Search Results - "KANA, Bavesh D"

Energy Metabolism and Drug Efflux in Mycobacterium tuberculosis by BLACK, Philippa A, WARREN, Robin M, LOUW, Gail E, VAN HELDEN, Paul D, VICTOR, Thomas C, KANA, Bavesh D

“…The inherent drug susceptibility of microorganisms is determined by multiple factors, including growth state, the rate of drug diffusion into and out of the…”
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Cell Surface Biosynthesis and Remodeling Pathways in Mycobacteria Reveal New Drug Targets by Shaku, Moagi, Ealand, Christopher, Kana, Bavesh D

“…( ), the causative agent of tuberculosis (TB), remains the leading cause of death from an infectious bacterium and is responsible for 1.8 million deaths…”
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Detection of differentially culturable tubercle bacteria in sputum using mycobacterial culture filtrates by Gordhan, Bhavna G., Peters, Julian S., McIvor, Amanda, Machowski, Edith E., Ealand, Christopher, Waja, Ziyaad, Martinson, Neil, Kana, Bavesh D.

“…Rapid detection of tuberculosis (TB) infection is paramount to curb further transmission. The gold standard for this remains mycobacterial culture, however…”
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Mycobacterium smegmatis does not display functional redundancy in nitrate reductase enzymes by Cardoso, Nicole C, Papadopoulos, Andrea O, Kana, Bavesh D

“…Reduction of nitrate to nitrite in bacteria is an essential step in the nitrogen cycle, catalysed by a variety of nitrate reductase (NR) enzymes. The soil…”
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Survival and detection of SARS-CoV-2 variants on dry swabs post storage by Gordhan, Bhavna G, Ealand, Christopher S, Kana, Bavesh D

“…COVID-19 has resulted in nearly 598 million infections and over 6.46 million deaths since the start of the severe acute respiratory syndrome coronavirus 2…”
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A modified BCG with depletion of enzymes associated with peptidoglycan amidation induces enhanced protection against tuberculosis in mice by Shaku, Moagi Tube, Um, Peter K, Ocius, Karl L, Apostolos, Alexis J, Pires, Marcos M, Bishai, William R, Kana, Bavesh D

“…Mechanisms by which (Mtb) evades pathogen recognition receptor activation during infection may offer insights for the development of improved tuberculosis (TB)…”
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Functional Characterization of a Vitamin B12-Dependent Methylmalonyl Pathway in Mycobacterium tuberculosis: Implications for Propionate Metabolism during Growth on Fatty Acids by SAVVI, Suzana, WARNER, Digby F, KANA, Bavesh D, MCKINNEY, John D, MIZRAHI, Valerie, DAWES, Stephanie S

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Development of primer-probe sets to rapidly distinguish single nucleotide polymorphisms in SARS-CoV-2 lineages by Ealand, Christopher S, Gordhan, Bhavna G, Machowski, Edith E, Kana, Bavesh D

“…Ongoing SARS-CoV-2 infections are driven by the emergence of various variants, with differential propensities to escape immune containment. Single nucleotide…”
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The resuscitation‐promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro by Kana, Bavesh D., Gordhan, Bhavna G., Downing, Katrina J., Sung, Nackmoon, Vostroktunova, Galina, Machowski, Edith E., Tsenova, Liana, Young, Michael, Kaprelyants, Arseny, Kaplan, Gilla, Mizrahi, Valerie

“…Summary Mycobacterium tuberculosis contains five resuscitation‐promoting factor (Rpf)‐like proteins, RpfA‐E, that are implicated in resuscitation of this…”
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Amidation of glutamate residues in mycobacterial peptidoglycan is essential for cell wall cross-linking by Shaku, Moagi T., Ocius, Karl L., Apostolos, Alexis J., Pires, Marcos M., VanNieuwenhze, Michael S., Dhar, Neeraj, Kana, Bavesh D.

“…Mycobacteria assemble a complex cell wall with cross-linked peptidoglycan (PG) which plays an essential role in maintenance of cell wall integrity and…”
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Essential roles for imuA' - and imuB -encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis by Warner, Digby F., Ndwandwe, Duduzile E., Abrahams, Garth L., Kana, Bavesh D., Machowski, Edith E., Venclovas, Česlovas, Mizrahi, Valerie, Benkovic, Stephen J.

“…In Mycobacterium tuberculosis (Mtb), damage-induced mutagenesis is dependent on the C-family DNA polymerase, DnaE2. Included with dnaE2 in the Mtb SOS regulon…”
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The performance of tongue swabs for detection of pulmonary tuberculosis by Ealand, Christopher S., Sewcharran, Astika, Peters, Julian S., Gordhan, Bhavna G., Kamariza, Mireille, Bertozzi, Carolyn R., Waja, Ziyaad, Martinson, Neil A., Kana, Bavesh D.

“…IntroductionOral and/or tongue swabs have demonstrated ability to detect Mycobacterium tuberculosis (Mtb) in adults with pulmonary tuberculosis (TB). Swabs…”
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Investigating Non-sterilizing Cure in TB Patients at the End of Successful Anti-TB Therapy by Beltran, Caroline G G, Heunis, Tiaan, Gallant, James, Venter, Rouxjeane, du Plessis, Nelita, Loxton, Andre G, Trost, Matthias, Winter, Jill, Malherbe, Stephanus T, Kana, Bavesh D, Walzl, Gerhard

“…(Mtb) is extremely recalcitrant to antimicrobial chemotherapy requiring 6 months to treat drug-sensitive tuberculosis (TB). Despite this, 4-10% of cured…”
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Detection of differentially culturable tubercle bacteria in sputum from drug-resistant tuberculosis patients by Gordhan, Bhavna G., Sewcharran, Astika, Letsoalo, Marothi, Chinappa, Thilgavathy, Yende-Zuma, Nonhlanhla, Padayatchi, Nesri, Naidoo, Kogieleum, Kana, Bavesh D.

“…Several studies described the presence of non-replicating, drug-tolerant differentially culturable tubercle bacteria (DCTB) in sputum from patients with active…”
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Changes in Energy Metabolism of Mycobacterium Tuberculosis in Mouse Lung and Under in vitro Conditions Affecting Aerobic Respiration by Shi, Lanbo, Charles D. Sohaskey, Bavesh D. Kana, Stephanie Dawes, North, Robert J., Mizrahi, Valerie, Maria L. Gennaro

“…Transcription profiling of genes encoding components of the respiratory chain and the ATP synthesizing apparatus of Mycobactehum tuberculosis was conducted in…”
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Functional Analysis of Molybdopterin Biosynthesis in Mycobacteria Identifies a Fused Molybdopterin Synthase in Mycobacterium tuberculosis by WILLIAMS, Monique J, KANA, Bavesh D, MIZRAHI, Valerie

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The effect of previous SARS-CoV-2 infection on systemic immune responses in individuals with tuberculosis by Xavier, Mariana S, Araujo-Pereira, Mariana, de Oliveira, Quezia M, Sant'Anna, Flavia M, Ridolfi, Felipe M, de Andrade, Alice M S, Figueiredo, Marina C, Sterling, Timothy R, Gordhan, Bhavna G, Kana, Bavesh D, Andrade, Bruno B, Rolla, Valeria C, Gomes-Silva, Adriano

“…The impact of previous SARS-CoV-2 infection on the systemic immune response during tuberculosis (TB) disease has not been explored. An observational,…”
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Culture filtrate supplementation can be used to improve Mycobacterium tuberculosis culture positivity for spinal tuberculosis diagnosis by Beltran, Caroline G G, Venter, Rouxjeane, Mann, Theresa N, Davis, Johan H, Kana, Bavesh D, Walzl, Gerhard

“…Culture remains the gold standard to diagnose spinal tuberculosis (STB) despite the paucibacillary nature of the disease. Current methods can take up to 42…”
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Differentially culturable tubercle bacteria as a measure of tuberculosis treatment response by Peters, Julian S, McIvor, Amanda, Papadopoulos, Andrea O, Masangana, Tshepiso, Gordhan, Bhavna G, Waja, Ziyaad, Otwombe, Kennedy, Letutu, Matebogo, Kamariza, Mireille, Sterling, Timothy R, Bertozzi, Carolyn R, Martinson, Neil A, Kana, Bavesh D

“…Routine efficacy assessments of new tuberculosis (TB) treatments include quantitative solid culture or routine liquid culture, which likely miss quantification…”
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Role of the DinB Homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis by KANA, Bavesh D, ABRAHAMS, Garth L, MIZRAHI, Valerie, SUNG, Nackmoon, WARNER, Digby F, GORDHAN, Bhavna G, MACHOWSKI, Edith E, TSENOVA, Liana, SACCHETTINI, James C, STOKER, Neil G, KAPLAN, Gilla

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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