Search Results - "K Sean Kimbro"

COVID-19 vaccine hesitancy in underserved communities of North Carolina by Doherty, Irene A, Pilkington, William, Brown, Laurin, Billings, Victoria, Hoffler, Undi, Paulin, Lisa, Kimbro, K Sean, Baker, Brittany, Zhang, Tianduo, Locklear, Tracie, Robinson, Seronda, Kumar, Deepak

“…In the United States, underserved communities including Blacks and Latinx are disproportionately affected by COVID-19. This study sought to estimate the…”
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The G-Protein-Coupled Estrogen Receptor Selective Agonist G-1 Attenuates Cell Viability and Migration in High-Grade Serous Ovarian Cancer Cell Lines by Hanafi, Donia, Onyenwoke, Rob U, Kimbro, K Sean

“…The G-protein-coupled estrogen receptor (GPER; G-protein-coupled estrogen receptor 30, also known as GPR30) is a novel estrogen receptor and has emerged as a…”
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Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells by Graham, Tisheeka R, Zhau, Haiyen E, Odero-Marah, Valerie A, Osunkoya, Adeboye O, Kimbro, K Sean, Tighiouart, Mourad, Liu, Tongrui, Simons, Jonathan W, O'Regan, Ruth M

“…The epithelial-to-mesenchymal transition (EMT) is crucial for the migration and invasion of many epithelial tumors, including prostate cancer. Although it is…”
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Population-enriched innate immune variants may identify candidate gene targets at the intersection of cancer and cardio-metabolic disease by Yeyeodu, Susan, Hanafi, Donia, Webb, Kenisha, Laurie, Nikia A, Kimbro, K Sean

“…Both cancer and cardio-metabolic disease disparities exist among specific populations in the US. For example, African Americans experience the highest rates of…”
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Rural Community Engagement for Health Disparities Research: The Unique Role of Historically Black Colleges and Universities (HBCUs) by Taylor, Lorraine C, Watkins, Charity S, Chesterton, Hannah, Kimbro, K Sean, Gerald, Ruby

“…Reducing health disparities in rural communities of color remains a national concern. Efforts to reduce health disparities often center on community…”
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Reciprocal regulation of ZEB1 and AR in triple negative breast cancer cells by Graham, Tisheeka R, Yacoub, Rami, Taliaferro-Smith, LaTonia, Osunkoya, Adeboye O, Odero-Marah, Valerie A, Liu, Tongrui, Kimbro, K. Sean, Sharma, Dipali, O'Regan, Ruth M

“…Zinc-finger enhancer binding protein (ZEB1) is a transcription factor involved in the progression of cancer primarily through promoting epithelial to…”
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1,25-Dihydroxyvitamin D3 Suppresses Prognostic Survival Biomarkers Associated with Cell Cycle and Actin Organization in a Non-Malignant African American Prostate Cell Line by Johnson, Jabril R., Martini, Rachel N., Yuan, Yate-Ching, Woods-Burnham, Leanne, Walker, Mya, Ortiz-Hernandez, Greisha L., Kobeissy, Firas, Galloway, Dorothy, Gaddy, Amani, Oguejiofor, Chidinma, Allen, Blake, Lewis, Deyana, Davis, Melissa B., Kimbro, K. Sean, Yates, Clayton C., Murphy, Adam B., Kittles, Rick A.

“…Vitamin D3 is a steroid hormone that confers anti-tumorigenic properties in prostate cells. Serum vitamin D3 deficiency has been associated with advanced…”
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Toll-like receptor-associated sequence variants and prostate cancer risk among men of African descent by Rogers, E N, Jones, D Z, Kidd, N C, Yeyeodu, S, Brock, G, Ragin, C, Jackson, M, McFarlane-Anderson, N, Tulloch-Reid, M, Sean Kimbro, K, Kidd, L R

“…Recent advances demonstrate a relationship between chronic/recurrent inflammation and prostate cancer (PCA). Among inflammatory regulators, toll-like receptors…”
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COVID-19 vaccine hesitancy in underserved communities of North Carolina by Irene A Doherty, William Pilkington, Laurin Brown, Victoria Billings, Undi Hoffler, Lisa Paulin, K Sean Kimbro, Brittany Baker, Tianduo Zhang, Tracie Locklear, Seronda Robinson, Deepak Kumar

“…BackgroundIn the United States, underserved communities including Blacks and Latinx are disproportionately affected by COVID-19. This study sought to estimate…”
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Aberrant STYK1 expression in ovarian cancer tissues and cell lines by Jackson, Kesmic A, Oprea, Gabriela, Handy, Jeffrey, Kimbro, K Sean

“…Overexpression of STYK1, a putative serine/threonine and tyrosine receptor protein kinase has been shown to confer tumorigenicity and metastatic potential to…”
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Genetic Ancestry Analysis Reveals Misclassification of Commonly Used Cancer Cell Lines by Hooker, Jr, Stanley E, Woods-Burnham, Leanne, Bathina, Madhavi, Lloyd, Stacy, Gorjala, Priyatham, Mitra, Ranjana, Nonn, Larisa, Kimbro, K Sean, Kittles, Rick A

“…Given the scarcity of cell lines from underrepresented populations, it is imperative that genetic ancestry for these cell lines is characterized. Consequences…”
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Contribution of toll-like receptor signaling pathways to breast tumorigenesis and treatment by Kidd, La Creis R, Rogers, Erica N, Yeyeodu, Susan T, Jones, Dominique Z, Kimbro, K Sean

“…Mounting evidence indicates that anomalies in the inflammatory and immune response pathways are essential to tumorigenesis. However, tumor-based innate…”
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Community Engagement Practices at Research Centers in U.S. Minority Institutions: Priority Populations and Innovative Approaches to Advancing Health Disparities Research by Henry Akintobi, Tabia, Sheikhattari, Payam, Shaffer, Emma, Evans, Christina L, Braun, Kathryn L, Sy, Angela U, Mancera, Bibiana, Campa, Adriana, Miller, Stephania T, Sarpong, Daniel, Holliday, Rhonda, Jimenez-Chavez, Julio, Khan, Shafiq, Hinton, Cimona, Sellars-Bates, Kimberly, Ajewole, Veronica, Teufel-Shone, Nicolette I, McMullin, Juliet, Suther, Sandra, Kimbro, K Sean, Taylor, Lorraine, Velez Vega, Carmen M, Williams, Carla, Perry, George, Zuchner, Stephan, Marzan Rodriguez, Melissa, Tchounwou, Paul B

“…This paper details U.S. Research Centers in Minority Institutions (RCMI) Community Engagement Cores (CECs): (1) unique and cross-cutting components, focus…”
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Serum miR-17 levels are downregulated in obese, African American women with elevated HbA1c by Williams, Ariel, Dougal, Dara Mc, Jenkins, Willysha, Greene, Natasha, Williams-DeVane, Clarlynda, Kimbro, K. Sean

“…Purpose Type 2 diabetes is heterogeneous disease characterized by several conditions including hyperglycemia. It is estimated that over 350 million people…”
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Incorporating a New Bioinformatics Component into Genetics at a Historically Black College: Outcomes and Lessons by Holtzclaw, J. David, Eisen, Arri, Whitney, Erika M, Penumetcha, Meera, Hoey, J. Joseph, Kimbro, K. Sean

“…Many students at minority-serving institutions are underexposed to Internet resources such as the human genome project, PubMed, NCBI databases, and other…”
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IRAK4 and TLR3 Sequence Variants may Alter Breast Cancer Risk among African-American Women by Yeyeodu, Susan T, Kidd, Lacreis R, Oprea-Ilies, Gabriela M, Burns, Brian G, Vancleave, Tiva T, Shim, Joong-Youn, Kimbro, K Sean

“…Mounting evidence suggests that imbalances in immune regulation contribute to cell transformation. Women of African descent are an understudied group at high…”
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novel gene STYK1/NOK is upregulated in estrogen receptor-alpha negative estrogen receptor-beta positive breast cancer cells following estrogen treatment by Kimbro, K. Sean, Duschene, Kaitlin, Willard, Margeret, Moore, Jodi-Ann, Freeman, Shalonda

“…The human STYK1/NOK protein is approximately 30-35% similar to mouse fibroblast growth factor receptor 3 and a kinase homologue in D. melanogaster in the…”
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Serum Cytokines are regulated in African Americans with High HbA1c by Kimbro, K Sean, Williams, Ariel

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Sex differences in IL-3, IL-4, and IL-7 correlation with cholesterol and triglyceride levels in African Americans with high HbA1c by Kimbro, K Sean, Wamble, Ezekiel, Williams, Ariel

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Increased circulating cytokine levels in African American women with obesity and elevated HbA1c by Williams, Ariel, Greene, Natasha, Kimbro, K.

“…•Obese African American women express unique population of cytokines.•IL-3, IL-4, IL-7, TNF-α, IFN-α2, & CX3CL1 are differential expressed due to…”
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