Search Results - "KAKUMA, T"
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Expression of activated signal transducer and activator of transcription-3 predicts poor prognosis in cervical squamous-cell carcinoma
Published in British journal of cancer (15-09-2009)“…Background: Stat3 is a member of the Janus-activated kinase/STAT signalling pathway. It normally resides in the cytoplasm and can be activated through…”
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Pre‐treatment CD8+ tumour‐infiltrating lymphocyte density predicts distant metastasis after definitive treatment in patients with stage III/IV hypopharyngeal squamous cell carcinoma
Published in Clinical otolaryngology (01-10-2018)“…Objectives Although inflammatory markers, such as the neutrophil‐to‐lymphocyte ratio, platelet‐to‐lymphocyte ratio and local immune markers have been shown to…”
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Determinants of outcomes following acute child encephalopathy and encephalitis: pivotal effect of early and delayed cooling
Published in Archives of disease in childhood (01-10-2011)“…Background Acute encephalopathy/encephalitis is one of the most important causatives of mortality and neurological deficit during childhood. The aim of this…”
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Hypothalamic Brain-Derived Neurotrophic Factor Regulates Glucagon Secretion Mediated by Pancreatic Efferent Nerves
Published in Journal of neuroendocrinology (01-03-2013)“…Understanding the molecular mechanism of the regulation of glucagon secretion is critical for treating the dysfunction of α cells observed in diabetes…”
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A c-fos-Monomeric Red Fluorescent Protein 1 Fusion Transgene is Differentially Expressed in Rat Forebrain and Brainstem after Chronic Dehydration and Rehydration
Published in Journal of neuroendocrinology (01-05-2013)“…We have previously shown that an acute osmotic stimulation induces the expression of a c‐fos and monomeric red fluorescent protein 1 (mRFP1) fusion transgene…”
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Differential expression of human chorionic gonadotropin (hCG) glycosylation isoforms in failing and continuing pregnancies: preliminary characterization of the hyperglycosylated hCG epitope
Published in Journal of endocrinology (01-03-2002)“…Human chorionic gonadotropin (hCG) glycoforms change as pregnancy progresses. We have developed an antibody (B152) which can measure a hyperglycosylated early…”
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Influence of external load level on scapula upward rotation during elevation
Published in Physiotherapy (01-05-2015)Get full text
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Hyperglycosylated HCG expression in pregnancy: Cellular origin and clinical applications
Published in Molecular and cellular endocrinology (02-01-2007)“…Employing a monoclonal antibody (B152) specific for a carbohydrate epitope found on a choriocarcinoma derived hCG, it was discovered that a similar hCG isoform…”
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The role of leptin resistance in the lipid abnormalities of aging
Published in The FASEB journal (01-01-2001)“…ABSTRACT Leptin resistance has been implicated in the pathogenesis of obesity‐related complications involving abnormalities of lipid metabolism that resemble…”
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Therapeutic hypothermia can be induced and maintained using either commercial water bottles or a “phase changing material” mattress in a newborn piglet model
Published in Archives of disease in childhood (01-05-2009)“…Background:Therapeutic hypothermia, a safe and effective treatment for neonatal encephalopathy in an intensive care setting, is not available in low-resource…”
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Early pregnancy human chorionic gonadotropin (hCG) isoforms measured by an immunometric assay for choriocarcinoma-like hCG
Published in Journal of endocrinology (01-04-1999)“…Human chorionic gonadotropin (hCG) exhibits molecular heterogeneity in both its protein and carbohydrate moieties. This communication describes changes in hCG…”
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Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis
Published in The Journal of biological chemistry (05-11-1993)“…8-Oxoguanine (8-oxo-7, 8-dihydroguanine) is produced in DNA, as well as in nucleotide pools of cells, by active oxygen species normally formed during cellular…”
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Role of leptin in peroxisome proliferator-activated receptor gamma coactivator-1 expression
Published in Endocrinology (Philadelphia) (01-12-2000)“…Peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1), a cold-induced protein expressed in brown adipose tissue (BAT), plays a role in…”
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Smoking is associated with insulin resistance and cardiovascular autonomic dysfunction in type 2 diabetic patients
Published in European journal of clinical investigation (01-07-2006)“…Background Smoking and cardiovascular autonomic dysfunction are associated with high mortality in type 2 diabetic patients. This study tested the hypothesis…”
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Results of Treatment of 112 Cases of Primary CNS Lymphoma
Published in Japanese journal of clinical oncology (01-05-2008)“…Background Chemotherapy with or without radiotherapy is the mainstay of treatment for primary central nervous system lymphoma (PCNSL). High-dose methotrexate…”
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Beneficial effects of leukotriene receptor antagonists in the prevention of cedar pollinosis in a community setting
Published in Journal of investigational allergology & clinical immunology (2009)“…In recent years, many countries have experienced an increase in the prevalence of allergic rhinitis. No effective approach is currently available to prevent…”
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Streptozotocin treatment upregulates uncoupling protein 3 expression in the rat heart
Published in Diabetes (New York, N.Y.) (01-02-1999)“…Streptozotocin treatment upregulates uncoupling protein 3 expression in the rat heart. S Hidaka , T Kakuma , H Yoshimatsu , H Sakino , S Fukuchi and T Sakata…”
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Prevalence and prognosis in cancer therapy-related cardiovascular diseases from big data of electronic health record in Japan
Published in European heart journal (01-11-2020)Get full text
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P3121Cancer therapeutics-related heart failure from a cohort study using big data of electronic health record in Japan
Published in European heart journal (01-10-2019)“…Abstract Background The prognosis of cancer patients has been improved partly because of the progress in cancer therapy, which increases the cancer survivors…”
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