Search Results - "KAHANE, Philippe"
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Temporal plus epilepsy is a major determinant of temporal lobe surgery failures
Published in Brain (London, England : 1878) (01-02-2016)“…Reasons for failed temporal lobe epilepsy surgery remain unclear. Temporal plus epilepsy, characterized by a primary temporal lobe epileptogenic zone extending…”
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Seizures induced by direct electrical cortical stimulation – Mechanisms and clinical considerations
Published in Clinical neurophysiology (01-01-2016)“…Highlights • CS-induced seizures are used to define the epileptogenic zone in some centres. • Other centres consider them as a by-product of CS with limited…”
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Atlas of the normal intracranial electroencephalogram: neurophysiological awake activity in different cortical areas
Published in Brain (London, England : 1878) (01-04-2018)“…The normal physiological intracranial EEG has not been fully characterised. Frauscher et al. develop a 3D atlas that describes the normal intracranial EEG…”
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High‐Frequency Oscillations in the Normal Human Brain
Published in Annals of neurology (01-09-2018)“…Objective High‐frequency oscillations (HFOs) are a promising biomarker for the epileptogenic zone. It has not been possible, however, to differentiate…”
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High‐frequency oscillations: The state of clinical research
Published in Epilepsia (Copenhagen) (01-08-2017)“…Summary Modern electroencephalographic (EEG) technology contributed to the appreciation that the EEG signal outside the classical Berger frequency band…”
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Four core properties of the human brain valuation system demonstrated in intracranial signals
Published in Nature neuroscience (01-05-2020)“…Estimating the value of alternative options is a key process in decision-making. Human functional magnetic resonance imaging and monkey electrophysiology…”
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Temporal lobe epilepsy and hippocampal sclerosis: Lessons from depth EEG recordings
Published in Epilepsia (Copenhagen) (01-02-2010)Get full text
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How the Human Brain Sleeps: Direct Cortical Recordings of Normal Brain Activity
Published in Annals of neurology (01-02-2020)“…Objective Regional variations in oscillatory activity during human sleep remain unknown. Using the unique ability of intracranial electroencephalography to…”
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Anatomofunctional organization of the insular cortex: A study using intracerebral electrical stimulation in epileptic patients
Published in Epilepsia (Copenhagen) (01-11-2010)“…Summary Purpose: Different lines of evidence suggest that the insular cortex has many important functional roles. Direct electrical stimulation (ES) of the…”
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Optimal level of human intracranial theta activity for behavioral switching in the subthalamo-medio-prefrontal circuit
Published in Nature communications (07-09-2024)“…The ability to switch between rules associating stimuli and responses depend on a circuit including the dorsomedial prefrontal cortex (dmPFC) and the…”
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Direct stimulation of anterior insula and ventromedial prefrontal cortex disrupts economic choices
Published in Nature communications (29-08-2024)“…Neural activity within the ventromedial prefrontal cortex (vmPFC) and anterior insula (aIns) is often associated with economic choices and confidence. However,…”
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Hypothalamic hamartoma: Epileptogenesis beyond the lesion?
Published in Epilepsia (Copenhagen) (01-06-2017)“…Summary The discovery of intrinsic epileptogenicity of the hypothalamic hamartoma (HH) marked a new area in understanding the associated clinical syndrome,…”
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Probabilistic functional tractography of the human cortex revisited
Published in NeuroImage (Orlando, Fla.) (01-11-2018)“…In patients with pharmaco-resistant focal epilepsies investigated with intracranial electroencephalography (iEEG), direct electrical stimulations of a cortical…”
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Diagnostic methods and treatment options for focal cortical dysplasia
Published in Epilepsia (Copenhagen) (01-11-2015)“…Summary Our inability to adequately treat many patients with refractory epilepsy caused by focal cortical dysplasia (FCD), surgical inaccessibility and…”
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Radiofrequency thermocoagulation of the seizure‐onset zone during stereoelectroencephalography
Published in Epilepsia (Copenhagen) (01-03-2017)“…Summary Objective To assess long‐term outcome and identify prognostic factors of radiofrequency thermocoagulation (RFTC) following stereoelectroencephalography…”
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Surgery for Nontumoral Insular Epilepsy Explored by Stereoelectroencephalography
Published in Neurosurgery (01-10-2016)“…Abstract BACKGROUND Hidden by the perisylvian operculi, insular cortex has long been underexplored in the context of epilepsy surgery. Recent studies advocated…”
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Data-driven normative values based on generative manifold learning for quantitative MRI
Published in Scientific reports (30-03-2024)“…In medicine, abnormalities in quantitative metrics such as the volume reduction of one brain region of an individual versus a control group are often provided…”
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Seizure semiology: ILAE glossary of terms and their significance
Published in Epileptic disorders (01-06-2022)“…This educational topical review and Task Force report aims to address learning objectives of the International League Against Epilepsy (ILAE) curriculum. We…”
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Cross-frequency coupling in cortico-hippocampal networks supports the maintenance of sequential auditory information in short-term memory
Published in PLoS biology (05-03-2024)“…It has been suggested that cross-frequency coupling in cortico-hippocampal networks enables the maintenance of multiple visuo-spatial items in working memory…”
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A spatial perturbation framework to validate implantation of the epileptogenic zone
Published in Nature communications (19-06-2024)“…Stereo-electroencephalography (SEEG) is the gold standard to delineate surgical targets in focal drug-resistant epilepsy. SEEG uses electrodes placed directly…”
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