Search Results - "KACEW, S"

A perspective on In vitro developmental neurotoxicity test assay results: An expert panel review by Juberg, D.R., Fox, D.A., Forcelli, P.A., Kacew, S., Lipscomb, J.C., Saghir, S.A., Sherwin, C.M., Koenig, C.M., Hays, S.M., Kirman, C.R.

“…For decades, there has been increasing concern about the potential developmental neurotoxicity (DNT) associated with chemicals. Regulatory agencies have…”
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Prevalence and antifungal susceptibility of Candida parapsilosis complex isolates collected from oral cavities of HIV-infected individuals by MORIS, D. V, MELHEM, M. S. C, MARTINS, M. A, SOUZA, L. R, KACEW, S, SZESZS, M. W, CARVALHO, L. R, PIMENTA-RODRIGUES, M. V, BERGHS, H. A. M, MENDES, R. P

“…At present, few data are available on the prevalence and antifungal susceptibility of Candida parapsilosis complex isolates from HIV-infected individuals. The…”
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An evaluation of possible mechanisms underlying amiodarone-induced pulmonary toxicity by Reasor, M J, Kacew, S

“…The effectiveness of amiodarone in the treatment of cardiac arrhythmias is limited due to the development of pulmonary toxicity. Although the biochemical and…”
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Neurobehavioral alterations in rats exposed to acrylonitrile in drinking water by Rongzhu, L, Suhua, W, Guangwei, X, Fangan, H, Ziqiang, C, Fusheng, J, Kacew, S

“…This study was carried out on rodents, to explore the neurobehavioral effects of acrylonitrile (AN) administered in drinking water. Thirty, male,…”
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Current issues in lactation: advantages, environment, silicone by Kacew, S

“…The physiological process of breast-feeding should be encouraged under most circumstances despite the presence of trace amounts of environmental toxins. The…”
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Inhibition of gentamicin-induced nephrotoxicity by pyridoxal-5'-phosphate in the rat by Kacew, S

“…Daily s.c. injection of gentamicin at either 100 mg/kg for 4 days or 60 mg/kg for 2 weeks produced nephrotoxicity in the adult rat as judged by an increase in…”
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Recent developments in benzene risk assessment by Kacew, S, Lemaire, I

“…An overview is provided of recent developments in benzene risk assessment. Considered are leukemogenic mechanisms of benzene exposure, genotoxicity, enzymatic…”
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Cationic amphiphilic drug-induced renal cortical lysosomal phospholipidosis: an in vivo comparative study with gentamicin and chlorphentermine by Kacew, S

“…Daily subcutaneous injection of gentamicin (100 mg/kg) for 2 days produced a significant decrease in the activities of alkaline phosphatase, a brush-border…”
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Strain as a determinant factor in the differential responsiveness of rats to chemicals by Kacew, S, Ruben, Z, McConnell, R F

“…The beneficial effects derived from the use of chemicals in agriculture, energy production, transportation, pharmaceuticals, and other products that improve…”
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Detoxifying effect of pyridoxine on acetaminophen-induced hepatotoxicity via suppressing oxidative stress injury by Roh, Taehyun, De, Umasankar, Lim, Seong Kwang, Kim, Min Kook, Choi, Seul Min, Lim, Duck Soo, Yoon, Sungpil, Kacew, Sam, Kim, Hyung Sik, Lee, Byung-Mu

“…The detoxifying effect of pyridoxine against acetaminophen (APAP)-induced hepatotoxicity was investigated. HepG2 cells were co-treated with APAP and pyridoxine…”
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CONCLUSIONS, RESEARCH NEEDS, AND RECOMMENDATIONS OF THE EXPERT PANEL: TECHNICAL WORKSHOP ON HUMAN MILK SURVEILLANCE AND RESEARCH FOR ENVIRONMENTAL CHEMICALS IN THE UNITED STATES by Jr, Cheston M. Berlin, LaKind, Judy S., Sonawane, Babasaheb R., Kacew, Sam, Borgert, Christopher J., Bates, Michael N., Birnbach, Nettie, Campbell, Robert, Dermer, Alicia, Dewey, Kathryn G., Ellerbee, Susan M., Fürst, Peter, Giacoia, George P., Gartner, Lawrence, Groer, Maureen, Haynes, Suzanne G., Humerick, Sharron S., Lawrence, Ruth A., Lorber, Matthew, Lovelady, Cheryl, Mason, Ann, Needham, Larry L., Picciano, Mary Frances, Plautz, James, Ryan, John Jake, Selevan, Sherry G., Sumaya, Ciro V., Tully, Mary Rose, Uhl, Kathleen, Vesell, Elliot, Wilson, John T.

“…The conclusions reached by the expert panel convened for the Technical Workshop on Human Milk Surveillance and Research for Environmental Chemicals in the…”
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Diet and rat strain as factors in nervous system function and influence of confounders by Kacew, S, Dixit, R, Ruben, Z

“…The necessity for understanding normal human cognitive processes and behavior, and the mechanisms which result in dysfunction in these processes are dependent…”
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Drug-induced phospholipidosis: are there functional consequences? by Reasor, M J, Kacew, S

“…Phospholipidosis induced by drugs with a cationic amphiphilic structure is a generalized condition in humans and animals that is characterized by an…”
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Gentamicin or chlorphentermine induction of phospholipidosis in the developing organism: role of tissue and species in manifestation of toxicity by Kacew, S

“…Daily, s.c. injection of gentamicin (100 mg/kg) for 2 days produced a significant increase in total phospholipid content of newborn rat kidney. Separation of…”
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Bioavailability of bound pesticide residues and potential toxicologic consequences - an update by Kacew, S, Akhtar, M H, Khan, S U

“…The growing demand for enhanced food productivity to meet the needs of the global population has led farmers to use sophisticated agricultural technology in…”
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Alterations in newborn and adult rat lung morphology and phospholipid levels after chlorcyclizine or chlorphentermine treatment by Kacew, S

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Biological relevance and consequences of chemical- or metal-induced DNA cross-linking by Paustenbach, D J, Finley, B L, Kacew, S

“…A vast number of chemicals are known to induce mutagenesis and/or carcinogenesis in mammals. Although disruption of cellular nuclear material resulting…”
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Inability of nitrendipine to protect against gentamicin nephrotoxicity in the rat by Kacew, S

“…Daily sc injection of gentamicin (100 mg/kg) for 4 days produced a significant decrease in the activities of renal cortical Na+,K+-ATPase and alkaline…”
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Cationic Lipophilic Drugs: Mechanisms of Action, Potential Consequences, and Reversibility by Kacew, S., Reasor, M. J., Ruben, Z.

“…The phenomenon of intralysosomal storage and concentric lamellar bodies formation can be induced by numerous amphiphilic compounds and this has been the…”
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Amiodarone pulmonary toxicity: morphologic and biochemical features by Reasor, M J, Kacew, S

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