Search Results - "KAHLER, K"
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Short-term improvement of mental health after a COVID-19 vaccination
Published in PloS one (15-02-2023)“…The role of COVID-19 vaccination on the mental health of the general population remains poorly understood. This study aims to assess the short-term change in…”
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Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia
Published in Nature communications (15-04-2020)“…Despite considerable progress in schizophrenia genetics, most findings have been for large rare structural variants and common variants in well-imputed regions…”
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Genes implicated by a methylome-wide schizophrenia study in neonatal blood show differential expression in adult brain samples
Published in Molecular psychiatry (01-05-2023)“…Schizophrenia is a disabling disorder involving genetic predisposition in combination with environmental influences that likely act via dynamic alterations of…”
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Mental health indicators in Sweden over a 12-month period during the COVID-19 pandemic – Baseline data of the Omtanke2020 Study
Published in Journal of affective disorders (01-02-2023)“…The ongoing COVID-19 pandemic has had an unprecedented impact on the lives of people globally and is expected to have profound effects on mental health. Here…”
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Unravelling the link between sleep and mental health during the COVID-19 pandemic
Published in Stress and health (01-10-2023)“…The emergence of COVID-19 brought unparalleled changes in people's lifestyle, including sleep. We aimed to assess the bidirectional association between sleep…”
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Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach
Published in The Lancet. Psychiatry (01-04-2016)“…Summary Background Therapeutic treatments for schizophrenia do not alleviate symptoms for all patients and efficacy is limited by common, often severe,…”
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Genetics of response to cognitive behavior therapy in adults with major depression: a preliminary report
Published in Molecular psychiatry (01-04-2019)“…Major depressive disorder is heritable and a leading cause of disability. Cognitive behavior therapy is an effective treatment for major depression. By…”
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Genetic Variants in the 9p21.3 Locus Associated with Glioma Risk in Children, Adolescents, and Young Adults: A Case-Control Study
Published in Cancer epidemiology, biomarkers & prevention (01-07-2019)“…Genome-wide association studies have identified germline genetic variants in 25 genetic loci that increase the risk of developing glioma in adulthood. It is…”
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Differential influence of vemurafenib and dabrafenib on patients’ lymphocytes despite similar clinical efficacy in melanoma
Published in Annals of oncology (01-03-2014)“…Since the majority of melanomas eventually become resistant and progress, combining selective BRAF inhibitors (BRAFi) with immunotherapies has been proposed to…”
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Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (05-10-2008)“…Several lines of evidence support the theory of schizophrenia (SZ) being a neurodevelopmental disorder. The structural, cytoarchitectural and functional brain…”
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Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
Published in Journal of psychiatric research (01-09-2010)“…Abstract We have performed a genome-wide association study (GWAS) of schizophrenia in a Norwegian discovery sample of 201 cases and 305 controls (TOP study)…”
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Common-variant associations with fragile X syndrome
Published in Molecular psychiatry (01-03-2019)“…Fragile X syndrome is rare but a prominent cause of intellectual disability. It is usually caused by a de novo mutation that occurs on multiple haplotypes and…”
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Comparison of amlodipine/valsartan/hydrochlorothiazide single pill combination and free combination: adherence, persistence, healthcare utilization and costs
Published in Current medical research and opinion (02-12-2015)“…Objectives: To determine whether amlodipine/valsartan/hydrochlorothiazide single pill combination (SPC) is associated with improved persistence, adherence and…”
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Comprehensive analysis of copy number variation in monozygotic twins discordant for bipolar disorder or schizophrenia
Published in Schizophrenia research (01-05-2013)“…Abstract Copy number variation plays a clear role in the etiology of many psychiatric disorders, particularly schizophrenia. We performed array-CGH to look for…”
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Evidence for a possible association of neurotrophin receptor ( NTRK-3 ) gene polymorphisms with hippocampal function and schizophrenia
Published in Neurobiology of disease (01-06-2009)“…Abstract Altered neurodevelopment and plasticity are implicated in schizophrenia pathology. Based on the important role of neurotrophic factors in brain…”
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Patients with irritable bowel syndrome or constipation have an increased risk for ischaemic colitis
Published in Alimentary pharmacology & therapeutics (15-03-2007)“…Summary Aims To estimate the relative risk for ischaemic colitis in patients with and without irritable bowel syndrome or constipation, and to evaluate the…”
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Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
Published in The New England journal of medicine (25-12-2014)“…In this study, clonal hematopoiesis with somatic mutations was found in 10% of otherwise healthy people older than 65. The risk of hematologic cancer was…”
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Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01-09-2012)“…Disrupted‐in‐Schizophrenia‐1 (DISC1) has been suggested as a susceptibility locus for a broad spectrum of psychiatric disorders. Risk variants have been…”
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Correction: Common-variant associations with fragile X syndrome
Published in Molecular psychiatry (01-12-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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