Search Results - "König, Angelika"
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Misdirection of endosomal trafficking mediated by herpes simplex virus–encoded glycoprotein B
Published in The FASEB journal (01-04-2017)“…Herpes simplex virus (HSV)–encoded glycoprotein B (gB) is the most abundant protein in the viral envelope and promotes fusion of the virus with the cellular…”
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A Novel Family of Human Leukocyte Antigen Class II Receptors May Have Its Origin in Archaic Human Species
Published in The Journal of biological chemistry (10-01-2014)“…HLA class II α and β chains form receptors for antigen presentation to CD4+ T cells. Numerous pairings of class II α and β subunits from the wide range of…”
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Stoichiometry of HLA class II-invariant chain oligomers
Published in PloS one (22-02-2011)“…The HLA gene complex encodes three class II isotypes, DR, DQ, and DP. HLA class II molecules are peptide receptors that present antigens for recognition by T…”
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4
Detection of aberrant association of DM with MHC class II subunits in the absence of invariant chain
Published in International immunology (01-01-2007)“…Human HLA-DM or mouse H2-DM plays a vital role for presentation of antigenic sequences by MHC class II peptide receptors. These non-classical MHC class II…”
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5
Invariant chains with the class II binding site replaced by a sequence from influenza virus matrix protein constrain low-affinity sequences to MHC II presentation
Published in International immunology (01-11-2000)“…Presentation of antigenic peptides by MHC II molecules is required to initiate CD4 Th cell responses. Some peptides, however, because of low affinity for MHC…”
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TOR signaling regulates liquid phase separation of the SMN complex governing snRNP biogenesis
Published in Cell reports (Cambridge) (22-06-2021)“…The activity of the SMN complex in promoting the assembly of pre-mRNA processing UsnRNPs correlates with condensation of the complex in nuclear Cajal bodies…”
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Thyroglobulin type-I-like domains in invariant chain fusion proteins mediate resistance to cathepsin L digestion
Published in FEBS letters (17-11-2000)“…The MHCII associated invariant chain isoform Ii41 shows homology to a repeat in thyroglobulin (TgR). We show that the Ii31 isoform, which lacks the TgR-like…”
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