Search Results - "Körner, Sandrina"

Microsatellite instability in pulmonary adenocarcinomas: a comprehensive study of 480 cases by Warth, Arne, Körner, Sandrina, Penzel, Roland, Muley, Thomas, Dienemann, Hendrik, Schirmacher, Peter, von Knebel-Doeberitz, Magnus, Weichert, Wilko, Kloor, Matthias

“…A major molecular pathway of genetic instability in cancer is DNA mismatch repair deficiency, leading to accumulation of numerous mutations at repetitive DNA…”
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High numbers of PDCD1 (PD-1)-positive T cells and B2M mutations in microsatellite-unstable colorectal cancer by Janikovits, Jonas, Müller, Meike, Krzykalla, Julia, Körner, Sandrina, Echterdiek, Fabian, Lahrmann, Bernd, Grabe, Niels, Schneider, Martin, Benner, Axel, Doeberitz, Magnus von Knebel, Kloor, Matthias

“…DNA mismatch repair (MMR)-deficient cancers accumulate high numbers of coding microsatellite mutations, which lead to the generation of highly immunogenic…”
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Effects of Vitamin D on tumor cell proliferation and migration, tumor initiation and anti-tumor immune response in head and neck squamous cell carcinomas by Brust, Lukas A., Linxweiler, Maximilian, Schnatmann, Jana, Kühn, Jan-Philipp, Knebel, Moritz, Braun, Felix L., Wemmert, Silke, Menger, Michael D., Schick, Bernhard, Holick, Michael F., Kuo, Fengshen, Morris, Luc G.T., Körner, Sandrina

“…Head and neck squamous cell carcinomas (HNSCCs) are among the six most common cancers, with a constantly poor prognosis. Vitamin D has been found to have…”
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Prognostic impact of intra- and peritumoral immune cell subpopulations in head and neck squamous cell carcinomas - comprehensive analysis of the TCGA-HNSC cohort and immunohistochemical validation on 101 patients by Knebel, Moritz, Körner, Sandrina, Kühn, Jan Philipp, Wemmert, Silke, Brust, Lukas, Smola, Sigrun, Wagner, Mathias, Bohle, Rainer M, Morris, Luc G T, Pandey, Abhinav, Schick, Bernhard, Linxweiler, Maximilian

“…Due to the expanding role of immune checkpoint inhibition in the treatment of head and neck squamous cell carcinoma, understanding immunological processes in…”
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Antagonizing Sec62 function in intracellular Ca2+ homeostasis represents a novel therapeutic strategy for head and neck cancer by Körner, Sandrina, Pick, Tillman, Bochen, Florian, Wemmert, Silke, Körbel, Christina, Menger, Michael D., Cavalié, Adolfo, Kühn, Jan-Philipp, Schick, Bernhard, Linxweiler, Maximilian

“…Various cancer types including head and neck squamous cell carcinomas (HNSCC) show a frequent amplification of chromosomal region 3q26 that encodes, among…”
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Vitamin D deficiency in head and neck cancer patients - prevalence, prognostic value and impact on immune function by Bochen, Florian, Balensiefer, Benedikt, Körner, Sandrina, Bittenbring, Jörg Thomas, Neumann, Frank, Koch, Armand, Bumm, Klaus, Marx, Anke, Wemmert, Silke, Papaspyrou, Georgios, Zuschlag, David, Kühn, Jan Philipp, Al Kadah, Basel, Schick, Bernhard, Linxweiler, Maximilian

“…Vitamin D deficiency is frequently observed in human cancer patients and a prognostic relevance could be shown for some entities. Additionally, it is known…”
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Podoplanin expression in lymph node metastases of head and neck cancer and cancer of unknown primary patients by Kühn, Jan Philipp, Bochen, Florian, Körner, Sandrina, Schick, Bernhard, Wagner, Mathias, Smola, Sigrun, Berkó-Göttel, Barbara, Morris, Luc G.T., Wang, Jingming, Bozzato, Alessandro, Linxweiler, Maximilian

“…Introduction Head and neck squamous cell carcinomas (HNSCCs) are cancers with generally poor prognosis. Outcomes have not improved in decades, with more than…”
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Augmented reality‐enhanced navigation in endoscopic sinus surgery: A prospective, randomized, controlled clinical trial by Linxweiler, Maximilian, Pillong, Lukas, Kopanja, Dragan, Kühn, Jan P., Wagenpfeil, Stefan, Radosa, Julia C., Wang, Jingming, Morris, Luc G. T., Al Kadah, Basel, Bochen, Florian, Körner, Sandrina, Schick, Bernhard

“…Objective Endoscopic sinus surgery represents the gold standard for surgical treatment of chronic sinus diseases. Thereby, navigation systems can be of…”
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Dual Sec62/Ki67 immunocytochemistry of liquid‐based cytological preparations represents a highly valid biomarker for non‐invasive detection of head and neck squamous cell carcinomas by Kühn, Jan Philipp, Speicher, Stefanie, Linxweiler, Barbara, Körner, Sandrina, Rimbach, Hugo, Wagner, Mathias, Solomayer, Erich Franz, Schick, Bernhard, Linxweiler, Maximilian

“…Background Head and neck squamous cell carcinomas (HNSCC) are frequently diagnosed in advanced stages, which limits therapeutic options and results in…”
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Targeted Therapy in Salivary Gland Cancer: Prevalence of a Selected Panel of Actionable Molecular Alterations in a German Tertiary Referral Center Patient Cohort by Linxweiler, Maximilian, Wemmert, Silke, Braun, Felix Leon, Körner, Sandrina, Brust, Lukas Alexander, Knebel, Moritz, Klamminger, Gilbert Georg, Wagner, Mathias, Morris, Luc G. T., Kühn, Jan Philipp

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Prediction of lymph node status in patients with surgically treated head and neck squamous cell carcinoma via neck lavage cytology: A pilot study by Rimbach, Hugo, Linxweiler, Maximilian, Körner, Sandrina, Smola, Sigrun, Linxweiler, Barbara, Speicher, Stefanie, Helfrich, Johanna, Solomayer, Erich‐Franz, Wagner, Mathias, Schick, Bernhard, Kühn, Jan Philipp

“…Background Neck dissection is a standardized surgical procedure for patients with head and neck squamous cell carcinoma (HNSCC) and plays a critical role in…”
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Cytology-based Cancer Surgery of the Head and Neck (CyCaS-HN): a prospective, randomized, controlled clinical trial by Linxweiler, Maximilian, Körner, Sandrina, Wemmert, Silke, Rimbach, Hugo, Helfrich, Johanna, Linxweiler, Barbara, Takacs, Zoltan Ferenc, Solomayer, Erich Franz, Wagner, Mathias, Morris, Luc G. T., Schick, Bernhard, Kühn, Jan Philipp

“…Purpose Liquid-based cytology (LBC) is routinely used in gynecology but is rarely applied in head and neck oncology though many suspicious lesions are easily…”
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Expression of 3q Oncogene SEC62 Predicts Survival in Head and Neck Squamous Cell Carcinoma Patients Treated with Primary Chemoradiation by Linxweiler, Maximilian, Schneider, Matthias, Körner, Sandrina, Knebel, Moritz, Brust, Lukas Alexander, Braun, Felix Leon, Wemmert, Silke, Wagner, Mathias, Hecht, Markus, Schick, Bernhard, Kühn, Jan Philipp

“…Primary chemoradiotherapy (CRT) is an established treatment option for locally advanced head and neck squamous cell carcinomas (HNSCC) usually combining…”
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HPV Status as Prognostic Biomarker in Head and Neck Cancer-Which Method Fits the Best for Outcome Prediction? by Kühn, Jan Philipp, Schmid, Wendelin, Körner, Sandrina, Bochen, Florian, Wemmert, Silke, Rimbach, Hugo, Smola, Sigrun, Radosa, Julia Caroline, Wagner, Mathias, Morris, Luc G T, Bozzato, Victoria, Bozzato, Alessandro, Schick, Bernhard, Linxweiler, Maximilian

“…The incidence of human papillomavirus (HPV)-related head and neck cancer (HNSCC) is rising globally, presenting challenges for optimized clinical management…”
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Expression of SEC62 Oncogene in Benign, Malignant and Borderline Melanocytic Tumors-Unmasking the Wolf in Sheep's Clothing? by Müller, Cornelia S L, Pföhler, Claudia, Wahl, Maria, Bochen, Florian, Körner, Sandrina, Kühn, Jan Philipp, Bozzato, Alessandro, Schick, Bernhard, Linxweiler, Maximilian

“…oncogene located at chromosomal region 3q26 encodes for a transmembrane protein of the endoplasmic reticulum (ER) and is expressed at high levels in numerous…”
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