Search Results - "KAANDERS, Johannes H"
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Machine learning algorithms for outcome prediction in (chemo)radiotherapy: An empirical comparison of classifiers
Published in Medical physics (Lancaster) (01-07-2018)“…Purpose Machine learning classification algorithms (classifiers) for prediction of treatment response are becoming more popular in radiotherapy literature…”
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A 26-Gene Hypoxia Signature Predicts Benefit from Hypoxia-Modifying Therapy in Laryngeal Cancer but Not Bladder Cancer
Published in Clinical cancer research (01-09-2013)“…Tumor hypoxia is associated with a poor prognosis, hypoxia modification improves outcome, and hypoxic status predicts benefit from treatment. Yet, there is no…”
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Accelerated Radiotherapy With Carbogen and Nicotinamide for Laryngeal Cancer: Results of a Phase III Randomized Trial
Published in Journal of clinical oncology (20-05-2012)“…To report the results from a randomized trial comparing accelerated radiotherapy (AR) with accelerated radiotherapy plus carbogen inhalation and nicotinamide…”
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Head and neck cancer: high-end technology is no guarantee of high-quality care
Published in The Lancet (British edition) (04-06-2022)Get full text
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Hypofractionation vs Conventional Radiation Therapy for Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Matched-Cohort Analysis
Published in International journal of radiation oncology, biology, physics (01-02-2013)“…Purpose Despite conventional radiation therapy, 54 Gy in single doses of 1.8 Gy (54/1.8 Gy) over 6 weeks, most children with diffuse intrinsic pontine glioma…”
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Outcome and toxicity profile after brachytherapy for squamous cell carcinoma of the nasal vestibule
Published in Head & neck (01-09-2015)“…Background The purpose of this study was to evaluate outcome and toxicity profile after primary brachytherapy for squamous cell carcinoma of the nasal…”
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Improving chemoradiation efficacy by PI3-K/AKT inhibition
Published in Cancer treatment reviews (01-12-2014)“…Highlights • Hypoxia is an inherent negative factor for outcome after chemo- and radio-therapy. • PI3-K/AKT signaling affects hypoxia via HIF-1-dependent &…”
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Assessing radiation-induced carotid vasculopathy using ultrasound after unilateral irradiation: a cross-sectional study
Published in Radiation oncology (London, England) (23-07-2022)“…Abstract Background Increased head and neck cancer (HNC) survival requires attention to long-term treatment sequelae. Irradiated HNC survivors have a higher…”
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Long-term cognitive, psychosocial, and neurovascular complications of unilateral head and neck irradiation in young to middle-aged adults
Published in BMC cancer (05-03-2022)“…With a growing, younger population of head and neck cancer survivors, attention to long-term side-effects of prior, often radiotherapeutic, treatment is…”
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CD44 Expression Predicts Local Recurrence after Radiotherapy in Larynx Cancer
Published in Clinical cancer research (01-11-2010)“…To find molecular markers from expression profiling data to predict recurrence of laryngeal cancer after radiotherapy. We generated gene expression data on…”
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Quantitative and clinical implications of the EARL2 versus EARL1 [18F]FDG PET-CT performance standards in head and neck squamous cell carcinoma
Published in EJNMMI research (25-10-2023)“…Background The EANM Research Ltd. (EARL) guidelines give recommendations for harmonization of [ 18 F]FDG PET-CT image acquisition and reconstruction, aiming to…”
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Can FDG PET predict radiation treatment outcome in head and neck cancer? Results of a prospective study
Published in European journal of nuclear medicine and molecular imaging (01-08-2011)“…Purpose In head and neck cancer (HNC) various treatment strategies have been developed to improve outcome, but selecting patients for these intensified…”
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Dynamics of Tumor Hypoxia Measured with Bioreductive Hypoxic Cell Markers
Published in Radiation research (01-02-2007)“…Ljungkvist, A. S. E., Bussink, J., Kaanders, J. H. A. M. and van der Kogel, A. J. Dynamics of Tumor Hypoxia Measured with Bioreductive Hypoxic Cell Markers…”
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An Endorectal Balloon Reduces Intrafraction Prostate Motion During Radiotherapy
Published in International journal of radiation oncology, biology, physics (01-06-2012)“…Purpose To investigate the effect of endorectal balloons (ERBs) on intrafraction and interfraction prostate motion during radiotherapy. Methods and Materials…”
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Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck
Published in BMC cancer (10-10-2012)“…Only a minority of cancer patients benefits from the combination of EGFR-inhibition and radiotherapy in head and neck squamous cell carcinoma (HNSCC). A…”
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Comparison of the effect of individual dietary counselling and of standard nutritional care on weight loss in patients with head and neck cancer undergoing radiotherapy
Published in British journal of nutrition (28-09-2010)“…Clinical research shows that nutritional intervention is necessary to prevent malnutrition in head and neck cancer patients undergoing radiotherapy. The…”
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Differences in metabolism between adeno- and squamous cell non-small cell lung carcinomas: Spatial distribution and prognostic value of GLUT1 and MCT4
Published in Lung cancer (Amsterdam, Netherlands) (01-06-2012)“…Abstract Background Hypoxia leads to changes in tumor cell metabolism such as increased glycolysis. In this study, we examined the spatial distribution of the…”
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Outcome and Prognostic Factors in Olfactory Neuroblastoma: A Rare Cancer Network Study
Published in International journal of radiation oncology, biology, physics (15-11-2010)“…Purpose To assess the outcome in patients with olfactory neuroblastoma (ONB). Methods and Materials Seventy-seven patients treated for nonmetastatic ONB…”
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Diagnostic test accuracy of sentinel lymph node biopsy in squamous cell carcinoma of the oropharynx, larynx, and hypopharynx: A systematic review and meta‐analysis
Published in Head & neck (01-11-2022)“…The aim of this meta‐analysis was to determine the diagnostic test accuracy of sentinel lymph node biopsy (SLNB) in patients with oropharyngeal, laryngeal, and…”
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PET-CT for radiotherapy treatment planning and response monitoring in solid tumors
Published in Nature reviews. Clinical oncology (01-04-2011)“…PET–CT is important for the staging of disease, but also in detecting mechanisms of resistance at the molecular level. In combination with tracers, these…”
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