Search Results - "Könemann, Stephanie"

Endothelin-1 influences mechanical properties and contractility of hiPSC derived cardiomyocytes resulting in diastolic dysfunction by Redwanz, Caterina, Pires, Ricardo H., Biedenweg, Doreen, Groß, Stefan, Otto, Oliver, Könemann, Stephanie

“…A better understanding of the underlying pathomechanisms of diastolic dysfunction is crucial for the development of targeted therapeutic options with the aim…”
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Promise of Blood-and Bone Marrow-Derived Stem Cell Transplantation for Functional Cardiac Repair : Putting It in Perspective With Existing Therapy by REFFELMANN, Thorsten, KÖNEMANN, Stephanie, KLONER, Robert A

“…Intracoronary transplantation of peripheral blood- or bone marrow-derived cells, as tested in several recent trials, is associated with moderate increases in…”
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Preliminary results of the cross-sectional associations of sedentary behavior and physical activity with serum brain-derived neurotrophic factor in adults with coronary heart disease by Ullrich, Antje, Wenzel, Kristin, Bahls, Martin, Voigt, Lisa, Könemann, Stephanie, Dörr, Marcus, Wurm, Susanne, Ulbricht, Sabina

“…This is the first study to analyze the association of accelerometer-measured patterns of habitual physical activity (PA) and sedentary behavior (SB) with serum…”
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Simultaneous assessment of spontaneous cage activity and voluntary wheel running in group-housed mice by Reuser, Annika, Wenzel, Kristin, Felix, Stephan B., Dörr, Marcus, Bahls, Martin, Könemann, Stephanie

“…Small animal models are frequently used to improve our understanding of the molecular and biological signaling pathways underlying the beneficial effects of…”
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Publisher Correction: Simultaneous assessment of spontaneous cage activity and voluntary wheel running in group-housed mice by Reuser, Annika, Wenzel, Kristin, Felix, Stephan B., Dörr, Marcus, Bahls, Martin, Könemann, Stephanie

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A Transgenic Mouse Model of Eccentric Left Ventricular Hypertrophy With Preserved Ejection Fraction Exhibits Alterations in the Autophagy-Lysosomal Pathway by Wenzel, Kristin, Krämer, Elisabeth, Geertz, Birgit, Carrier, Lucie, Felix, Stephan B, Könemann, Stephanie, Schlossarek, Saskia

“…The ubiquitin-proteasome system (UPS) and the autophagy-lysosomal pathway (ALP) are the main proteolytic systems involved in cellular homeostasis. Since…”
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Crataegus Extract WS®1442 Stimulates Cardiomyogenesis and Angiogenesis From Stem Cells: A Possible New Pharmacology for Hawthorn? by Halver, Jonas, Wenzel, Kristin, Sendker, Jandirk, Carrillo García, Carmen, Erdelmeier, Clemens A J, Willems, Erik, Mercola, Mark, Symma, Nico, Könemann, Stephanie, Koch, Egon, Hensel, Andreas, Schade, Dennis

“…Extracts from the leaves and flowers of spp. (i.e., hawthorn species) have been traditionally used with documented preclinical and clinical activities in…”
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Sacubitril/valsartan reduces proteasome activation and cardiomyocyte area in an experimental mouse model of hypertrophy by Meyer-Jens, Moritz, Wenzel, Kristin, Grube, Karina, Rüdebusch, Julia, Krämer, Elisabeth, Bahls, Martin, Müller, Kilian, Voß, Hannah, Schlüter, Hartmut, Felix, Stephan B., Carrier, Lucie, Könemann, Stephanie, Schlossarek, Saskia

“…Sacubitril/valsartan (Sac/Val) belongs to the group of angiotensin receptor–neprilysin inhibitors and has been used for the treatment of heart failure (HF) for…”
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The Other Side of the RAAS: Aldosterone Improves Migration of Cardiac Progenitor Cells by Könemann, Stephanie, Wenzel, Kristin, Ameling, Sabine, Grube, Karina, Hammer, Elke, Könemann, Raik, Samal, Rasmita, Völker, Uwe, Felix, Stephan B.

“…Stem cell therapy is a promising new option for patients suffering from heart failure. Though many clinical studies show encouraging results, little is known…”
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Brain derived neurotrophic factor contributes to the cardiogenic potential of adult resident progenitor cells in failing murine heart by Samal, Rasmita, Ameling, Sabine, Dhople, Vishnu, Sappa, Praveen Kumar, Wenzel, Kristin, Völker, Uwe, Felix, Stephan B, Hammer, Elke, Könemann, Stephanie

“…Resident cardiac progenitor cells show homing properties when injected into the injured but not to the healthy myocardium. The molecular background behind this…”
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Sex-Specific Associations of Brain-Derived Neurotrophic Factor and Cardiorespiratory Fitness in the General Population by Schmalhofer, Marie-Lena, Markus, Marcello R P, Gras, Jan C, Kopp, Juliane, Janowitz, Deborah, Grabe, Hans-Jörgen, Groß, Stefan, Ewert, Ralf, Gläser, Sven, Albrecht, Diana, Eiffler, Ina, Völzke, Henry, Friedrich, Nele, Nauck, Matthias, Steveling, Antje, Könemann, Stephanie, Wenzel, Kristin, Felix, Stephan B, Dörr, Marcus, Bahls, Martin

“…The brain-derived neurotrophic factor (BDNF) was initially considered to be neuron-specific. Meanwhile, this neurotrophin is peripherally also secreted by…”
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Promise of Blood- and Bone Marrow-Derived Stem Cell Transplantation for Functional Cardiac Repair by Reffelmann, Thorsten, MD, Könemann, Stephanie, MD, Kloner, Robert A., MD, PhD, FACC

“…Intracoronary transplantation of peripheral blood- or bone marrow-derived cells, as tested in several recent trials, is associated with moderate increases in…”
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Personalized nutritional prevention for Lp(a): PUFAs seem to do the job by Lehnert, Kristin, Könemann, Stephanie, Bahls, Martin

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The Influence of BDNF and Exercise on the Progression of Heart Failure in Mice by Reuser, Annika K., Wenzel, Kristin, Felix, Stephan B., Bahls, Martin, Könemann, Stephanie

“…Introduction Recent studies suggest that not only exercise training but also brain‐derived neurotrophic factor (BDNF) influences the progression of heart…”
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Brain-derived neurotrophic factor is related with adverse cardiac remodeling and high NTproBNP by Bahls, Martin, Könemann, Stephanie, Markus, Marcello R. P., Wenzel, Kristin, Friedrich, Nele, Nauck, Matthias, Völzke, Henry, Steveling, Antje, Janowitz, Deborah, Grabe, Hans-Jörgen, Felix, Stephan B., Dörr, Marcus

“…The brain-derived neurotrophic factor (BDNF) is a neuronal growth factor essential for normal cardiac contraction and relaxation. Alterations in BDNF signaling…”
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Cardioprotective effect of the secretome of Sca-1+ and Sca-1− cells in heart failure: not equal, but equally important? by Könemann, Stephanie, Sartori, Luiz V, Gross, Stefan, Hadlich, Stefan, Kühn, Jens-Peter, Samal, Rasmita, Bahls, Martin, Felix, Stephan B, Wenzel, Kristin

“…Abstract Aims Both progenitor and differentiated cells were previously shown to secrete cardioprotective substances, but so far there has been no direct…”
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Global secretome analysis of resident cardiac progenitor cells from wild‐type and transgenic heart failure mice: Why ambience matters by Samal, Rasmita, Sappa, Praveen Kumar, Gesell Salazar, Manuela, Wenzel, Kristin, Reinke, Yvonne, Völker, Uwe, Felix, Stephan Burkhard, Hammer, Elke, Könemann, Stephanie

“…Resident cardiac progenitor cells (CPCs) have gained attention in cardiac regenerative medicine primarily due to their paracrine activity. In our current study…”
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Analysis of DCM associated protein alterations of human right and left ventricles by Ameling, Sabine, Bischof, Julia, Dörr, Marcus, Könemann, Stephanie, Empen, Klaus, Weitmann, Kerstin, Klingel, Karin, Beug, Daniel, Dhople, Vishnu Mukund, Völker, Uwe, Hammer, Elke, Felix, Stephan B.

“…Dilated cardiomyopathy (DCM) is characterized by ventricular chamber enlargement and impaired myocardial function. Endomyocardial biopsies (EMB) enable…”
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Sugars make the difference – Glycosylation of cardiodepressant antibodies regulates their activity in dilated cardiomyopathy by Reinke, Yvonne, Könemann, Stephanie, Chamling, Bishwas, Gross, Stefan, Weitmann, Kerstin, Hoffmann, Wolfgang, Klingel, Karin, Nauck, Matthias, Fielitz, Jens, Dörr, Marcus, Felix, Stephan B.

“…Cardiodepressant antibodies contribute to cardiac dysfunction in dilated cardiomyopathy (DCM). Changes in immunoglobulin G (IgG) glycosylation modulate the…”
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Pathophysiological aldosterone levels modify the secretory activity of cardiac progenitor cells by Wenzel, Kristin, Samal, Rasmita, Hammer, Elke, Dhople, Vishnu M., Gross, Stefan, Völker, Uwe, Felix, Stephan B., Könemann, Stephanie

“…Cardiac progenitor cells (CPCs) trigger regenerative processes via paracrine mechanisms in response to changes in their environment. In the present study we…”
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