Search Results - "Kędzierski, Jacek"
-
1
Remote 1,5-Stereoselectivity Control by an N‑Ligand Switch in the Pd(0)/InI-Promoted Reactions of 4‑Ethynyl-β-lactams with Aldehydes
Published in Organic letters (07-06-2019)“…Configurationally stable ε-amido-propargylindiums, generated in situ from N-Ts-4-ethynylazetidin-2-ones in the presence of InI, catalytic amounts of…”
Get full text
Journal Article -
2
Virtual screening and biological evaluation to identify pharmaceuticals potentially causing hypertension and hypokalemia by inhibiting steroid 11β-hydroxylase
Published in Toxicology and applied pharmacology (15-09-2023)“…Several drugs were found after their market approval to unexpectedly inhibit adrenal 11β-hydroxylase (CYP11B1)-dependent cortisol synthesis. Known side-effects…”
Get full text
Journal Article -
3
Activation of retinoic acid-related orphan receptor γ(t) by parabens and benzophenone UV-filters
Published in Toxicology (Amsterdam) (15-04-2022)“…Retinoic acid-related orphan receptor γt (RORγt) regulates immune responses and its impaired function contributes to inflammatory and autoimmune diseases and…”
Get full text
Journal Article -
4
Assessment of the inhibitory potential of anabolic steroids towards human AKR1D1 by computational methods and in vitro evaluation
Published in Toxicology letters (01-08-2023)“…Exposure to xenobiotics can adversely affect biochemical reactions, including hepatic bile acid synthesis. Bile acids are essential for dissolving lipophilic…”
Get full text
Journal Article -
5
In silico and in vitro assessment of drugs potentially causing adverse effects by inhibiting CYP17A1
Published in Toxicology and applied pharmacology (01-05-2024)“…Cytochrome P450 enzymes (CYPs) play a crucial role in the metabolism and synthesis of various compound classes. While drug-metabolizing CYP enzymes are…”
Get full text
Journal Article -
6
Influence of Catholic School on Development of Education in Poland
Published in Teologia i człowiek (17-06-2019)Get full text
Journal Article -
7
-
8