Search Results - "KAJI, AKIRA"

Role of ribosome recycling factor in natural termination and translational coupling as a ribosome releasing factor by Inokuchi, Yoshio, Quaglia, Fabio, Hirashima, Akikazu, Yamamoto, Yoshihiro, Kaji, Hideko, Kaji, Akira

“…The role of ribosome recycling factor (RRF) of E. coli was studied in vivo and in vitro. We used the translational coupling without the Shine-Dalgarno sequence…”
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Structural basis for aminoglycoside inhibition of bacterial ribosome recycling by Hirokawa, Go, Holton, James M, Schuwirth, Barbara S, Kaji, Hideko, Pai, Raj D, Cate, Jamie H Doudna, Borovinskaya, Maria A, Zhang, Wen, Kaji, Akira

“…Aminoglycosides are widely used antibiotics that cause messenger RNA decoding errors, block mRNA and transfer RNA translocation, and inhibit ribosome…”
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Antibiotic Overproduction by rpsL and rsmG Mutants of Various Actinomycetes by TANAKA, Yukinori, KOMATSU, Mamoru, OKAMOTO, Susumu, TOKUYAMA, Shinji, KAJI, Akira, IKEDA, Haruo, OCHI, Kozo

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Chemical and structural characterization of a model Post-Termination Complex (PoTC) for the ribosome recycling reaction: Evidence for the release of the mRNA by RRF and EF-G by Iwakura, Nobuhiro, Yokoyama, Takeshi, Quaglia, Fabio, Mitsuoka, Kaoru, Mio, Kazuhiro, Shigematsu, Hideki, Shirouzu, Mikako, Kaji, Akira, Kaji, Hideko

“…A model Post-Termination Complex (PoTC) used for the discovery of Ribosome Recycling Factor (RRF) was purified and characterized by cryo-electron microscopic…”
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3‑Fluoroazetidinecarboxylic Acids and trans,trans-3,4-Difluoroproline as Peptide Scaffolds: Inhibition of Pancreatic Cancer Cell Growth by a Fluoroazetidine Iminosugar by Liu, Zilei, Jenkinson, Sarah F, Vermaas, Tom, Adachi, Isao, Wormald, Mark R, Hata, Yukako, Kurashima, Yukiko, Kaji, Akira, Yu, Chu-Yi, Kato, Atsushi, Fleet, George W. J

“…Reverse aldol opening renders amides of 3-hydroxyazetidinecarboxylic acids (3-OH-Aze) unstable above pH 8. Aze, found in sugar beet, is mis-incorporated for…”
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Possible steps of complete disassembly of post-termination complex by yeast eEF3 deduced from inhibition by translocation inhibitors by Kurata, Shinya, Shen, Ben, Liu, Jun O, Takeuchi, Nono, Kaji, Akira, Kaji, Hideko

“…Ribosomes, after one round of translation, must be recycled so that the next round of translation can occur. Complete disassembly of post-termination ribosomal…”
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Protein Synthesis Factors (RF1, RF2, RF3, RRF, and tmRNA) and Peptidyl-tRNA Hydrolase Rescue Stalled Ribosomes at Sense Codons by Vivanco-Domínguez, Serafín, Bueno-Martínez, José, León-Avila, Gloria, Iwakura, Nobuhiro, Kaji, Akira, Kaji, Hideko, Guarneros, Gabriel

“…During translation, ribosomes stall on mRNA when the aminoacyl-tRNA to be read is not readily available. The stalled ribosomes are deleterious to the cell and…”
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Ribosome recycling step in yeast cytoplasmic protein synthesis is catalyzed by eEF3 and ATP by Kurata, Shinya, Nielsen, Klaus H., Mitchell, Sarah F., Lorsch, Jon R., Kaji, Akira, Kaji, Hideko, Yanofsky, Charles

“…After each round of protein biosynthesis, the posttermination complex (PoTC) consisting of a ribosome, mRNA, and tRNA must be disassembled into its components…”
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Visualization of Ribosome-Recycling Factor on the Escherichia coli 70S Ribosome: Functional Implications by Agrawal, Rajendra K., Sharma, Manjuli R., Kiel, Michael C., Hirokawa, Go, Booth, Timothy M., Christian M. T. Spahn, Grassucci, Robert A., Kaji, Akira, Frank, Joachim, Moore, Peter B.

“…After the termination step of protein synthesis, a deacylated tRNA and mRNA remain associated with the ribosome. The ribosome-recycling factor (RRF), together…”
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The ribosome-recycling step: consensus or controversy? by Hirokawa, Go, Demeshkina, Natalia, Iwakura, Nobuhiro, Kaji, Hideko, Kaji, Akira

“…Ribosome recycling, the last step in translation, is now accepted as an essential process for prokaryotes. In 2005, three laboratories showed that…”
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Inhibition of Antiassociation Activity of Translation Initiation Factor 3 by Paromomycin by HIROKAWA, Go, KAJI, Hideko, KAJI, Akira

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Orientation of Ribosome Recycling Factor in the Ribosome from Directed Hydroxyl Radical Probing by Lancaster, Laura, Kiel, Michael C., Kaji, Akira, Noller, Harry F.

“…Ribosome recycling factor (RRF) disassembles posttermination complexes in conjunction with elongation factor EF-G, liberating ribosomes for further rounds of…”
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Progression of the Ribosome Recycling Factor through the Ribosome Dissociates the Two Ribosomal Subunits by Barat, Chandana, Datta, Partha P., Raj, V. Samuel, Sharma, Manjuli R., Kaji, Hideko, Kaji, Akira, Agrawal, Rajendra K.

“…After the termination step of translation, the posttermination complex (PoTC), composed of the ribosome, mRNA, and a deacylated tRNA, is processed by the…”
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Correlated Measurement of Endogenous ATE1 Activity on Native Acceptor Proteins in Tissues and Cultured Cells to Detect Cellular Aging by Kaji, Hideko, Kaji, Akira

“…Following our early discovery of arginylation in 1963, we have performed several studies to correlate its activity with essential biological processes. We…”
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Recollection of How We Came Across the Protein Modification with Amino Acids by Aminoacyl tRNA-Protein Transferase by Kaji, Hideko, Kaji, Akira

“…Protein arginylation has been discovered in 1963 as a soluble activity in cell extracts that mediates the addition of amino acids to proteins. This discovery…”
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Inhibition of cell transformation by resveratrol and its derivatives: differential effects and mechanisms involved by SHE, Qing-Bai, MA, Wei-Ya, MINGFU WANG, KAJI, Akira, HO, Chi-Tang, ZIGANG DONG

“…Resveratrol, a constituent of grapes and other foods, has been reported to be a potential cancer chemopreventive agent. Our previous study showed that the…”
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Inhibitory Mechanisms of Tea Polyphenols on the Ultraviolet B-activated Phosphatidylinositol 3-Kinase-dependent Pathway by Nomura, Masaaki, Kaji, Akira, He, Zhiwei, Ma, Wei-Ya, Miyamoto, Ken-ichi, Yang, Chung S., Dong, Zigang

“…In this study, we investigated the effect of tea polyphenols, (−)-epigallocatechin-3-gallate or theaflavins, on UVB-induced phosphatidylinositol 3-kinase…”
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Requirement of ATM in UVA-induced Signaling and Apoptosis by Zhang, Yiguo, Ma, Wei-Ya, Kaji, Akira, Bode, Ann M., Dong, Zigang

“…Solar UVA, but not UVC, reaches the earth's surface and therefore is an important etiological factor for the induction of human skin cancer. ATM kinase is an…”
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A novel function for eukaryotic elongation factor 3: Inhibition of stop codon readthrough in yeast by Kobayashi, Soushi, Kaji, Akira, Kaji, Hideko

“…Eukaryotic elongation factor 3 (eEF3) is one of the essential yeast ribosome-associated ATP-binding cassette type F (ABCF) ATPases. Previously, we found that…”
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Release of Ribosome-bound Ribosome Recycling Factor by Elongation Factor G by Kiel, Michael C, Raj, V Samuel, Kaji, Hideko, Kaji, Akira

“…Elongation factor G (EF-G) and ribosome recycling factor (RRF) disassemble post-termination complexes of ribosome, mRNA, and tRNA. RRF forms stable complexes…”
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