstract Objective In northern Japan, birch pollen is the major allergen in pollinosis, while oral allergy syndrome (OAS) is caused primarily by apple and…”
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Leukotriene D4 induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation by Shirasaki, Hideaki, Kanaizumi, Etsuko, Himi, Tetsuo

“…Numerous reports have shown that cysteinyl leukotrienes (CysLTs) contribute to tissue accumulation of eosinophils in allergic airway inflammation. To date,…”
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Expression and Localization of Purinergic P2Y12 Receptor in Human Nasal Mucosa by Shirasaki, Hideaki, Kanaizumi, Etsuko, Seki, Nobuhiko, Kikuchi, Megumi, Himi, Tetsuo

“…Extracellular nucleotides such as ATP and UTP are released from essentially all cells, and they interact with cell surface P2 receptors to produce a broad…”
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Leukotriene D 4 induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation by Shirasaki, Hideaki, Kanaizumi, Etsuko, Himi, Tetsuo

“…Numerous reports have shown that cysteinyl leukotrienes (CysLTs) contribute to tissue accumulation of eosinophils in allergic airway inflammation. To date,…”
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Leukotriene E4 induces MUC5AC release from human airway epithelial NCI-H292 cells by Hideaki Shirasaki, Etsuko Kanaizumi, Nobuhiko Seki, Tetsuo Himi

“…[ABSTRACT] Background: Hypersecretion of mucin in the airway epithelium is an important feature of allergic airway diseases. Of the 3 cysteinyl leukotrienes…”
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Anti-Leukotriene Therapy may be Effective for the Treatment of Salivary Eosinophilic Inflammation by Shirasaki, Hideaki, Kanaizumi, Etsuko, Himi, Tetsuo

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Immunohistochemical Localization of the Bradykinin B1 and B2 Receptors in Human Nasal Mucosa by Shirasaki, Hideaki, Himi, Tetsuo, Kanaizumi, Etsuko

“…Bradykinin (BK) has been tobe thought a potent mediator involved in allergic rhinitis because BK was recovered from the nasal lavage fluid of allergic rhinitis…”
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Accumulation of CRTH2-positive leukocytes in human allergic nasal mucosa by Shirasaki, Hideaki, MD, PhD, Kikuchi, Megumi, MD, PhD, Kanaizumi, Etsuko, MD, PhD, Himi, Tetsuo, MD, PhD

“…Background Prostaglandin D2 (PGD2 ) has been thought to be a potent mediator involved in allergic rhinitis because PGD2 has been recovered from the nasal…”
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Agonist-and TH2 cytokine-induced up-regulation of cysteinyl leukotriene receptor messenger RNA in human monocytes by SHIRASAKI, Hideaki, SEKI, Nobuhiko, FUJITA, Manabu, KIKUCHI, Megumi, KANAIZUMI, Etsuko, WATANABE, Kazumasa, HIMI, Tetsuo

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Expression and localization of the thromboxane A2 receptor in human nasal mucosa by Shirasaki, Hideaki, Kikuchi, Megumi, Seki, Nobuhiko, Kanaizumi, Etsuko, Watanabe, Kazumasa, Himi, Tetsuo

“…Abstract Thromboxane A2 (TXA2) has been thought a potent mediator involved in allergic rhinitis, because TXA2 was recovered from the nasal lavage fluid of…”
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Correlation of Local FOXP3-Expressing T Cells and Th1-Th2 Balance in Perennial Allergic Nasal Mucosa by Himi, Tetsuo, Seki, Nobuhiko, Kanaizumi, Etsuko, Shirasaki, Hideaki

“…Regulatory T cells (Treg) play some important roles in allergic rhinitis. The most specific marker for Treg is FOXP3, a recently identified transcription…”
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Distribution of specific binding sites for cysteinyl leukotriene 1 receptor antagonist in human nasal mucosa by Shirasaki, Hideaki, Kanaizumi, Etsuko, Seki, Nobuhiko, Kikuchi, Megumi, Watanabe, Kazumasa, Konno, Nobuhiro, Himi, Tetsuo

“…Conclusion. The high density of [3H]-pranlukast binding sites on the local leukocytes in human nasal mucosa suggests that CysLT1 receptor antagonists may…”
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Expression and localization of platelet-activating factor receptor in human nasal mucosa by Shirasaki, Hideaki, Seki, Nobuhiko, Kikuchi, Megumi, Kanaizumi, Etsuko, Watanabe, Kazumasa, Konno, Nobuhiro, Himi, Tetsuo

“…Platelet-activating factor (PAF) has been thought to be a potent mediator of allergic rhinitis because PAF was recovered from the nasal lavage fluid of…”
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Expression of neurokinin a receptor mRNA in human nasal mucosa by Shirasaki, Hideaki, Kanaizumi, Etsuko, Watanabe, Kazumasa, Konno, Nobuhiro, Sato, Jun, Asakura, Kohji, Kataura, Akikatsu, Himi, Tetsuo

“…In airway tissues, it has been suggested that tachykinins act as the transmitter for afferent sensory nerves which respond to various irritants and may be…”
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Effect of Cysteinyl Leukotriene Receptor Antagonists on Leukotirene D4-Induced Chemotaxis of Human Eosinophilc Cell Line, Eol-1 Cells by Shirasaki, Hideaki, MD, PhD, Kanaizumi, Etsuko, Fujita, Manabu, Sekioka, Tomohiko, Himi, Tetsuo

“…Rationale Many reports have shown that cysteinyl leukotrienes (CysLTs) contribute to tissue accumulation of eosinophils in allergic airway inflammation,…”
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