Search Results - "KAMINSKI, W. E"
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Pulmonary embolism: CT signs and cardiac biomarkers for predicting right ventricular dysfunction
Published in The European respiratory journal (01-04-2012)“…The aim of this study was to prospectively evaluate the accuracy of quantitative cardiac computed tomography (CT) parameters and two cardiac biomarkers…”
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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
Published in Nature genetics (01-08-1999)“…Tangier disease (TD) is an autosomal recessive disorder of lipid metabolism. It is characterized by absence of plasma high-density lipoprotein (HDL) and…”
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Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1 -deficient mice
Published in Nature genetics (01-02-2000)“…Mutations in the gene encoding ATP-binding cassette transporter 1 ( ABC1) have been reported in Tangier disease (TD), an autosomal recessive disorder that is…”
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ABCA2: a candidate regulator of neural transmembrane lipid transport
Published in Cellular and molecular life sciences : CMLS (01-08-2002)“…Studies in the past years have implicated multispan transmembrane transport molecules of the ATP binding cassette (ABC) transporter family in cellular lipid…”
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5
Elastosis perforans serpiginosa‐like pseudoxanthoma elasticum in a child with severe Moya Moya disease
Published in British journal of dermatology (1951) (01-08-2005)“…Summary A 2‐year‐old girl with Moya Moya disease who had relapsing cerebrovascular strokes presented with loose skin folds, ‘chicken’ skin appearance and…”
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A comparison of the diagnostic utility of the sFlt-1/PlGF ratio versus PlGF alone for the detection of preeclampsia/HELLP syndrome
Published in Hypertension in pregnancy (01-08-2016)“…Objective: The Elecsys ® immunoassay sFlt-1/PlGF ratio and the Triage ® PlGF assay were compared (in a prospective, multicenter, case-control study) for…”
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Detection of in vivo hepatitis B virus surface antigen mutations—A comparison of four routine screening assays
Published in Journal of viral hepatitis (01-10-2018)“…Summary An important requirement for a state‐of‐the‐art hepatitis B surface antigen (HBsAg) screening assay is reliable detection of mutated HBsAg. Currently,…”
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Identification of novel mutations in the NPC1 gene in German patients with Niemann–Pick C disease
Published in Journal of inherited metabolic disease (01-09-2002)“…Niemann–Pick disease type C (NPC) is an inherited neuro degenerative disorder associated with intracellular cholesterol trafficking defects. Mutations in two…”
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Thrombosis and inflammation as multicellular processes: significance of cell-cell interactions
Published in Thrombosis and haemostasis (01-07-1995)“…Platelet activation as a result of vascular injury provokes endothelial cells to respond in a manner which limits or reverses the occlusive consequences of…”
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Dietary ω-3 Fatty Acids Lower Levels of Platelet-Derived Growth Factor mRNA in Human Mononuclear Cells
Published in Blood (01-04-1993)“…Platelet-derived growth factor (PDGF) is a potent mitogen thought to propagate atherosclerosis and other proliferative or inflammatory diseases. Some of these…”
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Endothelial Cells of Hematopoietic Origin Make a Significant Contribution to Adult Blood Vessel Formation
Published in Circulation research (27-10-2000)“…Granulation tissue formation is an example of new tissue development in an adult. Its rich vascular network has been thought to derive via angiogenic sprouting…”
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Leukocyte ABCA1 Controls Susceptibility to Atherosclerosis and Macrophage Recruitment into Tissues
Published in Proceedings of the National Academy of Sciences - PNAS (30-04-2002)“…The ATP-binding cassette transporter 1 (ABCA1) has recently been identified as a key regulator of high-density lipoprotein (HDL) metabolism, which is defective…”
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ABCG1 (ABC8), the Human Homolog of the Drosophila white Gene, Is a Regulator of Macrophage Cholesterol and Phospholipid Transport
Published in Proceedings of the National Academy of Sciences - PNAS (18-01-2000)“…Excessive uptake of atherogenic lipoproteins such as modified low-density lipoprotein complexes by vascular macrophages leads to foam cell formation, a…”
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Molecular Cloning of the Human ATP-Binding Cassette Transporter 1 (hABC1): Evidence for Sterol-Dependent Regulation in Macrophages
Published in Biochemical and biophysical research communications (02-04-1999)“…We have cloned the full-length cDNA for the human ATP binding cassette transporter 1 (hABC1). The 6603-bp open reading frame encodes a polypeptide of 2201…”
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ATP-binding cassette transporter A1 (ABCA1) in macrophages: a dual function in inflammation and lipid metabolism?
Published in Pathobiology (Basel) (01-01-1999)“…Activated lipid-laden macrophages in the vascular wall are key modulators of the inflammatory processes underlying atherosclerosis. We demonstrate here that…”
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Isolation of human promoter regions by Alu repeat consensus-based polymerase chain reaction
Published in Genomics (San Diego, Calif.) (15-05-1998)“…Knowledge of the promoter structure is critical for an understanding of the regulation of genes. We demonstrate by analysis of 405 human genes that human…”
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ABC transporters in cellular lipid trafficking
Published in Current opinion in lipidology (01-10-2000)“…ATP-binding cassette (ABC) transporters constitute a group of evolutionary highly conserved cellular transmembrane transport proteins. Recent work has…”
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Identification of a Novel Human Sterol-Sensitive ATP-Binding Cassette Transporter (ABCA7)
Published in Biochemical and biophysical research communications (05-07-2000)“…We report the identification of the full-length cDNA for a novel ATP-binding cassette (ABC) transporter from human macrophages. The mRNA is of 6.8 kb size and…”
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ABCA6, a Novel A Subclass ABC Transporter
Published in Biochemical and biophysical research communications (03-08-2001)“…Here we report the cDNA cloning of a novel member of the ABC A transporter subfamily from human macrophages. The identified coding sequence is of 5.0 kb size…”
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Human mononuclear cells express 12-LX : coordinated mRNA regulation with 5-LX and FLAP genes
Published in Blood (1996)“…Lipoxygenases (LXs) catalyze formation of leukotrienes and hydroxy-eicosatetraenoic acids (HETEs), proinflammatory, and spasmogenic autacoids that are critical…”
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