Search Results - "Königsberg, Mina"
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Nrf2 signaling and redox homeostasis in the aging heart: A potential target to prevent cardiovascular diseases?
Published in Ageing research reviews (01-03-2016)“…Graphical abstract…”
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The Effect of MPP+ on the Viability of Primary Cortical Astrocytes Isolated from Female and Male Wistar Rats of Different Ages
Published in Cellular and molecular neurobiology (01-03-2019)“…Although age is known to be the main risk for developing chronic and neurodegenerative diseases, those illnesses have a different prevalence depending on the…”
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t-BHQ Protects Against Oxidative Damage and Maintains the Antioxidant Response in Malnourished Rats
Published in Dose-response (01-07-2018)“…Objective: Tert-butylhydroquinone (t-BHQ) protective effect against oxidative damage in thymus from malnourished pops-rats was evaluated. Methods: Malnutrition…”
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Long-Term Moderate Exercise Combined with Metformin Treatment Induces an Hormetic Response That Prevents Strength and Muscle Mass Loss in Old Female Wistar Rats
Published in Oxidative medicine and cellular longevity (2019)“…Sarcopenia is a syndrome characterized by a progressive and generalized skeletal muscle mass and strength loss, as well as a poor physical performance, which…”
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Sensory and memory processing in old female and male Wistar rat brain, and its relationship with the cortical and hippocampal redox state
Published in GeroScience (01-08-2021)“…The brain is one of the most sensitive organs damaged during aging due to its susceptibility to the aging-related oxidative stress. Hence, in this study, the…”
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Oxidative damage and antioxidant defense in thymus of malnourished lactating rats
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-11-2015)“…Abstract Objective Malnutrition has been associated with oxidative damage by altered antioxidant protection mechanisms. Specifically, the aim of this study was…”
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Bik subcellular localization in response to oxidative stress induced by chemotherapy, in Two different breast cancer cell lines and a Non-tumorigenic epithelial cell line
Published in Journal of applied toxicology (01-11-2015)“…Cancer chemotherapy remains one of the preferred therapeutic modalities against malignancies despite its damaging side effects. An expected outcome while…”
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Obesity: Pathophysiology, monosodium glutamate-induced model and anti-obesity medicinal plants
Published in Biomedicine & pharmacotherapy (01-03-2019)“…•MSG-induced model is of value to study the pathophysiology of obesity.•The use of medicinal plants to treat MSG-induced obesity is an understudied…”
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Reactive oxygen species production and antioxidant enzyme activity during epididymal sperm maturation in Corynorhinus mexicanus bats
Published in Reproductive biology (01-03-2016)“…Abstract Prolonged sperm storage in the epididymis of Corynorhinus mexicanus bats after testicular regression has been associated with epididymal sperm…”
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Contribution of senescent and reactive astrocytes on central nervous system inflammaging
Published in Biogerontology (Dordrecht) (01-02-2022)“…Astrocytes, the most predominant cells in the central nervous system (CNS), have well-recognized neuroprotective functions. However, during the CNS aging,…”
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Cytokine profiling in senescent and reactive astrocytes: A systematic review
Published in Neurobiology of aging (01-06-2024)“…Astrocytes play an important role in neuroinflammation by producing proinflammatory molecules. In response to various stressful stimuli, astrocytes can become…”
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Sulforaphane - role in aging and neurodegeneration
Published in GeroScience (01-10-2019)“…In the last several years, numerous molecules derived from plants and vegetables have been tested for their antioxidant, anti-inflammatory, and anti-aging…”
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Oxidative stress-induced gene expression changes in prostate epithelial cells in vitro reveal a robust signature of normal prostatic senescence and aging
Published in Biogerontology (Dordrecht) (01-11-2024)“…Oxidative stress has long been postulated to play an essential role in aging mechanisms, and numerous forms of molecular damage associated with oxidative…”
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Health-related quality of life among Jewish older persons in Mexico and its determinants
Published in Health and quality of life outcomes (25-05-2020)“…Aging research in Mexico has significantly increased in the past decades, however, little is known on health related quality of life (HRQoL) of older adults…”
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Bcl-2 protects against oxidative stress while inducing premature senescence
Published in Free radical biology & medicine (01-04-2006)“…Replicative senescence is a cellular response to stress that has been postulated to serve as a tumor suppression mechanism and a contributor to aging. Numerous…”
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Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts
Published in Aging cell (01-12-2013)“…Summary Coordinated expression of mitochondrial and nuclear genes is required to maintain proper mitochondrial function. However, the precise mechanisms that…”
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Increased CD47 and MHC Class I Inhibitory Signals Expression in Senescent CD1 Primary Mouse Lung Fibroblasts
Published in International journal of molecular sciences (01-10-2021)“…Cellular senescence is more than a proliferative arrest in response to various stimuli. Senescent cells (SC) participate in several physiological processes,…”
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Baseline and post-stress seasonal changes in immunocompetence and redox state maintenance in the fishing bat Myotis vivesi
Published in PloS one (02-01-2018)“…Little is known of how the stress response varies when animals confront seasonal life-history processes. Antioxidant defenses and damage caused by oxidative…”
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Methotrexate Induces an Antioxidant Hormetic Response in Primary Rat Astrocytes
Published in Dose-response (01-07-2022)“…Neurodegenerative diseases have increased worldwide in recent years. Their relationship with oxidative stress has motivated the research to find therapies and…”
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