Search Results - "KALLIO, J"

Ethos at stake: Performance management and academic work in universities by Kallio, Kirsi-Mari, Kallio, Tomi J, Tienari, Janne, Hyvönen, Timo

“…Higher education has been subject to substantial reforms as new forms of performance management are implemented in universities across the world. Extant…”
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Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies by Moilanen, Anu-Maarit, Riikonen, Reetta, Oksala, Riikka, Ravanti, Laura, Aho, Eija, Wohlfahrt, Gerd, Nykänen, Pirjo S., Törmäkangas, Olli P., Palvimo, Jorma J., Kallio, Pekka J.

“…Activation of androgen receptor (AR) is crucial for prostate cancer growth. Remarkably, also castration-resistant prostate cancer (CRPC) is dependent on…”
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Sensitivity of Erythrocyte Sedimentation Rate and C-reactive Protein in Childhood Bone and Joint Infections by Pääkkönen, Markus, Kallio, Markku J. T., Kallio, Pentti E., Peltola, Heikki

“…In addition to the examination of clinical signs, several laboratory markers have been measured for diagnostics and monitoring of pediatric septic bone and…”
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Short- Versus Long-term Antimicrobial Treatment for Acute Hematogenous Osteomyelitis of Childhood: Prospective, Randomized Trial on 131 Culture-positive Cases by PELTOLA, Heikki, PÄÄKKÖNEN, Markus, KALLIO, Pentti, KALLIO, Markku J. T

“…Considerable uncertainty exists on the optimal duration of antimicrobials for acute hematogenous osteomyelitis (AHOM) in children. Often they are administered…”
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Prospective, Randomized Trial of 10 Days versus 30 Days of Antimicrobial Treatment, Including a Short-Term Course of Parenteral Therapy, for Childhood Septic Arthritis by Peltola, Heikki, Pääkkönen, Markus, Kallio, Pentti, Kallio, Markku J. T.

“…Background. The standard treatment for septic arthritis in children is antimicrobials for several weeks (initially administered intravenously) and arthrotomy…”
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Wood Decay Detection in Norway Spruce Forests Based on Airborne Hyperspectral and ALS Data by Dalponte, Michele, Kallio, Alvar J. I., Ørka, Hans Ole, Næsset, Erik, Gobakken, Terje

“…Wood decay caused by pathogenic fungi in Norway spruce forests causes severe economic losses in the forestry sector, and currently no efficient methods exist…”
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MYC-Induced miR-203b-3p and miR-203a-3p Control Bcl-xL Expression and Paclitaxel Sensitivity in Tumor Cells by Aakko, Sofia, Straume, Anne Hege, Birkeland, Einar Elvbakken, Chen, Ping, Qiao, Xi, 'Lønning, Per Eystein', Kallio, Marko J.

“…Taxanes are chemotherapeutic agents used in the treatment of solid tumors, particularly of breast, ovarian, and lung origin. However, patients show divergent…”
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Long-term performance of a polyamide-12-based fuel line with a thin poly(ethylene-co-tetrafluoroethylene) (ETFE) inner layer exposed to bio- and petroleum diesel by Wei, Xin-Feng, Kallio, Kai J., Bruder, Stefan, Bellander, Martin, Gedde, Ulf W., Hedenqvist, Mikael S.

“…The long-term performance of a polyamide-12 (PA12)-based (bio)diesel fuel line/pipe with a thin poly(ethylene-co-tetrafluoroethylene) (ETFE) inner layer was…”
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Long-term performance of polyamide-based multilayer (bio)diesel fuel lines aged under “in-vehicle” conditions by Wei, Xin-Feng, Akhlaghi, Shahin, Kallio, Kai J., Bruder, Stefan, Bellander, Martin, Gedde, Ulf W., Hedenqvist, Mikael S.

“…The behaviour of a polyamide (PA)-based multilayer fuel pipe was investigated in “close to real” conditions using specially-designed ageing equipment with a…”
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Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis by Kallio, Marko J, McCleland, Mark L, Stukenberg, P Todd, Gorbsky, Gary J

“…How kinetochores correct improper microtubule attachments and regulate the spindle checkpoint signal is unclear. In budding yeast, kinetochores harboring…”
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Altered TUBB3 expression contributes to the epothilone response of mitotic cells by Narvi, E, Jaakkola, K, Winsel, S, Oetken-Lindholm, C, Halonen, P, Kallio, L, Kallio, M J

“…Background: Epothilones are a novel group of microtubule (mt) targeting cancer drugs that bind to the β -subunit of the αβ -tubulin dimer. Epothilones inhibit…”
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Age-related decreases in motor unit discharge rate and force control during isometric plantar flexion by Kallio, J, Søgaard, K, Avela, J, Komi, P, Selänne, H, Linnamo, V

“…Abstract Aging is related to multiple changes in muscle physiology and function. Previous findings concerning the effects of aging on motor unit discharge rate…”
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Performance of glass fiber reinforced polyamide composites exposed to bioethanol fuel at high temperature by Wei, Xin-Feng, Kallio, Kai J., Olsson, Richard T., Hedenqvist, Mikael S.

“…The increasing use of bioethanol fuel, as a promising carbon-neutral alternative to petroleum-based gasoline, has raised concerns on compatibility issues…”
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Novel non-β-lactam inhibitor of β-lactamase TEM-171 based on acylated phenoxyaniline by Grigorenko, V.G., Andreeva, I.P., Rubtsova, M.Yu, Deygen, I.M., Antipin, R.L., Majouga, A.G., Egorov, A.M., Beshnova, D.A., Kallio, J., Hackenberg, C., Lamzin, V.S.

“…The microbial resistance to antibiotics is a genuine global threat. Consequently, a search of new inhibitors remains of acute importance due to the increasing…”
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Clindamycin vs. first-generation cephalosporins for acute osteoarticular infections of childhood-a prospective quasi-randomized controlled trial by Peltola, H., Pääkkönen, M., Kallio, P., Kallio, M.J.T.

“…No sufficiently powered trial has examined two antimicrobials in acute osteoarticular infections of childhood. We conducted a prospective, multicentre,…”
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Structure–Function Studies of a Melanocarpus albomyces Laccase Suggest a Pathway for Oxidation of Phenolic Compounds by Kallio, J.P., Auer, S., Jänis, J., Andberg, M., Kruus, K., Rouvinen, J., Koivula, A., Hakulinen, N.

“…Melanocarpus albomyces laccase crystals were soaked with 2,6-dimethoxyphenol, a common laccase substrate. Three complex structures from different soaking times…”
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A near atomic resolution structure of a Melanocarpus albomyces laccase by Hakulinen, N., Andberg, M., Kallio, J., Koivula, A., Kruus, K., Rouvinen, J.

“…We have solved a crystal structure from Melanocarpus albomyces laccase expressed in the filamentous fungus Trichoderma reesei (rMaL) at 1.3 Å resolution by…”
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Polo-like Kinase 1 Creates the Tension-Sensing 3F3/2 Phosphoepitope and Modulates the Association of Spindle-Checkpoint Proteins at Kinetochores by Ahonen, Leena J., Kallio, Marko J., Daum, John R., Bolton, Margaret, Manke, Isaac A., Yaffe, Michael B., Stukenberg, P. Todd, Gorbsky, Gary J.

“…Background: In mitosis, a mechanochemical system recognizes tension that is generated by bipolar microtubule attachment to sister kinetochores. This is…”
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The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity by McCleland, Mark L, Gardner, Richard D, Kallio, Marko J, Daum, John R, Gorbsky, Gary J, Burke, Daniel J, Stukenberg, P Todd

“…We show that the Xenopus homologs of Ndc80/Tid3/HEC1 (xNdc80) and Nuf2/MPP1/Him-10 (xNuf2) proteins physically interact in a 190-kD complex that associates…”
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Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo by Winsel, S, Mäki-Jouppila, J, Tambe, M, Aure, M R, Pruikkonen, S, Salmela, A-L, Halonen, T, Leivonen, S-K, Kallio, L, Børresen-Dale, A-L, Kallio, M J

“…Background: Optimal expression and proper function of key mitotic proteins facilitate control and repair processes that aim to prevent loss or gain of…”
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