Search Results - "KAKUMA, T"

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  1. 1

    Expression of activated signal transducer and activator of transcription-3 predicts poor prognosis in cervical squamous-cell carcinoma by Takemoto, S, Ushijima, K, Kawano, K, Yamaguchi, T, Terada, A, Fujiyoshi, N, Nishio, S, Tsuda, N, Ijichi, M, Kakuma, T, Kage, M, Hori, D, Kamura, T

    Published in British journal of cancer (15-09-2009)
    “…Background: Stat3 is a member of the Janus-activated kinase/STAT signalling pathway. It normally resides in the cytoplasm and can be activated through…”
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  2. 2

    Pre‐treatment CD8+ tumour‐infiltrating lymphocyte density predicts distant metastasis after definitive treatment in patients with stage III/IV hypopharyngeal squamous cell carcinoma by Ono, T., Azuma, K., Kawahara, A., Akiba, J., Kakuma, T., Chitose, S., Umeno, H.

    Published in Clinical otolaryngology (01-10-2018)
    “…Objectives Although inflammatory markers, such as the neutrophil‐to‐lymphocyte ratio, platelet‐to‐lymphocyte ratio and local immune markers have been shown to…”
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  3. 3

    Determinants of outcomes following acute child encephalopathy and encephalitis: pivotal effect of early and delayed cooling by Kawano, G, Iwata, O, Iwata, S, Kawano, K, Obu, K, Kuki, I, Rinka, H, Shiomi, M, Yamanouchi, H, Kakuma, T, Takashima, S, Matsuishi, T

    Published in Archives of disease in childhood (01-10-2011)
    “…Background Acute encephalopathy/encephalitis is one of the most important causatives of mortality and neurological deficit during childhood. The aim of this…”
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  4. 4

    Hypothalamic Brain-Derived Neurotrophic Factor Regulates Glucagon Secretion Mediated by Pancreatic Efferent Nerves by Gotoh, K., Masaki, T., Chiba, S., Ando, H., Fujiwara, K., Shimasaki, T., Mitsutomi, K., Katsuragi, I., Kakuma, T., Sakata, T., Yoshimatsu, H.

    Published in Journal of neuroendocrinology (01-03-2013)
    “…Understanding the molecular mechanism of the regulation of glucagon secretion is critical for treating the dysfunction of α cells observed in diabetes…”
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  5. 5

    A c-fos-Monomeric Red Fluorescent Protein 1 Fusion Transgene is Differentially Expressed in Rat Forebrain and Brainstem after Chronic Dehydration and Rehydration by Yoshimura, M., Ohkubo, J., Katoh, A., Ohno, M., Ishikura, T., Kakuma, T., Yoshimatsu, H., Murphy, D., Ueta, Y.

    Published in Journal of neuroendocrinology (01-05-2013)
    “…We have previously shown that an acute osmotic stimulation induces the expression of a c‐fos and monomeric red fluorescent protein 1 (mRFP1) fusion transgene…”
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  6. 6

    Differential expression of human chorionic gonadotropin (hCG) glycosylation isoforms in failing and continuing pregnancies: preliminary characterization of the hyperglycosylated hCG epitope by Kovalevskaya, G, Birken, S, Kakuma, T, Ozaki, N, Sauer, M, Lindheim, S, Cohen, M, Kelly, A, Schlatterer, J, O'Connor, JF

    Published in Journal of endocrinology (01-03-2002)
    “…Human chorionic gonadotropin (hCG) glycoforms change as pregnancy progresses. We have developed an antibody (B152) which can measure a hyperglycosylated early…”
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    Hyperglycosylated HCG expression in pregnancy: Cellular origin and clinical applications by Kovalevskaya, G., Kakuma, T., Schlatterer, J., O’Connor, J.F.

    Published in Molecular and cellular endocrinology (02-01-2007)
    “…Employing a monoclonal antibody (B152) specific for a carbohydrate epitope found on a choriocarcinoma derived hCG, it was discovered that a similar hCG isoform…”
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  9. 9

    The role of leptin resistance in the lipid abnormalities of aging by WANG, ZHUO-WEI, PAN, WEN-TONG, LEE, YOUNG, KAKUMA, TETSUYA, ZHOU, YAN-TING, UNGER, ROGER H.

    Published in The FASEB journal (01-01-2001)
    “…ABSTRACT Leptin resistance has been implicated in the pathogenesis of obesity‐related complications involving abnormalities of lipid metabolism that resemble…”
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  10. 10

    Therapeutic hypothermia can be induced and maintained using either commercial water bottles or a “phase changing material” mattress in a newborn piglet model by Iwata, S, Iwata, O, Olson, L, Kapetanakis, A, Kato, T, Evans, S, Araki, Y, Kakuma, T, Matsuishi, T, Setterwall, F, Lagercrantz, H, Robertson, N J

    Published in Archives of disease in childhood (01-05-2009)
    “…Background:Therapeutic hypothermia, a safe and effective treatment for neonatal encephalopathy in an intensive care setting, is not available in low-resource…”
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  11. 11

    Early pregnancy human chorionic gonadotropin (hCG) isoforms measured by an immunometric assay for choriocarcinoma-like hCG by Kovalevskaya, G, Birken, S, Kakuma, T, O'Connor, JF

    Published in Journal of endocrinology (01-04-1999)
    “…Human chorionic gonadotropin (hCG) exhibits molecular heterogeneity in both its protein and carbohydrate moieties. This communication describes changes in hCG…”
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  12. 12

    Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis by SAKUMI, K, FURUICHI, M, TSUZUKI, T, KAKUMA, T, KAWABATA, S.-I, SEKIGUCHI, M

    Published in The Journal of biological chemistry (05-11-1993)
    “…8-Oxoguanine (8-oxo-7, 8-dihydroguanine) is produced in DNA, as well as in nucleotide pools of cells, by active oxygen species normally formed during cellular…”
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  13. 13

    Role of leptin in peroxisome proliferator-activated receptor gamma coactivator-1 expression by Kakuma, T, Wang, Z W, Pan, W, Unger, R H, Zhou, Y T

    Published in Endocrinology (Philadelphia) (01-12-2000)
    “…Peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1), a cold-induced protein expressed in brown adipose tissue (BAT), plays a role in…”
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  14. 14

    Smoking is associated with insulin resistance and cardiovascular autonomic dysfunction in type 2 diabetic patients by Anan, F., Takahashi, N., Shinohara, T., Nakagawa, M., Masaki, T., Katsuragi, I., Tanaka, K., Kakuma, T., Yonemochi, H., Eshima, N., Saikawa, T., Yoshimatsu, H.

    Published in European journal of clinical investigation (01-07-2006)
    “…Background  Smoking and cardiovascular autonomic dysfunction are associated with high mortality in type 2 diabetic patients. This study tested the hypothesis…”
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  15. 15

    Results of Treatment of 112 Cases of Primary CNS Lymphoma by Yamanaka, Ryuya, Morii, Ken, Shinbo, Yoshikatsu, Homma, Junpei, Sano, Masakazu, Tsuchiya, Naoto, Yajima, Naoki, Tamura, Tetsuro, Hondoh, Hiroaki, Takahashi, Hitoshi, Kakuma, Tatsuyuki, Tanaka, Ryuichi

    Published in Japanese journal of clinical oncology (01-05-2008)
    “…Background Chemotherapy with or without radiotherapy is the mainstay of treatment for primary central nervous system lymphoma (PCNSL). High-dose methotrexate…”
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  16. 16

    Beneficial effects of leukotriene receptor antagonists in the prevention of cedar pollinosis in a community setting by Yonekura, S, Okamoto, Y, Okubo, K, Okawa, T, Gotoh, M, Suzuki, H, Kakuma, T, Horiguchi, S, Hanazawa, T, Konno, A, Okuda, M

    “…In recent years, many countries have experienced an increase in the prevalence of allergic rhinitis. No effective approach is currently available to prevent…”
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  17. 17

    Streptozotocin treatment upregulates uncoupling protein 3 expression in the rat heart by HIDAKA, S, KAKUMA, T, YOSHIMATSU, H, SAKINO, H, FUKUCHI, S, SAKATA, T

    Published in Diabetes (New York, N.Y.) (01-02-1999)
    “…Streptozotocin treatment upregulates uncoupling protein 3 expression in the rat heart. S Hidaka , T Kakuma , H Yoshimatsu , H Sakino , S Fukuchi and T Sakata…”
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    P3121Cancer therapeutics-related heart failure from a cohort study using big data of electronic health record in Japan by Nohara, S, Shibata, T, Ishi, K, Obara, H, Miyamoto, T, Kakuma, T, Fukumoto, Y

    Published in European heart journal (01-10-2019)
    “…Abstract Background The prognosis of cancer patients has been improved partly because of the progress in cancer therapy, which increases the cancer survivors…”
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