Search Results - "Küng, Christoph"

Understanding activity-stability tradeoffs in biocatalysts by enzyme proximity sequencing by Vanella, Rosario, Küng, Christoph, Schoepfer, Alexandre A., Doffini, Vanni, Ren, Jin, Nash, Michael A.

“…Understanding the complex relationships between enzyme sequence, folding stability and catalytic activity is crucial for applications in industry and…”
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Shift of Spawning Season and Effects of Climate Warming on Developmental Stages of a Grayling (Salmonidae) by WEDEKIND, CLAUS, KÜNG, CHRISTOPH

“…River-dwelling fish, such as European graylings (Thymallus thymallus), are susceptible to changes in climate because they can often not avoid suboptimal…”
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Zooplankton Feeding Induces Macroscopical Gonad Malformations in Whitefish (Coregonus ssp.) from Lake Thun, Switzerland by Bernet, Daniel, Wahli, Thomas, Küng, Christoph, Segner, Helmut

“…Alterations in gonad morphology are widespread in wild fish populations. Whitefish (Coregonus spp.) from Lake Thun, Switzerland, display a high prevalence of…”
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Different Mechanisms of Endothelial Dysfunction With Aging and Hypertension in Rat Aorta by Kung, Christoph F, Luscher, Thomas F

“…We analyzed the effects and mechanisms of aging in aortic endothelium and vascular smooth muscle of 12-week-old (adult) and 72-week-old (senescent)…”
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Blood Pressure and Vascular Effects of Endothelin Blockade in Chronic Nitric Oxide-Deficient Hypertension by Moreau, Pierre, Takase, Hiroyuki, Kung, Christoph F, Shaw, Sidney, Luscher, Thomas F

“…Because nitric oxide inhibits the synthesis and vasoconstrictor effect of endothelin-1, the effect of endothelin-1 may be enhanced under conditions of chronic…”
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L-NAME Hypertension Alters Endothelial and Smooth Muscle Function in Rat Aorta: Prevention by Trandolapril and Verapamil by Kung, Christoph F, Moreau, Pierre, Takase, Hiroyuki, Luscher, Thomas F

“…Nitric oxide is an important regulator of vascular function and blood pressure. Chronic administration of nitric oxide inhibitors provides a new model of…”
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Gonadal Malformations in Whitefish from Lake Thun: Defining the Case and Evaluating the Role of EDCs by Daniel Bernet, Thomas Wahli, Marc J.-F. Suter, Carlo R. Largiader, Christoph Küng, Sibylle Kipfer, Rik I. L. Eggen, David Bittner, Anja Liedtke, Helmut Segner

“…The objectives of this project were to evaluate i) whether the gonad alterations of whitefish (Coregonus lavaretus spp.) in Lake Thun represent abnormal…”
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Antihypertensive Therapy Prevents Endothelial Dysfunction in Chronic Nitric Oxide Deficiency: Effect of Verapamil and Trandolapril by Takase, Hiroyuki, Moreau, Pierre, Kung, Christoph F, Nava, Eduardo, Luscher, Thomas F

“…The objective of this study was to examine the effects of long-term antihypertensive therapy on blood pressure and vascular responses of resistance arteries…”
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Structure and function of the rat basilar artery during chronic nitric oxide synthase inhibition by Moreau, P, Takase, H, Küng, C F, van Rooijen, M M, Schaffner, T, Lüscher, T F

“…Nitric oxide is an important regulator of vascular tone and may also be implicated in the modulation of vascular growth and structure. This study presents the…”
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Differential effects of the calcium antagonist mibefradil in epicardial and intramyocardial coronary arteries by Küng, C F, Tschudi, M R, Noll, G, Clozel, J P, Lüscher, T F

“…The efficacy of vasodilation depends on the drug and the contractile agonist involved. Furthermore, vasodilation also may be detrimental (i.e., coronary…”
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Different mechanisms of endothelial dysfuction with aging and hypertension in rat aorta by Kung, Christoph F, Luscher, Thomas F

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Chronic blockade of nitric oxide synthase and endothelin receptors during pregnancy in the rat: effect on reactivity of the uterine artery in vitro by Wight, E, Küng, C F, Moreau, P, Takase, H, Lüscher, T F

“…To investigate the effects of chronic blockade of nitric oxide (NO) production and endothelin (ET-1) receptor antagonism on endothelial and vascular smooth…”
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Chronic blockade of nitric oxide-synthase and endothelin receptors during pregnancy in the rat: effect on pregnancy outcome by Wight, E, Küng, C F, Moreau, P, Takase, H, Lüscher, T F

“…To investigate the effects of endothelin-1 (ET-1) receptor antagonism and/or chronic blockade of nitric oxide (NO) production on pregnancy outcome in the rat…”
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