Quantitative Evaluation of Exercise Tl-201 Myocardial Scintigraphy Before and After Transluminal Coronary Angioplasty A Preliminary Report

Quantitative evaluation of exercise Tl-201 myocardial scintigraphy was carried out to determine the effect of transluminal coronary angioplasty (TCA) in 15 patients with critical coronary artery stenoses (_??_70%). Thirteen lesions were successfully dilated (reduction in stenosis by more than 30%);...

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Bibliographic Details
Published in:Japanese Heart Journal Vol. 24; no. 6; pp. 891 - 907
Main Authors: KANEMOTO, Nariaki, HÖR, Gustav, KOBER, Gisbert, KALTENBACH, Mertin
Format: Journal Article
Language:English
Published: International Heart Journal Association 1983
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Summary:Quantitative evaluation of exercise Tl-201 myocardial scintigraphy was carried out to determine the effect of transluminal coronary angioplasty (TCA) in 15 patients with critical coronary artery stenoses (_??_70%). Thirteen lesions were successfully dilated (reduction in stenosis by more than 30%); two were unsuccessful. Calculated indices from Tl-201 myocardial scintigraphy, using a semi-automatic computer image processing system, included washout factor (WF), vitality index (VI) and redistribution factor (RDF). No changes were noted in WF before and after dilatation. The VI increased in successfully dilated patients from 66.3±8.5% (mean±SD) to 77.8±10.9% (p<0.001) in the areas perfused by the vessels containing the lesions. The RDF decreased significantly after dilatation from 4.4±6.1% to 1.2±2.8% (p<0.05) 1 hour after exercise and from 10.4±7.5% to 4.1±4.2% (p<0.01) 3-4 hours after exercise. From these results, we conclude that the perfusion of ischemic areas distal to critical coronary artery stenoses improves following successful dilatation. Tl-201 myocardial scintigraphy was shown to be very useful in the evaluation of TCA.
ISSN:0021-4868
1348-673X
DOI:10.1536/ihj.24.891