Search Results - "Kühn, A.A"

Automated Optimization of Subcortical Cerebral MR Imaging-Atlas Coregistration for Improved Postoperative Electrode Localization in Deep Brain Stimulation by Schonecker, T, Kupsch, A, Kuhn, A.A, Schneider, G.-H, Hoffmann, K.-T

“…The efficacy of deep brain stimulation in treating movement disorders depends critically on electrode localization, which is conventionally described by using…”
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Randomized double-blind sham-controlled trial of thalamic versus GPi stimulation in patients with severe medically refractory Gilles de la Tourette syndrome by Müller-Vahl, K.R., Szejko, N., Saryyeva, A., Schrader, C., Krueger, D., Horn, A., Kühn, A.A., Krauss, J.K.

“…There are still no sufficient data regarding the use of deep brain stimulation (DBS) in Gilles de la Tourette syndrome (GTS) and no agreement on optimal…”
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EP 33. Prolonged pauses in verbal fluency tasks under active VIM-DBS – Does it delay automatic lexical co-activation? by Ehlen, F, Vonberg, I, Fromm, O, Kühn, A.A, Klostermann, F

“…Background Deep Brain Stimulation (DBS) of the thalamic ventral intermediate nucleus (VIM) is a common therapeutic option for patients with essential tremor…”
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SP 2. Pallidal low frequency activity correlates with dystonic symptoms in patients with cervical dystonia by Neumann, W.-J, Huebl, J, Brücke, C, Slentz, C, Schneider, G.-H, Kühn, A.A

“…Question Low frequency (4–12 Hz) oscillations in the internal pallidum (GPi) have been shown to be correlated and coherent with dystonic EMG activity and have…”
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Neural correlates of lexical decisions in Parkinson’s Disease revealed with multivariate extraction of cortico-subthalamic interactions by Hohlefeld, F.U, Ewald, A, Ehlen, F, Tiedt, H.O, Horn, A, Kühn, A.A, Curio, G, Klostermann, F, Nikulin, V.V

“…Highlights • In Parkinson's disease patients EEG and local field potentials from deep brain stimulation subthalamic electrodes were simultaneously recorded. •…”
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EPV 15. Reward processing modulates beta activity in local field potentials of the subthalamic nucleus by Schroll, H, Horn, A, Runge, J, Schneider, G.-H, Krauss, J.K, Hamker, F.H, Kühn, A.A

“…In Parkinson’s disease, dopamine loss results in an increase in beta oscillations in the subthalamic nucleus that correlates well with the severity of…”
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Correlation between cortical and subcortical neural dynamics on multiple time scales in Parkinson’s disease by Hohlefeld, F.U, Ehlen, F, Tiedt, H.O, Krugel, L.K, Horn, A, Kühn, A.A, Curio, G, Klostermann, F, Nikulin, V.V

“…Graphical abstract Long-range temporal correlations (LRTC, up to 20 s) in the amplitude dynamics of cortical alpha oscillations relate to subcortical…”
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Functional and effective connectivity in subthalamic local field potential recordings of patients with Parkinson’s disease by Hohlefeld, F.U, Huchzermeyer, C, Huebl, J, Schneider, G.-H, Nolte, G, Brücke, C, Schönecker, T, Kühn, A.A, Curio, G, Nikulin, V.V

“…Highlights • Regional connectivity in STN–LFP (10–30 Hz) was not due to volume conduction. • Functional connectivity was increased in the levodopa ON…”
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P177. Relation between cortical and subcortical neural dynamics on multiple time scales in patients with Parkinson’s disease by Hohlefeld, F.U, Ehlen, F, Tiedt, H.O, Krugel, L.K, Horn, A, Kühn, A.A, Curio, G, Klostermann, F, Nikulin, V.V

“…Long-range temporal correlations (LRTC) were frequently demonstrated in the cortically dominant alpha rhythm (8–13 Hz) in healthy subjects and in different…”
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German registry of paediatric deep brain stimulation in patients with childhood-onset dystonia (GEPESTIM) by Koy, A., MD, Weinsheimer, M, Pauls, K.A.M., MD, PhD, Kühn, A.A., MD, Krause, P., MD, Huebl, J., MD, Schneider, G.-H., MD, Deuschl, G., MD, PhD, Erasmi, R., MD, Falk, D., MD, Krauss, J.K., MD, Lütjens, G., MD, Schnitzler, A., MD, Wojtecki, L., MD, Vesper, J., MD, PhD, Korinthenberg, R., MD, Coenen, V.A., MD, Visser-Vandewalle, V., MD, PhD, Hellmich, M., PhD, Timmermann, L., MD

“…Abstract Background Data on paediatric DBS is limited, especially for long-term outcomes, because of small numbers in single center series and lack of…”
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Patterns of abnormal motor cortex excitability in atypical parkinsonian syndromes by Kühn, A.A, Grosse, P, Holtz, K, Brown, P, Meyer, B.-U, Kupsch, A

“…Objective: Multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal-ganglionic degeneration (CBGD) are all clinically…”
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P 47 The Impact of directional deep brain stimulation on subthalamic beta power in Parkinson's disease by Kaplan, J., Busch, J.L., Schneider, G.H., Kühn, A.A.

“…Introduction: Beta power in subthalamic local field potentials (LFPs) is a well established biomarker for bradykinesia-rigidity in idiopathic Parkinson's…”
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P2.037 Activation of the subthalamic nucleus during emotional processing predicts severity of postoperative depressive symptoms in PD-patients by Übl, J.H, Brücke, C, Siegert, S, Schneider, G.-H, Kupsch, A, Yarrow, K, Kühn, A.A

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Valence or arousal related activation of the subthalamic area in emotion processing in Parkinsons disease? by Brücke, C, Kempf, F, Trottenberg, T, Kupsch, A, Kopp, U, Schneider, G.H, Hariz, M, Yarrow, K, Nuttin, B, Brown, P, Kühn, A.A

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P 43 Optimizing beta-burst driven adaptive deep brain stimulation for Parkinson's disease by Busch, J.L., Kaplan, J., Merk, T., Köhler, R., Neumann, W.J., Kühn, A.A.

“…Introduction Adaptive deep brain stimulation (DBS) aims at improving DBS therapy by adjusting stimulation amplitude to patient specific biomarkers tracked in…”
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P 34 StimFit – A data-driven algorithm for automated deep brain stimulation programming by Roediger, J., Dembek, T., Wenzel, G., Butenko, K., Kühn, A.A., Horn, A.

“…Question: Finding the optimal deep brain stimulation (DBS) parameters out of a multitude of possible combinations by trial-and-error is time-consuming and…”
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P 33 Changes in functional connectivity relate to modulation of cognitive control by subthalamic stimulation by Achtzehn, J., Irmen, F., Horn, A., Güttler, C., de Almeida Marcelino, A.L., Wenzel, G., Schneider, G.H., Neumann, W.J., Kühn, A.A.

“…Introduction Using cognitive control,humans can flexibly influence behavior based on setgoals, whichincludes overriding impulses by inhibiting automatic…”
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P 29 Persistent synaptic inhibition of the subthalamic nucleus by high frequency stimulation by Steiner, L.A., Kühn, A.A., Geiger, J., Alle, H., Popovic, M., Kalia, S., Hodaie, M., Lozano, A., Hutchison, W., Milosevic, L.

“…Background: Deep brain stimulation (DBS) provides symptomatic relief in a growing number of neurological indications, but local synaptic dynamics in response…”
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FV 5 Striato-pallidal connectivity in oscillatory activity of patients with dystonia by Lofredi, R., Scheller, U., Feldmann, L., Neumann, W.J., Saryyeva, A., Schneider, G.H., Krauss, J.K., Sander-Thoemnes, T., Kühn, A.A.

“…Introduction: Dystonia is a network disorder in which aberrant signaling maybe associated with an imbalance between direct and indirect pathway activity…”
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P 18 Can connectivity link the effects of STN and VIM DBS across tremor-related diseases? A multi-cohort functional connectivity study by Goede, L.L., Al-Fatly, B., Neudorfer, C., Li, N., Odekerken, V.J.J., de Bie, R.M.A., Reich, M.M., Volkmann, J., Kühn, A.A., Horn, A.

“…Introduction: Tremor is defined as an involuntary, rhythmic oscillatory movement of a body part and represents one of the most common symptoms in movement…”
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