Search Results - "Kühnöl, Caspar"

Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro by Pötschke, Rebecca, Gielen, Gerrit, Pietsch, Torsten, Kramm, Christof, Klusmann, Jan-Henning, Hüttelmaier, Stefan, Kühnöl, Caspar D.

“…Background Glioblastoma (GBM) is the most aggressive form of glioma in adults and children and is associated with very poor prognosis. Pediatric tumors are…”
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Use of nonacog beta pegol during surgery in persons with hemophilia B: a case series by Phua, Chai W., Matino, Davide, Kühnöl, Caspar D., Hegemann, Inga, Matsushita, Tadashi

“…Hemophilia B is a coagulation disorder that puts patients at an increased risk of bleeding. Factor (F) IX replacement therapy is traditionally used in such…”
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Occurrence of high‐grade glioma in Noonan syndrome: Report of two cases by El‐Ayadi, Moatasem, Ansari, Marc, Kühnöl, Caspar D., Bendel, Anne, Sturm, Dominik, Pietsch, Torsten, Kramm, Christof M., Bueren, André O.

“…Noonan syndrome (NS) is an autosomal dominant disorder commonly caused by PTPN11 germline mutations. Patients are characterized by short stature, congenital…”
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MSI1 Promotes the Expression of the GBM Stem Cell Marker CD44 by Impairing miRNA-Dependent Degradation by Pötschke, Rebecca, Haase, Jacob, Glaß, Markus, Simmermacher, Sebastian, Misiak, Claudia, Penalva, Luiz O F, Kühnöl, Caspar D, Hüttelmaier, Stefan

“…The stem cell marker Musashi1 (MSI1) is highly expressed during neurogenesis and in glioblastoma (GBM). MSI1 promotes self-renewal and impairs differentiation…”
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Lenalidomide in an in vitro Dendritic Cell Model for Malignant Gliomas by Kühnöl, Caspar D, Staege, Martin S, Kramm, Christof M

“…Malignant gliomas are tumors with a very unfavorable prognosis. They are characterized by rapid proliferation and invasion in the surrounding healthy tissue…”
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Snail homolog 1 is involved in epithelial-mesenchymal transition-like processes in human glioblastoma cells by Kühnöl, Caspar D, Würfel, Carina, Staege, Martin S, Kramm, Christof

“…Despite advancements in neurosurgery, chemotherapy and radiation therapy, the outcome of patients with glioblastoma remains poor. The migration of tumor cells…”
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The use of Do-Not-Resuscitate-Order equivalents in pediatric palliative care medicine in Germany by Waske, Anja, Kühnöl, Caspar D, Kramm, Christof M

“…In the last years, the structure of Pediatric Palliative Care in Germany has developed more and more. Since 2007, there is a legal claim for a specialized…”
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Immunostimulation by OX40 Ligand Transgenic Ewing Sarcoma Cells by Reuter, Dajana, Staege, Martin S, Kühnöl, Caspar D, Föll, Jürgen

“…Interleukin-2 (IL-2) transgenic Ewing sarcoma cells can induce tumor specific T and NK cell responses and reduce tumor growth in vivo and in vitro…”
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Indoleamine-2,3-dioxygenase in an immunotherapy model for Ewing sarcoma by Max, Daniela, Kühnöl, Caspar D, Burdach, Stefan, Niu, Liguo, Staege, Martin S, Föll, Jürgen L

“…Interleukin-2 (IL2) transgenic Ewing sarcoma cells reduce tumor growth in vivo and in vitro. In the present study we analyzed the expression of immune…”
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Radiotherapy of brain metastases from breast cancer: Treatment results and prognostic factors by KÜHNÖL, JULIA, KÜHNÖL, CASPAR, VORDERMARK, DIRK

“…Brain metastases (BM) from breast cancer are associated with high morbidity and a poor prognosis. The aim of this study was to analyse the role of radiotherapy…”
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RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma by Uren, Philip J., Vo, Dat T., de Araujo, Patricia Rosa, Pötschke, Rebecca, Burns, Suzanne C., Bahrami-Samani, Emad, Qiao, Mei, de Sousa Abreu, Raquel, Nakaya, Helder I., Correa, Bruna R., Kühnöl, Caspar, Ule, Jernej, Martindale, Jennifer L., Abdelmohsen, Kotb, Gorospe, Myriam, Smith, Andrew D., Penalva, Luiz O. F.

“…The conserved RNA-binding protein Musashi1 (MSI1) has emerged as a key oncogenic factor in numerous solid tumors, including glioblastoma. However, its…”
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Using simulated patients to test competency in child protection medicine in the third section of the medical examination by Steglich, Jonas, Hempel, Linn, Jaspers, Susanna, Stoevesandt, Dietrich, Weber, Marko, Kunze, Christian, Weihrauch-Blüher, Susann, Kühnöl, Caspar, Woydt, Lina

“…During the COVID-19 pandemic, the third section of the medical examination could be performed with simulation patients. Simulations enable standardized…”
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EPID-18. NOONAN SYNDROME CAN BE ASSOCIATED WITH HIGH GRADE GLIOMA; A REPORT OF TWO CASES by El-Ayadi, Moatasem, Ansari, Marc, Kühnöl, Caspar, Bendel, Anne, Sturm, Dominik, Pietsch, Torsten, Kramm, Christof, von Bueren, André

“…Noonan syndrome (NS), an autosomal dominant disorder, is characterized by short stature, congenital heart defects, developmental delay, and facial dysmorphism…”
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CD137 stimulation and p38 MAPK inhibition improve reactivity in an in vitro model of glioblastoma immunotherapy by Kühnöl, Caspar, Herbarth, Monique, Föll, Jürgen, Staege, Martin S., Kramm, Christof

“…Dendritic cell vaccination has become an interesting option for cancer immunotherapy. Tumor-lysate-pulsed dendritic cells (DC) can prime naïve T cells and…”
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Einsatz von Simulationspersonen zur Prüfung von Handlungskompetenz im Bereich der Kinderschutzmedizin im Dritten Abschnitt der Ärztlichen Prüfung by Steglich, Jonas, Hempel, Linn, Jaspers, Susanna, Stoevesandt, Dietrich, Weber, Marko, Kunze, Christian, Weihrauch-Blüher, Susann, Kühnöl, Caspar, Woydt, Lina

“…Zusammenfassung In der COVID-19-Pandemie war die Durchführung des Dritten Abschnitts der Ärztlichen Prüfung mit Simulationspersonen möglich. Simulationen…”
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Prognostic Biomarkers for Hodgkin Lymphoma by Staege, Martin S., Kewitz, Stefanie, Bernig, Toralf, Kühnöl, Caspar, Mauz-Körholz, Christine

“…The prognosis of patients with classical Hodgkin lymphoma following chemo- and radiotherapy has been excellent during the last 4 decades. However, the…”
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Use of nonacog beta pegol during surgery in persons with hemophilia B: a case series by Phua, Chai W, Matino, Davide, Kühnöl, Caspar D, Hegemann, Inga, Matsushita, Tadashi

“…BackgroundHemophilia B is a coagulation disorder that puts patients at an increased risk of bleeding. Factor (F) IX replacement therapy is traditionally used…”
Get full text

Immuno-stimulation by OX40 ligand transgenic Ewing sarcoma cells by Dajana eReuter, Martin Sebastian Staege, Caspar David Kühnöl, Juergen eFoell

“…Interleukin-2 (IL-2) transgenic Ewing sarcoma cells can induce tumor specific T and NK cell responses and reduce tumor growth in vivo and in vitro…”
Get full text