Search Results - "KALINOWSKI, Jorn"

Synthetic Biology Driven Biosynthesis of Unnatural Tropolone Sesquiterpenoids by Schotte, Carsten, Li, Lei, Wibberg, Daniel, Kalinowski, Jörn, Cox, Russell J.

“…Tropolone sesquiterpenoids (TS) are an intriguing family of biologically active fungal meroterpenoids that arise through a unique intermolecular hetero…”
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Comprehensive analysis of the Corynebacterium glutamicum transcriptome using an improved RNAseq technique by Pfeifer-Sancar, Katharina, Mentz, Almut, Rückert, Christian, Kalinowski, Jörn

“…The use of RNAseq to resolve the transcriptional organization of an organism was established in recent years and also showed the complexity and dynamics of…”
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Whole genome sequencing versus traditional genotyping for investigation of a Mycobacterium tuberculosis outbreak: a longitudinal molecular epidemiological study by Roetzer, Andreas, Diel, Roland, Kohl, Thomas A, Rückert, Christian, Nübel, Ulrich, Blom, Jochen, Wirth, Thierry, Jaenicke, Sebastian, Schuback, Sieglinde, Rüsch-Gerdes, Sabine, Supply, Philip, Kalinowski, Jörn, Niemann, Stefan

“…Understanding Mycobacterium tuberculosis (Mtb) transmission is essential to guide efficient tuberculosis control strategies. Traditional strain typing lacks…”
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Updating benchtop sequencing performance comparison by Jünemann, Sebastian, Sedlazeck, Fritz Joachim, Prior, Karola, Albersmeier, Andreas, John, Uwe, Kalinowski, Jörn, Mellmann, Alexander, Goesmann, Alexander, von Haeseler, Arndt, Stoye, Jens, Harmsen, Dag

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The redox-sensing MarR-type repressor HypS controls hypochlorite and antimicrobial resistance in Mycobacterium smegmatis by Tung, Quach Ngoc, Busche, Tobias, Van Loi, Vu, Kalinowski, Jörn, Antelmann, Haike

“…MarR-family transcription factors often control antioxidant enzymes, multidrug efflux pumps or virulence factors in bacterial pathogens and confer resistance…”
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Transcriptional Regulation of the Vanillate Utilization Genes (vanABK Operon) of Corynebacterium glutamicum by VanR, a PadR-Like Repressor by Morabbi Heravi, Kambiz, Lange, Julian, Watzlawick, Hildegard, Kalinowski, Jörn, Altenbuchner, Josef

“…Corynebacterium glutamicum is able to utilize vanillate, the product of lignin degradation, as the sole carbon source. The vanillate utilization components are…”
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Actinoplanes oblitus sp. nov., producing the glycopeptide antibiotic A477 by Yushchuk, Oleksandr, Binda, Elisa, Rückert-Reed, Christian, Berini, Francesca, Fedorenko, Victor, Kalinowski, Jörn, Marinelli, Flavia

“…In 1973, Eli Lilly and Company described the filamentous actinomycete producing the glycopeptide antibiotic A477 as an species on the basis of its…”
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Staphylococcus aureus adapts to the immunometabolite itaconic acid by inducing acid and oxidative stress responses including S-bacillithiolations and S-itaconations by Loi, Vu Van, Busche, Tobias, Kuropka, Benno, Müller, Susanne, Methling, Karen, Lalk, Michael, Kalinowski, Jörn, Antelmann, Haike

“…Staphylococcus aureus is a major pathogen, which has to defend against reactive oxygen and electrophilic species encountered during infections. Activated…”
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The transcriptomic landscape of Magnetospirillum gryphiswaldense during magnetosome biomineralization by Riese, Cornelius N, Wittchen, Manuel, Jérôme, Valérie, Freitag, Ruth, Busche, Tobias, Kalinowski, Jörn, Schüler, Dirk

“…One of the most complex prokaryotic organelles are magnetosomes, which are formed by magnetotactic bacteria as sensors for navigation in the Earth's magnetic…”
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Towards a 'chassis' for bacterial magnetosome biosynthesis: genome streamlining of Magnetospirillum gryphiswaldense by multiple deletions by Zwiener, Theresa, Dziuba, Marina, Mickoleit, Frank, Rückert, Christian, Busche, Tobias, Kalinowski, Jörn, Uebe, René, Schüler, Dirk

“…Because of its tractability and straightforward cultivation, the magnetic bacterium Magnetospirillum gryphiswaldense has emerged as a model for the analysis of…”
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Integration event induced changes in recombinant protein productivity in Pichia pastoris discovered by whole genome sequencing and derived vector optimization by Schwarzhans, Jan-Philipp, Wibberg, Daniel, Winkler, Anika, Luttermann, Tobias, Kalinowski, Jörn, Friehs, Karl

“…The classic AOX1 replacement approach is still one of the most often used techniques for expression of recombinant proteins in the methylotrophic yeast Pichia…”
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Streptomyces coriariae sp. nov., a novel streptomycete isolated from actinorhizal nodules of Coriaria intermedia by Berckx, Fede, Bandong, Cyndi Mae, Wibberg, Daniel, Kalinowski, Jörn, Willemse, Joost, Brachmann, Andreas, Simbahan, Jessica, Pawlowski, Katharina

“…An actinobacterial strain, CMB-FB, was isolated from surface-sterilized root nodules of a plant growing along Halsema Highway in the province of Benguet…”
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Recombinant expression and characterization of novel P450s from Actinosynnema mirum by Schmitz, Lisa Marie, Hageneier, Felix, Rosenthal, Katrin, Busche, Tobias, Brandt, David, Kalinowski, Jörn, Lütz, Stephan

“…[Display omitted] Cytochrome P450 monooxygenases (P450s) are the major contributor in the metabolism of xenobiotics, including therapeutic agents. Thus, P450s…”
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Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum by Kulis‐Horn, Robert K., Persicke, Marcus, Kalinowski, Jörn

“…Summary l‐Histidine biosynthesis is an ancient metabolic pathway present in bacteria, archaea, lower eukaryotes, and plants. For decades l‐histidine…”
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An environmental bacterial taxon with a large and distinct metabolic repertoire by Wilson, Micheal C., Mori, Tetsushi, Rückert, Christian, Uria, Agustinus R., Helf, Maximilian J., Takada, Kentaro, Gernert, Christine, Steffens, Ursula A. E., Heycke, Nina, Schmitt, Susanne, Rinke, Christian, Helfrich, Eric J. N., Brachmann, Alexander O., Gurgui, Cristian, Wakimoto, Toshiyuki, Kracht, Matthias, Crüsemann, Max, Hentschel, Ute, Abe, Ikuro, Matsunaga, Shigeki, Kalinowski, Jörn, Takeyama, Haruko, Piel, Jörn

“…Cultivated bacteria such as actinomycetes are a highly useful source of biomedically important natural products. However, such ‘talented’ producers represent…”
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The AGXX® Antimicrobial Coating Causes a Thiol-Specific Oxidative Stress Response and Protein S -bacillithiolation in Staphylococcus aureus by Loi, Vu Van, Busche, Tobias, Preuß, Thalia, Kalinowski, Jörn, Bernhardt, Jörg, Antelmann, Haike

“…Multidrug-resistant pathogens, such as methicillin-resistant (MRSA) pose an increasing health burden and demand alternative antimicrobials to treat bacterial…”
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Transcriptional response of Corynebacterium glutamicum ATCC 13032 to hydrogen peroxide stress and characterization of the OxyR regulon by Milse, Johanna, Petri, Kathrin, Rückert, Christian, Kalinowski, Jörn

“…•The dynamic reaction of the cellular regulatory networks in response to H2O2 is shown.•The regulatory network of OxyR in C. glutamicum is extended to a total…”
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Pseudomonas paracarnis sp. nov., isolated from refrigerated beef by Lick, Sonja, Wibberg, Daniel, Winkler, Annika, Blom, Jochen, Grimmler, Christina, Goesmann, Alexander, Kalinowski, Jörn, Kröckel, Lothar

“…During a project focusing on the diversity of meat microbiota associated with beef ripening, a strain was isolated exhibiting high 16S rRNA gene sequence…”
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An assemblage of Frankia Cluster II strains from California contains the canonical nod genes and also the sulfotransferase gene nodH by Nguyen, Thanh Van, Wibberg, Daniel, Battenberg, Kai, Blom, Jochen, Vanden Heuvel, Brian, Berry, Alison M, Kalinowski, Jörn, Pawlowski, Katharina

“…The ability to establish root nodule symbioses is restricted to four different plant orders. Soil actinobacteria of the genus Frankia can establish a symbiotic…”
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Targeted genome editing in the rare actinomycete Actinoplanes sp. SE50/110 by using the CRISPR/Cas9 System by Wolf, Timo, Gren, Tetiana, Thieme, Eric, Wibberg, Daniel, Zemke, Till, Pühler, Alfred, Kalinowski, Jörn

“…•The functionality of CRISPR/Cas9 in Actinoplanes sp. SE50/110 was proven.•First description of genome editing with CRISPR/Cas9 in rare actinomycetes.•A clear…”
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