Search Results - "K Dimitriadis"
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Wearable blood pressure measurement devices and new approaches in hypertension management: the digital era
Published in Journal of human hypertension (01-11-2022)“…Out-of-office blood pressure (BP) measurement is considered an integral component of the diagnostic algorithm and management of hypertension. In the era of…”
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Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice
Published in Cardiovascular diabetology (26-07-2018)“…Sodium glucose co-transporter2 inhibitors reduce the incidence of cardiovascular events in patients with type 2 diabetes mellitus based on the results of…”
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Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness
Published in Nature communications (22-01-2015)“…In most metazoan nuclei, heterochromatin is located at the nuclear periphery in contact with the nuclear lamina, which provides mechanical stability to the…”
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HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro
Published in Journal of molecular biology (15-05-2024)“…[Display omitted] •Wild-type HIV-1 intasomes are assembled into several distinct multimeric species in vitro. The high-resolution structures of these intasomes…”
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Paraneoplastic endocrine syndromes
Published in Endocrine-related cancer (01-06-2017)“…The majority of neoplasms are responsible for symptoms caused by mass effects to surrounding tissues and/or through the development of metastases. However,…”
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Cell-Cycle-Dependent Structural Transitions in the Human CENP-A Nucleosome In Vivo
Published in Cell (20-07-2012)“…In eukaryotes, DNA is packaged into chromatin by canonical histone proteins. The specialized histone H3 variant CENP-A provides an epigenetic and structural…”
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Robust strategies for automated AFM force curve analysis--I. Non-adhesive indentation of soft, inhomogeneous materials
Published in Journal of biomechanical engineering (01-06-2007)“…The atomic force microscope (AFM) has found wide applicability as a nanoindentation tool to measure local elastic properties of soft materials. An automated…”
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Sulfated endospermic nanocellulose crystals prevent the transmission of SARS-CoV-2 and HIV-1
Published in Scientific reports (28-04-2023)“…Biomaterials with antimicrobial activity are gaining attention due to their biodegradability and efficacy in interacting with a wide range of microorganisms. A…”
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A cytokine panel and procalcitonin in COVID-19, a comparison between intensive care and non-intensive care patients
Published in PloS one (02-05-2022)“…Procalcitonin (PCT) is an acute-phase reactant with concentrations ≥0.5 μg/L indicative of possible bacterial infection in patients with SARS-CoV-2 infection…”
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Empagliflozin improves primary haemodynamic parameters and attenuates the development of atherosclerosis in high fat diet fed APOE knockout mice
Published in Molecular and cellular endocrinology (20-08-2019)“…The effects of long-term treatment with empagliflozin on biochemical and immunohistochemical markers related to atherosclerosis and atherosclerosis development…”
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Biomarkers in marine mussels, Mytilus galloprovincialis, exposed to environmentally relevant levels of the pesticides, chlorpyrifos and penoxsulam
Published in Aquatic toxicology (15-01-2013)“…► Environmental concentrations of two pesticides on mussel physiological status was studied. ► ROS, DNA damage, protein carbonylation and antioxidant capacity…”
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A phage-encoded nucleoid associated protein compacts both host and phage DNA and derepresses H-NS silencing
Published in Nucleic acids research (20-09-2021)“…Abstract Nucleoid Associated Proteins (NAPs) organize the bacterial chromosome within the nucleoid. The interaction of the NAP H-NS with DNA also represses…”
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Introduction of the land snail Eobania vermiculata as a bioindicator organism of terrestrial pollution using a battery of biomarkers
Published in The Science of the total environment (15-02-2011)“…The present study aimed to enrich the group of sentinel organisms of terrestrial pollution biomonitoring, by investigating the efficacy of the land snail…”
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Chemerin induces endothelial cell inflammation: activation of nuclear factor-kappa beta and monocyte-endothelial adhesion
Published in Oncotarget (30-03-2018)“…Chemerin, a chemoattractant protein, acts a G-protein coupled chemokine receptor, Chemokine like Receptor 1/ChemR23; levels of which are elevated in…”
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Spherical indentation of soft matter beyond the Hertzian regime: numerical and experimental validation of hyperelastic models
Published in Biomechanics and modeling in mechanobiology (01-10-2009)“…The lack of practicable nonlinear elastic contact models frequently compels the inappropriate use of Hertzian models in analyzing indentation data and likely…”
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Subendocardial viability ratio as an index of impaired coronary flow reserve in hypertensives without significant coronary artery stenoses
Published in Journal of human hypertension (01-01-2012)“…Subendocardial viability ratio (SEVR), calculated through pulse wave analysis, is an index of myocardial oxygen supply and demand. Our aim was to evaluate the…”
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Determination of Elastic Moduli of Thin Layers of Soft Material Using the Atomic Force Microscope
Published in Biophysical journal (01-05-2002)“…We address three problems that limit the use of the atomic force microscope when measuring elastic moduli of soft materials at microscopic scales. The first…”
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The efficacy of GLP‐1RAs for the management of postprandial hypoglycemia following bariatric surgery: a systematic review
Published in Obesity (Silver Spring, Md.) (01-01-2023)“…Objective Postprandial hyperinsulinemic hypoglycemia with neuroglycopenia is an increasingly recognized complication of Roux‐en‐Y gastric bypass and gastric…”
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Tyrosinase Nanoparticles: Understanding the Melanogenesis Pathway by Isolating the Products of Tyrosinase Enzymatic Reaction
Published in International journal of molecular sciences (13-01-2021)“…Human Tyrosinase (Tyr) is the rate-limiting enzyme of the melanogenesis pathway. Tyr catalyzes the oxidation of the substrate L-DOPA into dopachrome and…”
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Polycystic Ovary Syndrome as a Proinflammatory State: The Role of Adipokines
Published in Current pharmaceutical design (01-01-2016)“…Polycystic Ovary Syndrome (PCOS) is a complex heterogeneous disorder and the most common endocrinopathy amongst women of reproductive age. It is characterized…”
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