Search Results - "KAMESHIMA, Hidekazu"

An Optimal Timing for Removing a Drain After Breast Surgery: A Systematic Review and Meta-Analysis by Shima, Hiroaki, Kutomi, Goro, Sato, Kiminori, Kuga, Yoko, Wada, Asaka, Satomi, Fukino, Uno, Satoko, Nisikawa, Noriko, Kameshima, Hidekazu, Ohmura, Tosei, Mizuguchi, Toru, Takemasa, Ichiro

“…In clinical practice, drains had been routinely used for reducing seroma formation after breast surgery. However, an optimal timing to remove drains does not…”
Get full text

Immunogenic enhancement and clinical effect by type‐I interferon of anti‐apoptotic protein, survivin‐derived peptide vaccine, in advanced colorectal cancer patients by Kameshima, Hidekazu, Tsuruma, Tetsuhiro, Torigoe, Toshihiko, Takahashi, Akari, Hirohashi, Yoshihiko, Tamura, Yasuaki, Tsukahara, Tomohide, Ichimiya, Shingo, Kanaseki, Takayuki, Iwayama, Yuji, Sato, Noriyuki, Hirata, Koichi

“…We previously identified a human leukocyte antigen (HLA)‐A24‐restricted antigenic peptide, survivin‐2B80‐88, recognized by CD8+ cytotoxic T lymphocytes (CTL)…”
Get full text

Immunotherapeutic benefit of α‐interferon (IFNα) in survivin2B‐derived peptide vaccination for advanced pancreatic cancer patients by Kameshima, Hidekazu, Tsuruma, Tetsuhiro, Kutomi, Goro, Shima, Hiroaki, Iwayama, Yuji, Kimura, Yasutoshi, Imamura, Masahumi, Torigoe, Toshihiko, Takahashi, Akari, Hirohashi, Yoshihiko, Tamura, Yasuaki, Tsukahara, Tomohide, Kanaseki, Takayuki, Sato, Noriyuki, Hirata, Koichi

“…Survivin, a member of the inhibitor of apoptosis protein (IAP) family containing a single baculovirus IAP repeat domain, is highly expressed in cancerous…”
Get full text

Development of a T‐cell receptor multimer with high avidity for detecting a naturally presented tumor‐associated antigen on osteosarcoma cells by Watanabe, Kazue, Tsukahara, Tomohide, Toji, Shingo, Saitoh, Shogo, Hirohashi, Yoshihiko, Nakatsugawa, Munehide, Kubo, Terufumi, Kanaseki, Takayuki, Kameshima, Hidekazu, Terui, Takeshi, Sato, Noriyuki, Torigoe, Toshihiko

“…For efficacy of peptide vaccination immunotherapy for patients with cancer, endogenous expression of the target peptide/human leukocyte antigen (HLA) on cancer…”
Get full text

Peptide vaccinations elicited strong immune responses that were reboosted by anti-PD1 therapy in a patient with myxofibrosarcoma by Tsukahara, Tomohide, Watanabe, Kazue, Murata, Kenji, Takahashi, Akari, Mizushima, Emi, Shibayama, Yuji, Kameshima, Hidekazu, Hatae, Ryo, Ohno, Yasuo, Kawahara, Rituko, Murai, Aiko, Nakatsugawa, Munehide, Kubo, Terufumi, Kanaseki, Takayuki, Hirohashi, Yoshihiko, Terui, Takeshi, Asanuma, Hiroko, Hasegawa, Tadashi, Sato, Noriyuki, Torigoe, Toshihiko

“…Peptide-based immunotherapy does not usually elicit strong immunological and clinical responses in patients with end-stage cancer, including sarcoma. Here we…”
Get full text

A phase I study of combination therapy with nanoparticle albumin-bound paclitaxel and cyclophosphamide in patients with metastatic or recurrent breast cancer by Kutomi, Goro, Ohmura, Tousei, Satomi, Fukino, Maeda, Hideki, Shima, Hiroaki, Kameshima, Hidekazu, Okazaki, Minoru, Masuoka, Hideji, Sasaki, Kenichi, Hirata, Koichi

“…Background The objective of the present clinical study is to determine the maximum tolerated dose (MTD)/recommended dose (RD) of combination therapy with…”
Get full text

Evaluating the utility of N1,N12-diacetylspermine and N1,N8-diacetylspermidine in urine as tumor markers for breast and colorectal cancers by Umemori, Yoshifumi, Ohe, Yui, Kuribayashi, Kageaki, Tsuji, Naoki, Nishidate, Toshihiko, Kameshima, Hidekazu, Hirata, Koichi, Watanabe, Naoki

“…Among natural polyamines, the concentrations of the diacetylated form of spermine and spermidine increase in the urine of patients with cancer. We evaluated…”
Get full text

Quantitative reverse transcription-PCR assay of the RNA component of human telomerase using the TaqMan fluorogenic detection system by Yajima, Tomomi, Yagihashi, Atsuhito, Kameshima, Hidekazu, Kobayashi, Daisuke, Furuya, Daisuke, Hirata, Koichi, Watanabe, Naoki

“…We established the validity of a quantitative reverse transcription (RT)-PCR assay for the RNA component of human telomerase (hTR), using the TaqMan…”
Get full text

Helicobacter pylori Infection: Augmentation of Telomerase Activity in Cancer and Noncancerous Tissues by Kameshima, Hidekazu, Yagihashi, Atsuhito, Yajima, Tomomi, Kobayashi, Daisuke, Denno, Ryuichi, Hirata, Koichi, Watanabe, Naoki

“… Telomerase adds hexameric repeats of 5′‐TTAGGG‐3′ to the ends of chromosomal DNA (telomere) and has been implicated in cell immortalization and cellular…”
Get full text

Role of Human Telomerase Reverse Transcriptase and Telomeric‐repeat Binding Factor Proteins 1 and 2 in Human Hematopoietic Cells by Yamada, Koji, Yajima, Tomomi, Yagihashi, Atsuhito, Kobayashi, Daisuke, Koyanagi, Yoko, Asanuma, Koichi, Yamada, Mikako, Moriai, Ryosuke, Kameshima, Hidekazu, Watanabe, Naoki

“…Telomerase, an enzyme that adds hexameric repeats of 5′‐TTAGGG‐3′, termed telomeres, to the ends of chromosomal DNA, has been implicated in cellular…”
Get full text

Additional effect of anthracycline in preoperative chemotherapy with a sequential anthracycline‑containing regimen preceded by pertuzumab, trastuzumab and docetaxel combination therapy by Shima, Hiroaki, Kutomi, Goro, Kuga, Yoko, Wada, Asaka, Satomi, Fukino, Sato, Kiminori, Kyuno, Daisuke, Nishikawa, Noriko, Uno, Satoko, Kameshima, Hidekazu, Ohmura, Tosei, Hasegawa, Tadashi, Takemasa, Ichiro

“…The proper use of anthracycline-containing regimens in combination with anti-HER2-targeted therapy in a neoadjuvant setting for patients with HER2-positive…”
Get full text

Evaluating the utility of N 1, N 12-diacetylspermine and N 1, N 8-diacetylspermidine in urine as tumor markers for breast and colorectal cancers by Umemori, Yoshifumi, Ohe, Yui, Kuribayashi, Kageaki, Tsuji, Naoki, Nishidate, Toshihiko, Kameshima, Hidekazu, Hirata, Koichi, Watanabe, Naoki

“…Among natural polyamines, the concentrations of the diacetylated form of spermine and spermidine increase in the urine of patients with cancer. We evaluated…”
Get full text

Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine by Shima, Hiroaki, Kutomi, Goro, Satomi, Fukino, Imamura, Masafumi, Kimura, Yasutoshi, Mizuguchi, Toru, Watanabe, Kazue, Takahashi, Akari, Murai, Aiko, Tsukahara, Tomohide, Kanaseki, Takayuki, Hirohashi, Yoshihiko, Iwayama, Yuji, Tsuruma, Tetsuhiro, Kameshima, Hidekazu, Sato, Noriyuki, Torigoe, Toshihiko, Takemasa, Ichiro

“…A 62-year-old woman who underwent surgery to treat pancreatic cancer provided written, informed consent to undergo adjuvant therapy with gemcitabine, tegafur,…”
Get full text

Heat-shock protein-73 protects against small intestinal warm ischemiareperfusion injury in the rat by Tsuruma, Tetsuhiro, Yagihashi, Atsuhito, Watanabe, Naoki, Yajima, Tomomi, Kameshima, Hidekazu, Araya, Jun, Hirata, Koichi

“…Background: The protective effects of heat-shock protein (hsp) in rat small intestinal warm ischemia-reperfusion (I/R) injury are poorly understood. Methods:…”
Get full text

Positional advantages of supine MRI for diagnosis prior to breast‑conserving surgery by Kutomi, Goro, Shima, Hiroaki, Kyuno, Daisuke, Satomi, Fukino, Wada, Asaka, Kuga, Yoko, Okazaki, Minoru, Okazaki, Akira, Masuoka, Hideji, Mikami, Toshihiko, Yuyama, Yuichi, Matsuno, Takashi, Ohmura, Tosei, Kameshima, Hidekazu, Mizuguchi, Toru, Takemasa, Ichiro

“…The present study aimed to evaluate the rate of positive surgical margins for magnetic resonance imaging (MRI) performed in the supine position prior to…”
Get full text

Pigmented mammary Paget's disease mimicking melanoma: report of three cases by HIDA, Tokimasa, YONETA, Akihiro, NISHIZAKA, Takahiro, OHMURA, Tousei, SUZUKI, Yasuyo, KAMESHIMA, Hidekazu, YAMASHITA, Toshiharu

“…Pigmented mammary Paget's disease (PMPD) is a rare subtype of mammary Paget's disease. The differential diagnosis of PMPD and melanoma is difficult clinically…”
Get full text

Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes by Takahashi, Akari, Torigoe, Toshihiko, Tamura, Yasuaki, Kanaseki, Takayuki, Tsukahara, Tomohide, Sasaki, Yasushi, Kameshima, Hidekazu, Tsuruma, Tetsuhiro, Hirata, Koichi, Tokino, Takashi, Hirohashi, Yoshihiko, Sato, Noriyuki

“…Focal inflammation causes systemic fever. Cancer hyperthermia therapy results in shrinkage of tumors by various mechanisms, including induction of adaptive…”
Get full text

Risk of node metastasis of sentinel lymph nodes detected in level II/III of the axilla by single-photon emission computed tomography/computed tomography by SHIMA, HIROAKI, KUTOMI, GORO, SATOMI, FUKINO, MAEDA, HIDEKI, TAKAMARU, TOMOKO, KAMESHIMA, HIDEKAZU, OMURA, TOSEI, MORI, MITSURU, HATAKENAKA, MASAMITSU, HASEGAWA, TADASHI, HIRATA, KOICHI

“…In breast cancer, single-photon emission computed tomography/computed tomography (SPECT/CT) shows the exact anatomical location of sentinel nodes (SN)…”
Get full text

Immunotherapeutic benefit of α‐interferon (IFNα) in survivin2 B ‐derived peptide vaccination for advanced pancreatic cancer patients by Kameshima, Hidekazu, Tsuruma, Tetsuhiro, Kutomi, Goro, Shima, Hiroaki, Iwayama, Yuji, Kimura, Yasutoshi, Imamura, Masahumi, Torigoe, Toshihiko, Takahashi, Akari, Hirohashi, Yoshihiko, Tamura, Yasuaki, Tsukahara, Tomohide, Kanaseki, Takayuki, Sato, Noriyuki, Hirata, Koichi

“…Survivin, a member of the inhibitor of apoptosis protein ( IAP ) family containing a single baculovirus IAP repeat domain, is highly expressed in cancerous…”
Get full text

Use of the dye-guided sentinel lymph node biopsy method alone for breast cancer metastasis to avoid unnecessary axillary lymph node dissection by TAKAMARU, TOMOKO, KUTOMI, GORO, SATOMI, FUKINO, SHIMA, HIROAKI, OHNO, KEISUKE, KAMESHIMA, HIDEKAZU, SUZUKI, YASUYO, OHMURA, TOUSEI, TAKAMARU, HIROYUKI, NOJIMA, MASANORI, MORI, MITSURU, HIRATA, KOICHI

“…For sentinel lymph node biopsy (SLNB), a combination of dye-guided and γ-probe-guided methods is the most commonly used technique. However, the number of…”
Get full text