Search Results - "KAJIMOTO, Tetsuya"
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Metal-Free Synthesis of Acyl Glycosides and Application to Oligosaccharide Synthesis
Published in Organic letters (16-12-2022)“…Oligosaccharides are involved in numerous biological processes. Achieving optimal anomeric selectivity and regioselectivity remains challenging. Herein, we…”
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Effect of 1,4-Dioxane Solvent on β-Glucuronidation Using Methyl 1,2,3,4-Tetra-O-acetyl-β-D-glucuronate as the Glycosyl Donor
Published in Chemical & pharmaceutical bulletin (2024)“…A facile and selective β-D-glucuronidation of alcohols, such as (−)-menthol, cholestanol, (+)- and (−)-borneols, and 2-adamantanol, using commercially…”
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3
Facile Preparation of L-Iduronic Acid and α-L-Iduronidation Using Methyl 1,2,3,4-Tetra-O-acetyl-α-L-iduronate as Glycosyl Donor
Published in Chemical & pharmaceutical bulletin (01-09-2023)“…Methyl 1,2,3,4-tetra-O-acetyl-α-L-iduronate was prepared from methyl 1,2,3,4-tetra-O-β-D-glucuronate in two steps: Ferrier’s photobromination and subsequent…”
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N-Glycosylation of Thio-glycoside Derived from Odorless Thiols Using Hypervalent Iodine(III) Reagent
Published in Heterocycles (2021)Get full text
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The ALK‐5 inhibitor A‐83‐01 inhibits Smad signaling and epithelial‐to‐mesenchymal transition by transforming growth factor‐β
Published in Cancer science (01-11-2005)“…Transforming growth factor (TGF)‐β signaling facilitates tumor growth and metastasis in advanced cancer. Use of inhibitors of TGF‐β signaling may thus be a…”
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A Facile α-Glucuronidation Using Methyl 1,2,3,4-Tetra-O-acetyl-D-glucuronate as Glycosyl Donor
Published in Chemical & pharmaceutical bulletin (01-08-2022)“…Some terpenyl 2,3,4-tri-O-acetyl-α-D-glucuronide methyl esters were facilely synthesized from commercially available methyl…”
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Elucidation of the Relationship between CD Cotton Effects and the Absolute Configuration of Sixteen Stereoisomers of Spiroheterocyclic-Lactams
Published in Marine drugs (29-06-2018)“…As part of research to search for antitumor agents in fungi originating from marine organisms, cephalimysins E⁻L were isolated from a culture broth of that was…”
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Inhibitors against glycosidases as medicines
Published in Current topics in medicinal chemistry (2009)“…Glycosidases mediate the digestion of oligosaccharides in the small intestine as well as the processing of cell surface oligosaccharides, which play important…”
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Phenyliodine Bis(trifluoroacetate) (PIFA) as an Excellent Promoter of 2-Deoxy-2-phthalimido-1-thioglycosides in the Presence of Triflic Acid in Glycosylation Reactions
Published in European journal of organic chemistry (01-04-2015)“…A combination of phenyliodine bis(trifluoroacetate) (PIFA) and trifluoromethanesulfonic acid was found to be an effective activator for the glycosylation…”
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10
Construction of Acyclic All-Carbon Quaternary Stereocenter Based on Asymmetric Michael Addition of Chiral Amine
Published in Chemical & pharmaceutical bulletin (01-09-2021)“…Acyclic asymmetric quaternary stereocenters, which are composed of four carbon-carbon bonds, were finely constructed by utilizing a face-selective alkylation…”
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Prognostic significance of preoperative osteopenia on outcomes after gastrectomy for gastric cancer
Published in Annals of gastroenterological surgery (01-03-2023)“…Aim Osteopenia, characterized by low bone mineral density, is a potential prognostic factor for patients with cancer. The aim of this study was to clarify the…”
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Enviromentally-Benign Glycosylation Reaction Using Odorless Thio-Glycosides and Hypervalent Iodine(III) Reagent
Published in Heterocycles (2019)Get full text
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13
Glycosylation Reaction of Thioglycosides by Using Hypervalent Iodine(III) Reagent as an Excellent Promoter
Published in Chemical & pharmaceutical bulletin (2016)“…Thioglycosides are available donors in glycosylation due to the stability of the anomeric C–S bond under general reaction conditions of protection and…”
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14
N-Glycosylation Reaction of Thio-Glycoside Using Hypervalent Iodine(Ill) Reagent
Published in Heterocycles (2020)Get full text
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15
New class azaphilone produced by a marine fish-derived Chaetomium globosum. The stereochemistry and biological activities
Published in Bioorganic & medicinal chemistry (01-07-2011)“…Four new metabolites, chaetomugilins P–R and 11-epi-chaetomugilin I, were isolated from a strain of Chaetomium globosum originally obtained from the marine…”
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The Relationship between the CD Cotton Effect and the Absolute Configuration of FD-838 and Its Seven Stereoisomers
Published in Journal of organic chemistry (18-06-2010)“…Three new metabolites having a spiro-heterocyclic γ-lactam core, cephalimysins B−D (1−3), as well as FD-838 (4) were isolated from a culture broth of…”
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Three new azaphilones produced by a marine fish-derived chaetomium globosum
Published in Journal of antibiotics (01-08-2012)“…Three new metabolites, chaetomugilin S, dechloro-chaetomugilin A and dechloro-chaetomugilin D, were isolated from a strain of Chaetomium globosum originally…”
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The synthesis of [18F]pitavastatin as a tracer for hOATP using the Suzuki coupling
Published in Organic & biomolecular chemistry (28-01-2015)“…Fluorine-18 labeled radiotracers, such as [(18)F]fluorodeoxyglucose, can be used as practical diagnostic agents in positron emission tomography (PET)…”
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Andirolides H–P from the flower of andiroba (Carapa guianensis, Meliaceae)
Published in Tetrahedron (06-05-2012)“…Three new gedunins, an andirobin, three mexicanolides, and two phragmalin-type limonoids named andirolides H (1), I (2), J (3), K (4), L (5), M (6), N (7), O…”
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Isolation and Characterization of New Onionins A2 and A3 from Allium cepa, and of Onionins A1, A2, and A3 from Allium fistulosum
Published in Chemical & pharmaceutical bulletin (01-11-2014)“…In this study, the new stable sulfur-containing compounds onionins A2 (1) and A3 (2) were isolated from the acetone extracts of the bulbs of Allium cepa L. and…”
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