Search Results - "Kühn, Joachim E."

Entry of herpes simplex virus type 1 (HSV-1) into the distal axons of trigeminal neurons favors the onset of nonproductive, silent infection by Hafezi, Wali, Lorentzen, Eva U, Eing, Bodo R, Müller, Marcus, King, Nicholas J C, Klupp, Barbara, Mettenleiter, Thomas C, Kühn, Joachim E

“…Following productive, lytic infection in epithelia, herpes simplex virus type 1 (HSV-1) establishes a lifelong latent infection in sensory neurons that is…”
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Broadly Applicable, Virus-Free Dual Reporter Assay to Identify Compounds Interfering with Membrane Fusion: Performance for HSV-1 and SARS-CoV-2 by Classen, Nica, Ulrich, Diana, Hofemeier, Arne, Hennies, Marc Tim, Hafezi, Wali, Pettke, Aleksandra, Romberg, Marie-Luise, Lorentzen, Eva U, Hensel, Andreas, Kühn, Joachim E

“…Membrane fusion constitutes an essential step in the replication cycle of numerous viral pathogens, hence it represents an important druggable target. In the…”
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The genome of HSV-1 translocates through the nuclear pore as a condensed rod-like structure by Shahin, Victor, Hafezi, Wali, Oberleithner, Hans, Ludwig, Yvonne, Windoffer, Barbara, Schillers, Hermann, Kühn, Joachim E

“…Incoming herpes simplex virus type-1 (HSV-1) capsids are known to dock to the nuclear pore complex (NPC) and release their genome. It has remained elusive,…”
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Targeted whole-viral genome sequencing from formalin-fixed paraffin-embedded neuropathology specimens by Gorißen, Charlotte, Albers, Anne, Ruf, Viktoria, Chteinberg, Emil, Siebert, Reiner, Schweizer, Leonille, Kaufmann, Lukas, Kühn, Joachim E., Tappe, Dennis, Kuhlmann, Tanja, Thomas, Christian

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Enhanced viral clearance and reduced leukocyte infiltration in experimental herpes encephalitis after intranasal infection of CXCR3-deficient mice by Zimmermann, J., Hafezi, W., Dockhorn, A., Lorentzen, Eva U., Krauthausen, M., Getts, Daniel R., Müller, M., Kühn, Joachim E., King, Nicholas J. C.

“…Herpes simplex virus type 1 (HSV-1) encephalitis (HSE) is the most common fatal sporadic encephalitis in developed countries. There is evidence from HSE animal…”
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Heparin increases the infectivity of Human Papillomavirus Type 16 independent of cell surface proteoglycans and induces L1 epitope exposure by Cerqueira, Carla, Liu, Yan, Kühling, Lena, Chai, Wengang, Hafezi, Wali, Kuppevelt, Toin H., Kühn, Joachim E., Feizi, Ten, Schelhaas, Mario

“…Summary Human Papillomaviruses (HPVs) are the etiological agents of cervical cancer, and HPV‐16 is the most prevalent type. Several HPVs require heparan…”
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Cutaneous RANK–RANKL Signaling Upregulates CD8-Mediated Antiviral Immunity during Herpes simplex Virus Infection by Preventing Virus-Induced Langerhans Cell Apoptosis by Klenner, Lars, Hafezi, Wali, Clausen, Björn E., Lorentzen, Eva U., Luger, Thomas A., Beissert, Stefan, Kühn, Joachim E., Loser, Karin

“…Herpes simplex virus-type 1 (HSV-1) causes the majority of cutaneous viral infections. Viral infections are controlled by the immune system, and CD8+ cytotoxic…”
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Evaluation of Two Enzyme Immunoassays for Detection of Human Rotaviruses in Fecal Specimens by EING, Bodo R, MAY, Guenter, BAUMEISTER, Horst G, KÜHN, Joachim E

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Exceptional mechanical and structural stability of HSV-1 unveiled with fluid atomic force microscopy by Liashkovich, Ivan, Hafezi, Wali, Kühn, Joachim E, Oberleithner, Hans, Kramer, Armin, Shahin, Victor

“…Evidence is emerging that changes in the structural and mechanical properties of viral particles are closely linked and that such changes are essential to…”
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Reciprocal transmission of herpes simplex virus type 1 (HSV‐1) between corneal epithelium and trigeminal neurites in an embryonic chick organ culture by Hafezi, Wali, Eing, Bodo R., Lorentzen, Eva U., Thanos, Solon, Kühn, Joachim E.

“…ABSTRACT Reciprocal transmission between epithelia and sensory neurons of the peripheral nervous system is a crucial step in the life cycle of herpes simplex…”
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Comparison of two commercially available pp65 antigenemia tests and COBAS Amplicor CMV Monitor for early detection and quantification of episodes of human CMV-viremia in transplant recipients by May, Gunter, Kuhn, Joachim E, Eing, Bodo R

“…The performance of two commercially available CMV pp65 antigenemia (AG) assays (CINA kit, Argene Biosoft, CK, and CMV Brite kit, IQ Products, CBK), and a…”
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Polymerase Chain Reaction (PCR) from Ficoll-Purified Polymorphonuclear Leukocytes for Monitoring Cytomegalovirus Infections in Renal Allograft Recipients: Superior Sensitivity and Similar Specificity Compared with Plasma PCR by Schäfer, Peter, Kühn, Joachim E., Tenschert, Werner, Eing, Bodo, Schröter, Matthias, Laufs, Rainer

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Genital herpes simplex virus type 1 infection: new fields for an old acquaintance? by Lippelt, Lars, Braun, Rüdiger W, Kühn, Joachim E

“…Herpes simplex virus (HSV)-2 is the principal agent of chronic remittent genital herpes. Worldwide, only 10-20% of genital isolates are HSV-1. Studies from the…”
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Heparin increases the infectivity of Human Papillomavirus Type 16 independent of cell surface proteoglycans and induces L1 epitope exposure: Interactions of HPV-16 with GAGs by Cerqueira, Carla, Liu, Yan, Kühling, Lena, Chai, Wengang, Hafezi, Wali, van Kuppevelt, Toin H., Kühn, Joachim E., Feizi, Ten, Schelhaas, Mario

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Replication of herpes simplex virus type 1 in differentiated human promyelocytic HL-60 cells by Pientong, C, Weisshart, K, Kühn, J E, Knopf, C W, Braun, R W

“…The capability of herpes simplex virus type 1 (HSV-1), strain Angelotti (ANG), to replicate in human promyelocytic HL-60 cells treated with…”
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Detection of human serum antibodies against type-specifically reactive peptides from the N-terminus of glycoprotein B of herpes simplex virus type 1 and type 2 by surface plasmon resonance by Wittekindt, Claus, Fleckenstein, Burkhard, Wiesmüller, Karl-Heinz, Eing, Bodo R., Kühn, Joachim E.

“…A single-step surface plasmon resonance protocol for the detection of antibodies against herpes simplex virus type 1 and type 2 (HSV-1, HSV-2) in human sera…”
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In vivo genetic variability of the HIV-1 vif gene by Wieland, U, Hartmann, J, Suhr, H, Salzberger, B, Eggers, H J, Kühn, J E

“…The human immunodeficiency virus type 1 (HIV-1) vif gene encodes a 23-kDa protein (viral infectivity factor) whose exact mechanism of action is not entirely…”
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Diversity of the vif gene of human immunodeficiency virus type 1 in Uganda by Wieland, U, Seelhoff, A, Hofmann, A, Kuhn, JE, Eggers, HJ, Mugyenyi, P, Schwander, S

“…U Wieland, A Seelhoff, A Hofmann, JE Kuhn, HJ Eggers, P Mugyenyi and S Schwander Institut fur Virologie, Universitat zu Koln, Germany…”
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Replication-competent herpes simplex virus type 1 mutant expressing an autofluorescent glycoprotein H fusion protein by Lorentzen, E U, Eing, B R, Hafezi, W, Manservigi, R, Kühn, J E

“…The heterocomplex of glycoproteins H (gH) and L (gL) of herpes simplex virus type 1 (HSV-1) is essential for viral infectivity and is involved in viral…”
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Mapping of linear antigenic determinants on glycoprotein C of herpes simplex virus type 1 and type 2 recognized by human serum immunoglobulin G antibodies by Ackermann, Grit, Ackermann, Frank, Eggers, Hans J., Wieland, Ulrike, Kühn, Joachim E.

“…Using membrane‐based dekapeptides, the reactivity of human serum antibodies with linear antigenic determinants of herpes simplex virus (HSV) type 1 and type 2…”
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