Search Results - "KAJA, Aparna"

Multiplexed transposon-mediated stable gene transfer in human cells by Kahlig, Kristopher M, Saridey, Sai K, Kaja, Aparna, Daniels, Melissa A, George, Alfred L. Jr, Wilson, Matthew H

“…Generation of cultured human cells stably expressing one or more recombinant gene sequences is a widely used approach in biomedical research, biotechnology,…”
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PiggyBac Transposon-based Inducible Gene Expression In Vivo After Somatic Cell Gene Transfer by Saridey, Sai K, Liu, Li, Doherty, Joseph E, Kaja, Aparna, Galvan, Daniel L, Fletcher, Bradley S, Wilson, Matthew H

“…Somatic cell gene transfer has permitted inducible gene expression in vivo through coinfection of multiple viruses. We hypothesized that the highly efficient…”
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Comparative analysis of the recently discovered hAT transposon TcBuster in human cells by Woodard, Lauren E, Li, Xianghong, Malani, Nirav, Kaja, Aparna, Hice, Robert H, Atkinson, Peter W, Bushman, Frederic D, Craig, Nancy L, Wilson, Matthew H

“…Transposons are useful tools for creating transgenic organisms, insertional mutagenesis, and genome engineering. TcBuster, a novel hAT-family transposon system…”
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Temporal self-regulation of transposition through host-independent transposase rodlet formation by Woodard, Lauren E, Downes, Laura M, Lee, Yi-Chien, Kaja, Aparna, Terefe, Eyuel S, Wilson, Matthew H

“…Transposons are highly abundant in eukaryotic genomes, but their mobilization must be finely tuned to maintain host organism fitness and allow for transposon…”
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Genome-wide Mapping of PiggyBac Transposon Integrations in Primary Human T Cells by GALVAN, Daniel L, NAKAZAWA, Yozo, KAJA, Aparna, KETTLUN, Claudia, COOPER, Laurence J. N, ROONEY, Cliona M, WILSON, Matthew H

“…The piggyBac transposon system represents a promising nonviral tool for gene delivery and discovery, and may also be of value for clinical gene therapy…”
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Manipulating piggyBac Transposon Chromosomal Integration Site Selection in Human Cells by Kettlun, Claudia, Galvan, Daniel L, George Jr, Alfred L, Kaja, Aparna, Wilson, Matthew H

“…The ability to direct gene delivery to a user-defined chromosomal location would greatly improve gene transfer applications. The piggyBac transposon system is…”
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Stable Expression of Brain Sodium Channels in Human Cells by Multiplexed Transposon-Mediated Gene Transfer by Kahlig, Kris M., Saridey, Sai, Kaja, Aparna, Daniels, Melissa A., George, Alfred L., Wilson, Matthew H.

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