Search Results - "KAMPINE, JOHN P"
-
1
Cholinergic reversal of isoflurane anesthesia in rats as measured by cross-approximate entropy of the electroencephalogram
Published in Anesthesiology (Philadelphia) (01-11-2003)“…Pharmacologic modulation of the state of consciousness is of interest for clinical practice and for a better understanding of anesthetic mechanisms. The…”
Get full text
Journal Article -
2
Reactive oxygen species precede the epsilon isoform of protein kinase C in the anesthetic preconditioning signaling cascade
Published in Anesthesiology (Philadelphia) (01-08-2003)“…Protein kinase C (PKC) and reactive oxygen species (ROS) are known to have a role in anesthetic preconditioning (APC). Cardiac preconditioning by triggers…”
Get full text
Journal Article -
3
Sevoflurane mimics ischemic Preconditioning effects on coronary flow and nitric oxide release in isolated hearts
Published in Anesthesiology (Philadelphia) (01-09-1999)“…Like ischemic preconditioning, certain volatile anesthetics have been shown to reduce the magnitude of ischemia/ reperfusion injury via activation of K+…”
Get full text
Journal Article -
4
Sevoflurane depresses glutamatergic neurotransmission to brainstem inspiratory premotor neurons but not postsynaptic receptor function in a decerebrate dog model
Published in Anesthesiology (Philadelphia) (01-07-2005)“…Inspiratory bulbospinal neurons in the caudal ventral medulla are premotor neurons that drive motoneurons, which innervate pump muscles such as the diaphragm…”
Get full text
Journal Article -
5
Sevoflurane enhances γ-aminobutyric acid type A receptor function and overall inhibition of inspiratory premotor neurons in a decerebrate dog model
Published in Anesthesiology (Philadelphia) (01-07-2005)“…Inspiratory premotor neurons in the caudal ventral medulla relay excitatory drive to phrenic and inspiratory intercostal motoneurons in the spinal cord. These…”
Get full text
Journal Article -
6
Isoflurane-induced cerebral hyperemia is partially mediated by nitric oxide and epoxyeicosatrienoic acids in mice in vivo
Published in Anesthesiology (Philadelphia) (01-12-2002)“…Despite intense investigation, the mechanism of isoflurane-induced cerebral hyperemia is unclear. The current study was designed to determine the contributions…”
Get full text
Journal Article -
7
Effects of Halothane and sevoflurane on inhibitory neurotransmission to medullary expiratory neurons in a decerebrate dog model
Published in Anesthesiology (Philadelphia) (01-04-2002)“…In canine expiratory bulbospinal neurons, 1 minimum alveolar concentration (MAC) halothane and sevoflurane reduced the glutamatergic excitatory drive at a…”
Get full text
Journal Article -
8
Dynorphinergic mechanism mediating endomorphin-2-induced antianalgesia in the mouse spinal cord
Published in The Journal of pharmacology and experimental therapeutics (01-12-2003)“…We have previously demonstrated that both endomorphin-1 (EM-1) and endomorphin-2 (EM-2) at high doses (1.75-35 nmol) given intrathecally (i.t.) or…”
Get more information
Journal Article -
9
Effect of hemodilution on RBC velocity, supply rate, and hematocrit in the cerebral capillary network
Published in Journal of applied physiology (1985) (01-08-1999)“…Departments of Anesthesiology and Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 The effect of isovolemic hemodilution on the circulation…”
Get full text
Journal Article -
10
Reversal of minimum alveolar concentrations of volatile anesthetics by chromosomal substitution
Published in Anesthesiology (Philadelphia) (01-09-2004)Get full text
Journal Article -
11
Effects of Sevoflurane on excitatory neurotransmission to medullary expiratory neurons and on phrenic nerve activity in a decerebrate dog model
Published in Anesthesiology (Philadelphia) (01-08-2001)“…Sevoflurane is a new volatile anesthetic with a pronounced respiratory depressant effect. Synaptic neurotransmission in canine expiratory bulbospinal neurons…”
Get full text
Journal Article -
12
Halothane depresses glutamatergic neurotransmission to brain stem inspiratory premotor neurons in a decerebrate dog model
Published in Anesthesiology (Philadelphia) (01-04-2003)“…Inspiratory bulbospinal neurons in the caudal ventral medulla are premotor neurons that drive phrenic motoneurons and ultimately the diaphragm. Excitatory…”
Get full text
Journal Article -
13
Halothane enhances γ-aminobutyric acid receptor type A function but does not change overall inhibition in Inspiratory premotor neurons in a decerebrate dog model
Published in Anesthesiology (Philadelphia) (01-12-2003)“…Inspiratory premotor neurons in the caudal ventral medulla relay excitatory drive to phrenic and inspiratory intercostal motoneurons in the spinal cord. These…”
Get full text
Journal Article -
14
Mechanisms of isoflurane-mediated hyperpolarization of Vascular smooth muscle in chronically hypertensive and normotensive conditions
Published in Anesthesiology (Philadelphia) (01-03-2001)“…The purpose of this study was to compare the effects of isoflurane on membrane and intracellular mechanisms that regulate vascular smooth muscle (VSM)…”
Get full text
Journal Article -
15
Effects of halothane on excitatory neurotransmission to medullary expiratory neurons in a decerebrate dog model
Published in Anesthesiology (Philadelphia) (01-12-2000)“…The activity of canine expiratory (E) neurons in the caudal ventral respiratory group is primarily dependent on N-methyl-D-aspartic acid (NMDA)…”
Get full text
Journal Article -
16
Effects of volatile anesthetic agents on in situ vascular smooth muscle transmembrane potential in resistance- and capacitance-regulating blood vessels
Published in Anesthesiology (Philadelphia) (01-04-1998)“…This study was designed to compare the inhibitory effect of inhaled volatile anesthetic agents on in situ sympathetic neural versus nonneural regulation of…”
Get full text
Journal Article -
17
In vivo effects of dexmedetomidine on laser-doppler flow and pial arteriolar diameter
Published in Anesthesiology (Philadelphia) (01-02-1998)“…The alpha2-adrenergic agonist dexmedetomidine alters global cerebral blood flow (CBF). However, few studies have investigated the action of dexmedetomidine on…”
Get full text
Journal Article -
18
Potassium channel-mediated hyperpolarization of mesenteric vascular smooth muscle by isoflurane
Published in Anesthesiology (Philadelphia) (01-03-1999)“…A primary source of calcium (Ca2+) necessary for excitation contraction in vascular smooth muscle (VSM) is influx via voltage-dependent Ca2+ channels. Thus,…”
Get full text
Journal Article -
19
Differential antinociceptive effects of endomorphin-1 and endomorphin-2 in the mouse
Published in The Journal of pharmacology and experimental therapeutics (01-02-2000)“…Two highly selective mu-opioid receptor agonists, endomorphin-1 and endomorphin-2, have been identified and postulated to be endogenous mu-opioid receptor…”
Get more information
Journal Article -
20
Nitric oxide synthase inhibitor augments post-ischemic leukocyte adhesion in the cerebral microcirculation in vivo
Published in Neurological research (New York) (01-06-1999)“…The objective was to examine the effect of the nitric oxide synthase inhibitor, N^-nitro-L-arginine methyl ester (L-NAME) on leukocyte adhesion in the cerebral…”
Get full text
Journal Article