Search Results - "KAJIWARA, Naemi"
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Anti-hyperglycemic Effect of Long-Term Bis(hinokitiolato)zinc Complex ([Zn(hkt)2]) Ingestion on Insulin Resistance and Pancreatic Islet Cells Protection in Type 2 Diabetic KK-Ay Mice
Published in Biological & pharmaceutical bulletin (01-03-2017)“…Zinc (Zn) is a trace element with anti-diabetes mellitus (anti-DM) effects. Zn complexes exhibit stronger insulin-like activity than Zn ions…”
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Insulinomimetic Zn(II) Complexes as Evaluated by Both Glucose-Uptake Activity and Inhibition of Free Fatty Acids Release in Isolated Rat Adipocytes
Published in Chemical & Pharmaceutical Bulletin (01-08-2008)“…We prepared 4 new Zn(II) complexes with Zn(O4), Zn(N2O2), and Zn(S2O2) coordination modes and evaluated their insulinomimetic activities in an in vitro study…”
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Antidiabetic effect of the α-lipoic acid γ-cyclodextrin complex
Published in Journal of Clinical Biochemistry and Nutrition (01-09-2014)“…In recent years, the number of patients suffering from diabetes mellitus has been increasing worldwide. In particular, type 2 diabetes mellitus, a…”
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4
In Vitro Alpha-glucosidase Inhibitory Effect of Zn(II) Complex with 6-Methyl-2-picolinmethylamide
Published in Chemical & pharmaceutical bulletin (01-04-2005)“…We found alpha-glucosidase inhibitory effect of Zn(II) complex with 6-methyl-2-picolinmethylamide (6mpa-ma) which showed the highest blood glucose lowering…”
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5
Antidiabetic Activity of Zn(II) Complexes with a Derivative of L-Glutamine
Published in Bulletin of the Chemical Society of Japan (01-06-2005)“…The insulinomimetic activity of zinc(II) complexes Zn(gln-m)2 and Zn(gln-e)2, respectively, with L-γ-glutamyl-methylamide (gln-m) and -ethylamide (theanine:…”
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6
Structure–Activity Relationship of Insulinomimetic Activity of Zinc(II) Complexes with Pyridine-2-sulfonic Acid Derivatives
Published in Bulletin of the Chemical Society of Japan (15-03-2007)“…We prepared zinc(II) complexes with a series of mono-methyl-substituted pyridine-2-sulfonic acid derivatives to clarify the relationship between the structure…”
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New Bioactive Zinc(II) Complexes with Peptides and Their Derivatives: Synthesis, Structure, and In Vitro Insulinomimetic Activity
Published in Bulletin of the Chemical Society of Japan (01-05-2004)“…Four Zn(II) complexes with dipeptides and three new Zn(II) complexes with pseudo-tripeptides were prepared and a complex, [Zn(glythr)2]n, was revealed to have…”
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Isomeric effects of anti-diabetic α-lipoic acid with γ-cyclodextrin
Published in Life sciences (1973) (01-09-2015)“…Previous studies reported the anti-diabetic effects of α-lipoic acid (αLA) isomers: racemic-αLA, R-αLA, or S-αLA. Previously, we examined the anti-diabetic…”
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Ground electric field effects on rats and sparrows : Seismic anomalous animal behaviors (SAABs)
Published in JPN J APPL PHYS PART 1 REGUL PAP SHORT NOTE REV PAP (1996)“…Electric field effects on behaviors of albino rats, Mongolian gerbils (sand rats), hair-footed Djungarian hamsters, guinea pigs and red sparrows (Avadavat)…”
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10
Normalizing Effect of Zinc(II) Complex with 6-Ethoxy Picolinic Acid on Blood Glucose Levels in KK-Ay Mice
Published in Biomedical Research on Trace Elements (2006)“…We examined normalizing effect for blood glucose levels of zinc(II) complex with 6-ethoxy picolinic acid (Zn(6-EtOpa)2) on KK-Ay mice which used in this study…”
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11
Improving effects of Zn(II) Complex with Papaya Powder on Model Animals of Type 2 Diabetes Mellitus
Published in Biomedical Research on Trace Elements (2006)“…Zn(II) complex is known to have insulinomimetic activity at a lower concentration than the simple Zn ion. In this study, the effects of Zn(II) complex with…”
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12
Dyslipidemia in diabetes: a population-based study in Bali
Published in International journal of general medicine (01-09-2019)“…To establish the lipid pattern in subjects with diabetes mellitus (DM) and factors that are correlated with insulin resistance and lipid disorders in a…”
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13
Anti-hyperglycemic Effect of Long-Term Bis(hinokitiolato)zinc Complex ([Zn(hkt) 2 ]) Ingestion on Insulin Resistance and Pancreatic Islet Cells Protection in Type 2 Diabetic KK-A y Mice
Published in Biological & pharmaceutical bulletin (2017)“…Zinc (Zn) is a trace element with anti-diabetes mellitus (anti-DM) effects. Zn complexes exhibit stronger insulin-like activity than Zn ions…”
Get full text
Journal Article -
14
Insulinomimetic activity of zinc (II) complexes with halogenated picolinic acids
Published in Biomedical Research on Trace Elements (2004)“…We prepared six new zinc(II) complexes of halogenated picolinic acids with a Zn(N2O2) coordination mode and evaluated for their insulinomimetic activities by…”
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15
Antidiabetic effect of the [alpha]-lipoic acid [gamma]-cyclodextrin complex
Published in Journal of clinical biochemistry and nutrition (01-09-2014)“…In recent years, the number of patients suffering from diabetes mellitus has been increasing worldwide. In particular, type 2 diabetes mellitus, a…”
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16
Underweight is an important risk factor for coronary heart disease in the population of Ceningan Island, Bali
Published in Diabetes & vascular disease research (01-01-2012)“…A study on the prevalence of coronary heart disease (CHD) and its risk factors in Ceningan Island was conducted. The prevalence of CHD was 11.5%. Older age…”
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Effects of Zn(II) complex with vitamins C and U, and carnitine on metabolic syndrome model rats
Published in Metallomics (01-07-2011)“…The insulinomimetic activity of a Zn(ii) complex is reported. The effects of the Zn(ii) complex with ascorbic acid (Vitamin C; VC), methylmethionine sulfonium…”
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2型糖尿病モデルマウスKK-Ayにおけるエトキシピコリン酸亜鉛(II)錯体の血糖上昇抑制作用
Published in BIOMEDICAL RESEARCH ON TRACE ELEMENTS (2006)“…「はじめに」糖尿病は膵臓に点在する内分泌器官, β細胞から分泌されるインスリンの相対的または絶対的不足によって引き起こされ, 主として糖質の代謝障害によって高血糖と尿糖を生じる疾患である1). 2002年の世界保健機構(WHO)の報告によると, 2000年の糖尿病患者数は全世界で約1億7千7百万人,…”
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亜鉛含有食品としてのパパイア粉末/亜鉛(II)錯体の2型糖尿病病態改善効果
Published in BIOMEDICAL RESEARCH ON TRACE ELEMENTS (2006)“…生活習慣病の一つである2型糖尿病の治療の基本は食事療法と運動療法である. しかしながら, 高血糖状態の持続が2型糖尿病合併症発症の最大のリスクファクターである血管障害の原因となる事から1), 速やかな血糖値是正の為, 様々な血糖降下剤が研究, 開発され臨床で使用されてきた2-5). 加えて,…”
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20
Increase of visceral fat area in Indonesians and Japanese with normal BMI
Published in Diabetes research and clinical practice (01-09-2007)“…Abstract We compared the visceral fat accumulation between Indonesians and Japanese. Non-obese (25 > BMI ≥ 18.5) men aged between their 20s and 50s were…”
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