Search Results - "Kölsch, Heike"
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Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment
Published in Neurology (25-09-2012)“…OBJECTIVE:To identify biological evidence for Alzheimer disease (AD) in individuals with subjective memory impairment (SMI) and unimpaired cognitive…”
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Systemic therapy in children and adolescents with mental disorders: a systematic review and meta-analysis
Published in BMC psychiatry (14-02-2024)“…Systemic therapy (ST) is a psychotherapeutic intervention in complex human systems (both psychological and interpersonal). Cognitive behavioural therapy (CBT)…”
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3
Reporting bias in medical research - a narrative review
Published in Current controlled trials in cardiovascular medicine (13-04-2010)“…Reporting bias represents a major problem in the assessment of health care interventions. Several prominent cases have been described in the literature, for…”
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Identification of the Genetic Basis for Complex Disorders by Use of Pooling-Based Genomewide Single-Nucleotide–Polymorphism Association Studies
Published in American journal of human genetics (01-01-2007)“…We report the development and validation of experimental methods, study designs, and analysis software for pooling-based genomewide association (GWA) studies…”
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Capillary cerebral amyloid angiopathy identifies a distinct APOE ε4-associated subtype of sporadic Alzheimer’s disease
Published in Acta neuropathologica (01-08-2010)“…The deposition of amyloid β-protein (Aβ) in the vessel wall, i.e., cerebral amyloid angiopathy (CAA), is associated with Alzheimer’s disease (AD). Two types of…”
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Alterations of cholesterol precursor levels in Alzheimer's disease
Published in Biochimica et biophysica acta (01-08-2010)“…Cerebral and extracerebral cholesterol metabolism are altered in Alzheimer's disease (AD) as indicated by reduced plasma levels of the cholesterol elimination…”
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Macrophage migration inhibitory factor in mild cognitive impairment and Alzheimer’s disease
Published in Journal of psychiatric research (01-05-2009)“…Abstract Inflammatory processes may substantially contribute to the cerebral pathology in Alzheimer’s disease (AD) and accelerate the disease progression. The…”
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CSF cortisol in Alzheimer's disease and mild cognitive impairment
Published in Neurobiology of aging (01-03-2009)“…Abstract Hypercortisolaemia occurs in Alzheimer's disease (AD) and may be involved in the AD related neurodegenerative process. In order to determine whether…”
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Genome-Wide Association Study of Vascular Dementia
Published in Stroke (1970) (01-02-2012)“…Most studies investigating the genetics of dementia have focused on Alzheimer disease, but little is known about the genetics of vascular dementia. The aim of…”
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The power of sample size and homogenous sampling: Association between the 5-HTTLPR serotonin transporter polymorphism and major depressive disorder
Published in Biological psychiatry (1969) (01-02-2005)“…Several lines of evidence indicate that abnormalities in the functioning of the central serotonergic system are involved in the pathogenesis of affective…”
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Cerebral and extracerebral cholesterol metabolism and CSF markers of Alzheimer's disease
Published in Biochemical pharmacology (01-07-2013)“…Biosynthesis of cholesterol: from lanosterol to cholesterol, and the conversion to 24S- and 27-hydroxycholesterol 24 DHCR=24-dehydrocholesterol reductase; Cyp…”
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Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease
Published in Journal of neuroinflammation (23-08-2009)“…Chronic inflammation is a characteristic of Alzheimer's disease (AD). An interaction associated with the risk of AD has been reported between polymorphisms in…”
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Association of the glutathione S-transferase omega-1 Ala140Asp polymorphism with cerebrovascular atherosclerosis and plaque-associated interleukin-1 alpha expression
Published in Stroke (1970) (01-10-2007)“…Glutathione S-transferase omega-1 is a multifunctional enzyme. The Asp/Asp genotype of the Ala140Asp polymorphism of the GSTO1 gene has been alleged to…”
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14
RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism
Published in Journal of cellular and molecular medicine (01-03-2009)“…Cholesterol metabolism is altered in Alzheimer's disease (AD). The nuclear hormone receptor Retinoic X Receptor a (RXRa) is a member of the nuclear…”
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Negative pressure wound therapy in patients with wounds healing by secondary intention: a systematic review and meta-analysis of randomised controlled trials
Published in Systematic reviews (10-10-2020)“…Negative pressure wound therapy (NPWT) is a widely used method of wound treatment. We performed a systematic review of randomised controlled trials (RCTs)…”
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The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells
Published in Brain research (06-02-1999)“…Neurodegenerative disorders are characterized by a massive loss of nerve cells. The neuronal cell death is accompanied by an increased cholesterol release and…”
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Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease
Published in Journal of neurochemistry (01-10-2012)“…Disturbances of the cholesterol metabolism are associated with Alzheimer's disease (AD) risk and related cerebral pathology. Experimental studies found…”
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Polymorphism in the BACE gene influences the risk for Alzheimer's disease
Published in Neuroreport (01-07-2003)“…Pathological characteristics of Alzheimer's disease (AD) are neurofibrillary tangles and amyloid-β (Aβ) plaques. Aβ is generated by cleavage of the amyloid…”
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Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project
Published in Neurobiology of aging (2012)“…Abstract Iron overload may contribute to the risk of Alzheimer's disease (AD). In the Epistasis Project, with 1757 cases of AD and 6295 controls, we studied 4…”
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Noradrenergic Modulation of Emotion-Induced Forgetting and Remembering
Published in The Journal of neuroscience (06-07-2005)“…We used a free-recall paradigm to establish a behavioral index of the retrograde and anterograde interference of emotion with episodic memory encoding. In two…”
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