Search Results - "Kökbudak, Zülbiye"

Investigation of structural, electronical and in vitro cytotoxic activity properties of some heterocyclic compounds by Akkoç, Senem, Tüzün, Burak, Özalp, Ayhan, Kökbudak, Zülbiye

“…•Some compounds were synthesized and characterized.•All molecules were screened against human cancer cell lines, and a compound showed promising…”
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Drug design of new therapeutic agents: molecular docking, molecular dynamics simulation, DFT and POM analyses of new Schiff base ligands and impact of substituents on bioactivity of their potential antifungal pharmacophore site by Akkoc, Senem, Karatas, Halis, Muhammed, Muhammed Tilahun, Kökbudak, Zülbiye, Ceylan, Ahmet, Almalki, Faisal, Laaroussi, Hamid, Ben Hadda, Taibi

“…Since Schiff base derivatives have a wide range of biological activities, novel Schiff base derivatives were designed and synthesized in satisfactory yields. 1…”
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Anticancer activities of various new metal complexes prepared from a Schiff base on A549 cell line by Aslan, Halime Güzin, Akkoç, Senem, Kökbudak, Zülbiye

“…[Display omitted] •Eight new metal complexes were synthesized and characterized.•All compounds (S3–S10) were screened against A549 cell line.•S3–S10 had…”
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Determination of the interactions of a schiff base with different targets via molecular docking and cytotoxic activity studies by Türkmenoğlu, Burçin, Bayar, İrem, Kökbudak, Zülbiye, Akkoc, Senem

“…The pyrimidine nucleus is a vital pharmacophore that exhibits excellent pharmacological activity. A Schiff base containing a pyrimidine nucleus was obtained in…”
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Experimental and theoretical studies on 3-(4-chlorophenyl)-5-(4-ethoxyphenyl)-4,5-dihydropyrazole-1-carbonitrile: DFT quantum mechanical calculation, vibrational band analysis, prediction of activity spectra, and molecular docking by Zeyrek, Celal Tuğrul, Akman, Soner, Ilhan, Ilhan Ozer, Kökbudak, Zülbiye, Sarıpınar, Emin, Akkoc, Senem

“…•A new compound was synthesized and fully characterized.•Theoretical calculations of compound were done.•PASS analysis of compound was implemented Synthesis,…”
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Synthesis, cytotoxic activity and quantum chemical calculations of new 7-thioxopyrazolo[1,5-f]pyrimidin-2-one derivatives by Kökbudak, Zülbiye, Saracoglu, Murat, Akkoç, Senem, Çimen, Zeynep, Yilmazer, M. Izzettin, Kandemirli, Fatma

“…The reactions of 1-amino-2-thioxo-1,2-dihydropyrimidin derivatives 1 and 2 with chloroacetyl chloride in the presence of sodium acetate led to the formation of…”
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Design, synthesis, in vitro antiproliferative activity properties, quantum chemical and molecular docking studies of novel Schiff bases incorporating pyrimidine nucleus by Devim, Mahmut, Akkoç, Senem, Zeyrek, Celal Tuğrul, Aslan, Halime Güzin, Kökbudak, Zülbiye

“…•A series of new compounds were synthesized and fully characterized.•In vitro cytotoxic activities of these compounds were tested against human cell lines.•The…”
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The crystal structure of 5-benzoyl-1-[(E)-(4-fluorobenzylidene)amino]-4-phenylpyrimidin-2(1H)-one, C24H16FN3O2 by Atioğlu, Zeliha, Karataş, Halis, Kökbudak, Zülbiye

“…FN , monoclinic, (no. 4),  = 6.0024(5) Å,  = 19.474(2) Å,  = 8.3531(8) Å,  = 91.750(9)°,  = 975.95(16) Å ,  = 2, ) = 0.0409, ) = 0.0832, T = 294(2) K…”
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Novel Quinoline-Based Thiosemicarbazide Derivatives: Synthesis, DFT Calculations, and Investigation of Antitubercular, Antibacterial, and Antifungal Activities by Özcan, Esma, Vagolu, Siva Krishna, Gündüz, Miyase Gözde, Stevanovic, Milena, Kökbudak, Zülbiye, Tønjum, Tone, Nikodinovic-Runic, Jasmina, Çetinkaya, Yasin, Doğan, Şengül Dilem

“…The discovery of new antimicrobial agents as a means of treating drug-resistant microbial pathogens is of utmost significance to overcome their immense risk to…”
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New Schiff Bases Based on 1-Aminopyrimidin-2-(1H)-one: Design, Synthesis, Characterization and Theoretical Calculations by Akkoç, Senem, Kökbudak, Zülbiye, Güzin Aslan, Halime

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Synthesis, characterization, and antimicrobial and catalytic activity of a new Schiff base and its metal(II) complexes by Aslan, Halime Güzin, Akkoç, Senem, Kökbudak, Zülbiye, Aydın, Lütfiye

“…We presented the synthesis of a new Schiff base and its complexes properties with some transition metal ions in this study…”
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In Silico and In Vitro Antiproliferative Activity Assessment of New Schiff Bases by Kökbudak, Zülbiye, Akkoç, Senem, Karataş, Halis, Tüzün, Burak, Aslan, Güzin

“…In this study, a series of new Schiff bases, based on a pyrimidine core, were synthesized in two steps. The structures of these newly synthesized Schiff bases…”
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Cytotoxic activities of the pyrimidine-based acetamide and isophthalimide derivatives: an in vitro and in silico studies by Muhammed, Muhammed Tilahun, Kokbudak, Zülbiye, Akkoc, Senem

“…In here, a series of pyrimidin-(1(2H)-yl)acetamide and pyrimidin-(1(2H)-yl)isophthalimide derivatives were synthesised according to literature. The cytotoxic…”
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Corrosion inhibition of mild steel in acidic media using new oxo-pyrimidine derivatives: Experimental and theoretical insights by Ferigita, Khaled Saad Miled, Saracoglu, Murat, AlFalah, Mothana Ghazi Kadhim, Yilmazer, Mehmet Izzettin, Kokbudak, Zülbiye, Kaya, Savaş, Kandemirli, Fatma

“…•These the compounds are 1-(5-(4-Methoxy-benzoyl)−4-(4‑methoxy-phenyl)−2-oxo-2H-pyrimidin-1-yl]-(4‑methoxy-phenyl)-urea (MMOM) and…”
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Corrosion behaviour of new oxo-pyrimidine derivatives on mild steel in acidic media: Experimental, surface characterization, theoretical, and Monte Carlo studies by Ferigita, Khaled Saad Miled, AlFalah, Mothana Ghazi Kadhim, Saracoglu, Murat, Kokbudak, Zülbiye, Kaya, Savaş, Alaghani, Muna Omar Abdels, Kandemirli, Fatma

“…In this work, the effects of new compounds, namely, 1-amino-5-(4-methylbenzoyl)-4-(4-methylphenyl) pyrimidin-2 (1H)-thione (AMMP), and…”
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The crystal structure of 5-benzoyl-1-[( E )-(4-fluorobenzylidene)amino]-4-phenylpyrimidin-2(1 H )-one, C 24 H 16 FN 3 O 2 by Atioğlu, Zeliha, Karataş, Halis, Kökbudak, Zülbiye

“…C 24 H 16 FN 3 O 2 , monoclinic, P 2 1 (no. 4), a  = 6.0024(5) Å, b  = 19.474(2) Å, c  = 8.3531(8) Å, β  = 91.750(9)°, V  = 975.95(16) Å 3 , Z  = 2, R gt ( F…”
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Schiff base derivatives against monkeypox virus: Synthesis, in silico, MM-GBSA and SAR properties by Karataş, Halis, Kiliç, Hülya Kübra, Tüzün, Burak, Kökbudak, Zülbiye

“…•A pyrimidine-doped schiff base, was synthesized in this study.•Its effect on the activity was investigated by connecting various functional groups with the…”
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N -[2-(Benzylideneamino)phenyl]- N ′-phenylurea by Atioğlu, Zeliha, Buran, Sümeyye, Doğan, Dilem, Kökbudak, Zülbiye, Aygün, Muhittin, Akkurt, Mehmet

“…In the title compound, C 20 H 17 N 3 O [systematic name: 1-phenyl-3-{2-[( E )- (phenylmethylidene)amino]phenyl}urea], the middle benzene ring forms dihedral…”
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Could pyrimidine derivative be effective against Omicron of SARS-CoV-2? by Karatas, Halis, Tuzun, Burak, Kokbudak, Zulbiye

“…BACKGROUNDA pyrimidine based Schiff base was examined in this report. Structural and spectral characterizations were done with Gaussian software. Active sites…”
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Antiquorum Sensing Effect, Theoretical, and X‐Ray Studies of a Schiff Base Molecule Containing Pyrimidine Nucleus by Karatas, Halis, Onem, Ebru, Akkoc, Senem, Tuğrul Zeyrek, Celal, Sibel Sahin, Zarife, Kokbudak, Zülbiye

“…Compound 4, a Schiff base‐containing pyrimidine moiety, was synthesized from the reaction of N‐amino pyrimidine derivative with 4‐fluorobenzaldehyde. The…”
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