Search Results - "KAMANO, Yoshiaki"

QSAR Evaluation of the Ch'an Su and Related Bufadienolides against the Colchicine-Resistant Primary Liver Carcinoma Cell Line PLC/PRF/5 by Kamano, Yoshiaki, Yamashita, Ayano, Nogawa, Toshihiko, Morita, Hiroshi, Takeya, Koichi, Itokawa, Hideji, Segawa, Toshiaki, Yukita, Ayako, Saito, Kyoko, Katsuyama, Mariko, Pettit, George R

“…QSAR analysis has been used to identify the essential structural requirements for increasing the inhibitory activities of selected bufadienolides from the…”
Get full text

Isolation and Structure of Five New Cancer Cell Growth Inhibitory Bufadienolides from the Chinese Traditional Drug Ch'an Su by Nogawa, Toshihiko, Kamano, Yoshiaki, Yamashita, Ayano, Pettit, George R

“…Five new bufadienolides, 3β-formyloxyresibufogenin (1), 19-oxobufalin (2), 19-oxodesacetylcinobufagin (3), 6α-hydroxycinobufagin (4), and 1β-hydroxybufalin…”
Get full text

Isolation and Structure of a 20,21-Epoxybufenolide Series from “Ch'an Su” by Kamano, Yoshiaki, Nogawa, Toshihiko, Yamashita, Ayano, Hayashi, Masahiko, Inoue, Masuo, Drašar, Pavel, Pettit, George R

“…Steroid bufenolides resulting from epoxidation of the 17β-2-pyrone ring of bufadienolides are rare. Five 20,21-epoxybufenolides, namely,…”
Get full text

Structure-cytotoxic activity relationship for the toad poison bufadienolides by Kamano, Y, Kotake, A, Hashima, H, Inoue, M, Morita, H, Takeya, K, Itokawa, H, Nandachi, N, Segawa, T, Yukita, A, Saitou, K, Katsuyama, M, Pettit, G R

“…The toad poison bufadienolides including natural and derivatized compounds were tested for their cytotoxic effects on primary liver carcinoma cells PLC/PRF/5…”
Get full text

Biological activity of a novel nonpeptide antagonist to the interleukin-6 receptor 20S,21-epoxy-resibufogenin-3-formate by Hayashi, Masahiko, Rho, Mun-Chual, Fukami, Akiko, Enomoto, Akiko, Nonaka, Shinobu, Sekiguchi, Yoshino, Yanagisawa, Tadashi, Yamashita, Ayano, Nogawa, Toshihiko, Kamano, Yoshiaki, Komiyama, Kanki

“…Interleukin (IL)-6 is a key mediator in the regulation and coordination of the immune response and participates in pathogenesis of cancer cachexia, autoimmune…”
Get more information

Isolation and structure of convolutamydines B ∼ D from marine bryozoan Amathia convoluta by Zhang, Hui-ping, Kamano, Yoshiaki, Ichihara, Yoshitatsu, Kizu, Haruhisa, Komiyama, Kanki, Itokawa, Hideji, Pettit, George R

“…Convolutamydines B ∼ D (2 ∼ 4), three new alkaloids containing a dibromohydroxyoxindole moiety, were isolated from the Floridian bryozoan Amathia convoluta and…”
Get full text

The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10 by Pettit, George R, Kamano, Yoshiaki, Herald, Cherry L, Tuinman, Albert A, Boettner, Fred E, Kizu, Haruhisa, Schmidt, Jean M, Baczynskyj, Lubomir, Tomer, Kenneth B, Bontems, Roger J

Get full text

Synthesis and biological activities of the marine bryozoan alkaloids convolutamines A, C and F, and lutamides A and C by HASHIMA, H, HAYASHI, M, KAMANO, Y, SATO, N

“…Synthesis of convolutamines and lutamides, new 2,4,6-tribromo-3-methoxyphenethylamine alkaloids isolated from Floridian marine bryozoan Amathia convoluta, was…”
Get full text

Isolation and structure of the cytostatic linear depsipeptide dolastatin 15 by Pettit, George R, Kamano, Yoshiaki, Dufresne, Claude, Cerny, Ronald L, Herald, Cherry L, Schmidt, Jean M

“…The Indian Ocean sea hare Dolabella auricularia has been found to contain a strongly cytostatic depsipeptide constituent designated dolastatin 15. The unusual…”
Get full text

Isolation and Crystal Structure of Stylopeptide 1, A New Marine Porifera Cycloheptapeptide by Pettit, George R, Srirangam, Jayaram K, Herald, Delbert L, Xu, Jun-ping, Boyd, Michael R, Cichacz, Zbigniew, Kamano, Yoshiaki, Schmidt, Jean M, Erickson, Karen L

Get full text

Antineoplastic Agents. 340. Isolation and Structural Elucidation of Bryostatins 16−18 by Pettit, George R, Gao, Feng, Blumberg, Peter M, Herald, Cherry L, Coll, John C, Kamano, Yoshiaki, Lewin, Nancy E, Schmidt, Jean M, Chapuis, Jean-Charles

“…Separation of two trace cancer cell growth inhibitory (P388 leukemia) fractions from about 1000 kg of wet Gulf of Mexico Bugula neritina (Bryozoa) has led to…”
Get full text

Conformational analysis of a marine antineoplastic macrolide, bryostatin 10 by Kamano, Yoshiaki, Zhang, Hui-ping, Morita, Hiroshi, Itokawa, Hideji, Shirota, Osamu, Pettit, George R., Herald, Delbert L., Herald, Cherry L.

“…Conformation of bryostatin 10, a marine antineoplastic macrolide, in CDCl 3 was analyzed by the spectroscopic and computational chemical methods. A combination…”
Get full text

Bufobutanoic Acid and Bufopyramide, Two New Indole Alkaloids from the Chinese Traditional Drug Ch'an Su by Kamano, Yoshiaki, Morita, Hiroshi, Takano, Rui, Kotake, Ayano, Nogawa, Toshihiko, Hashima, Hirohumi, Takeya, Koichi, Itokawa, Hideji, R. Pettit, George

Get full text

Antineoplastic agent. 174. Isolation and structure of the cytostatic depsipeptide dolastatin 13 from the sea hare Dolabella auricularia by Pettit, George R, Kamano, Yoshiaki, Herald, Cherry L, Dufresne, Claude, Cerny, Ronald L, Herald, Delbert L, Schmidt, Jean M, Kizu, Haruhisa

Get full text

An Improved Source of Bryostatin 10, Bugula neritina from the Gulf of Aomori, Japan by Kamano, Yoshiaki, Zhang, Hui-Ping, Hino, Akiya, Yoshida, Motoyuki, Pettit, George R, Herald, Cherry L, Itokawa, Hideji

“…Bryostatins have been isolated from diverse Japanese coastal specimens of Bugula neritina guided by inhibitory activity against fertilized sea urchin egg cell…”
Get full text

Antineoplastic agents. 190. Isolation and structure of the cyclodepsipeptide dolastatin 14 by Pettit, George R, Kamano, Yoshiaki, Herald, Cherry L, Dufresne, Claude, Bates, Robert B, Schmidt, Jean M, Cerny, Ronald L, Kizu, Haruhisa

Get full text

Structure of bryostatin. 4. An important antineoplastic constituent of geographically diverse Bugula neritina (Bryozoa) by Pettit, George R, Kamano, Yoshiaki, Herald, Cherry L, Tozawa, Machiko

Get full text

Isolation and structure of the cell growth inhibitory depsipeptides dolastatins 11 and 12 by PETTIT, G. R, KAMANO, Y, KIZU, H, DUFRESNE, C, HERALD, C. L, BONTEMS, R. J, SCHMIDT, J. M, BOETTNER, F. E, NIEMAN, R. A

Get full text

Antineoplastic agents. 150. The structure and synthesis of dolastatin 3 by Pettit, George R, Kamano, Yoshiaki, Holzapfel, Cedric W, Van Zyl, Wynand J, Tuinman, Albert A, Herald, Cherry L, Baczynskyj, Lubomir, Schmidt, Jean M

Get full text

Qsar evaluation of the Ch'an Su and related bufadienolides against the colchicine-resistant primary liver carcinoma cell line PLC/PRF/51 by KAMANO, Yoshiaki, YAMASHITA, Ayano, PETTIT, George R, NOGAWA, Toshihiko, MORITA, Hiroshi, TAKEYA, Koichi, ITOKAWA, Hideji, SEGAWA, Toshiaki, YUKITA, Ayako, SAITO, Kyoko, KATSUYAMA, Mariko

Get full text