Search Results - "Kölsch, H"

Interaction effects of subjective memory impairment and ApoE4 genotype on episodic memory and hippocampal volume by Striepens, N, Scheef, L, Wind, A, Meiberth, D, Popp, J, Spottke, A, Kölsch, H, Wagner, M, Jessen, F

“…The apolipoprotein E4 allele (ApoE4) is an established genetic risk factor for Alzheimer's disease (AD). However, its effects on cognitive performance and…”
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The plant sterol brassicasterol as additional CSF biomarker in Alzheimer's disease by Vanmierlo, T., Popp, J., Kölsch, H., Friedrichs, S., Jessen, F., Stoffel-Wagner, B., Bertsch, T., Hartmann, T., Maier, W., von Bergmann, K., Steinbusch, H., Mulder, M., Lütjohann, D.

“…Vanmierlo T, Popp J, Kölsch H, Friedrichs S, Jessen F, Stoffel‐Wagner B, Bertsch T, Hartmann T, Maier W, von Bergmann K, Steinbusch H, Mulder M, Lütjohann D…”
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Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients by Kölsch, H., Heun, R., Kerksiek, A., Bergmann, K.v., Maier, W., Lütjohann, D.

“…Alterations in brain cholesterol metabolism and reduced 24S-hydroxycholesterol plasma levels have been described in Alzheimer’s disease (AD) and vascular…”
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A multicenter (1)H-MRS study of the medial temporal lobe in AD and MCI by Jessen, F, Gür, O, Block, W, Ende, G, Frölich, L, Hammen, T, Wiltfang, J, Kucinski, T, Jahn, H, Heun, R, Maier, W, Kölsch, H, Kornhuber, J, Träber, F

“…The need for biological markers of Alzheimer disease (AD) is constantly increasing. Proton magnetic resonance spectroscopy ((1)H-MRS) studies have provided…”
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Effects of estrogen on brain development and neuroprotection—implications for negative symptoms in schizophrenia by Rao, M.L., Kölsch, H.

“…Increasing evidence during the last few years suggests that there are gender-specific differences in schizophrenia, influencing the age of onset, treatment…”
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Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke by KÖLSCH, H, LINNEBANK, M, VON BERGMANN, K, MAIER, W, HEUN, R, LÜTJOHANN, D, JESSEN, F, WÜLLNER, U, HARBRECHT, U, THELEN, K. M, KREIS, M, HENTSCHEL, F, SCHULZ, A

“…Glutathione S-transferase omega-1 (GSTO1) protects from oxidative stress, a risk factor for Alzheimer disease (AD), vascular dementia (VaD), and stroke…”
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ACE I/D polymorphism is a risk factor of Alzheimer's disease but not of vascular dementia by Kölsch, H., Jessen, F., Freymann, N., Kreis, M., Hentschel, F., Maier, W., Heun, R.

“…Different studies have investigated the effect of the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism on the risk of Alzheimer…”
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Risk factors and early signs of Alzheimer's disease in a family study sample. Risk of AD by Heun, Reinhard, Kölsch, Heike, Jessen, Frank

“…Several predictors of Alzheimer's disease (AD) have been identified. However, the relevance and independent contribution of risk factors and of possible early…”
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Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease by KÖLSCH, H, LÜTJOHANN, D, LUDWIG, M, SCHULTE, A, PTOK, U, JESSEN, F, VON BERGMANN, K, RAO, M. L, MAIER, W, HEUN, R

“…Cholesterol and 24S-hydroxycholesterol are involved in the pathogenesis of Alzheimer's disease (AD). Increased serum cholesterol concentrations have been…”
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The variant methylenetetrahydrofolate reductase c.1298A > C (p.E429A) is associated with multiple sclerosis in a German case-control study by Klotz, L., Farkas, M., Bain, N., Keskitalo, S., Semmler, A., Ineichen, B., Jelcic, J., Klockgether, T., Kölsch, H., Weller, M., Linnebank, M.

“…Multiple sclerosis (MS) is an inflammatory demyelinating autoimmune disease of the central nervous system. We investigated the association of two missense…”
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Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17β by KÖLSCH, H, LUDWIG, M, LÜTJOHANN, D, RAO, M. L

“…24-Hydroxycholesterol, the main cholesterol elimination product of the brain is increased in serum of Alzheimer patients. This oxysterol behaves neurotoxic…”
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The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma by LINNEBANK, M, SCHMIDT, S, PELS, H, KÖLSCH, H, LINNEBANK, A, HEUN, R, SCHMIDT-WOLF, I. G. H, GLASMACHER, A, FLIESSBACH, K, KLOCKGETHER, T, SCHLEGEL, U

“…Primary central nervous system lymphomas (PCNSL) frequently reveal genomic instability. We analysed different functional genetic variants affecting the folate…”
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Gene variations in GSTM3 are a risk factor for Alzheimer's disease by Hong, G.-S, Heun, R, Jessen, F, Popp, J, Hentschel, F, Kelemen, P, Schulz, A, Maier, W, Kölsch, H

“…Abstract Oxidative stress is a relevant pathomechanism in Alzheimer's disease (AD) and gene variations in the glutathione S-transferase M3 gene (GSTM3),…”
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Influence of peroxisome proliferator-activated receptor gamma gene polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients by Sauder, S, Kölsch, H, Lütjohann, D, Schulz, A, von Bergmann, K, Maier, W, Heun, R

“…The peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear hormone receptor, that is involved in lipid and glucose metabolism, which both…”
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Pharmacokinetics of m-chlorophenylpiperazine after intravenous and oral administration in healthy male volunteers: implication for the pharmacodynamic profile by Feuchtl, A, Bagli, M, Stephan, R, Frahnert, C, Kölsch, H, Kühn, K U, Rao, M L

“…Serotonin plays an important role in psychiatric diseases, most notably in depression and anxiety. Seven different major serotonin receptor subtypes have been…”
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Association of CETP polymorphisms with the risk of vascular dementia and white matter lesions by Qureischie, H., Heun, R., Popp, J., Jessen, F., Maier, W., Schmitz, S., Hentschel, F., Kelemen, P., Kölsch, H.

“…Cholesteryl ester transfer protein (CETP), a component of the high density lipoprotein (HDL), plays a central role in reverse cholesterol transport. We…”
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Polymorphism in the peroxisome proliferator-activated receptor α gene influences the risk for Alzheimer's disease by BRUNE, S, KÖLSCH, H, PTOK, U, MAJORES, M, SCHULZ, A, SCHLOSSER, R, RAO, M. L, MAIER, W, HEUN, R

“…The peroxisome proliferator-activated receptor alpha (PPAR-alpha) is a member of the steroid hormone super family of ligand-inducible transcription factors,…”
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G.P.15.10 Screening for signs of myopathy associated with drugs of abuse and hepatitis C infection in patients admitted for detoxification treatment by Reimann, J, Kölsch, H, Schütz, C.G

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Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study by Lewczuk, P, Kamrowski-Kruck, H, Peters, O, Heuser, I, Jessen, F, Popp, J, Bürger, K, Hampel, H, Frölich, L, Wolf, S, Prinz, B, Jahn, H, Luckhaus, Ch, Perneczky, R, Hüll, M, Schröder, J, Kessler, H, Pantel, J, Gertz, H-J, Klafki, H-W, Kölsch, H, Reulbach, U, Esselmann, H, Maler, J M, Bibl, M, Kornhuber, J, Wiltfang, J

“…In this report, we present the results of a multicenter study to test analytic and diagnostic performance of soluble forms of amyloid precursor proteins α and…”
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Common genetic variants of homocysteine metabolism in ischemic stroke: a case-control study by Linnebank, M., Montenarh, M., Kölsch, H., Linnebank, A., Schnez, K., Schweichel, D., Pohl, C., Urbach, H., Heun, R., Harbrecht, U., Klockgether, T., Wüllner, U.

“…Hyperhomocysteinemia is a risk factor for ischemic stroke. We investigated five functional polymorphisms involved in homocysteine metabolism in each 159 stroke…”
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