Search Results - "Köger, Nicole"

ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer by Richter, Antje M, Kiehl, Steffen, Köger, Nicole, Breuer, Janina, Stiewe, Thorsten, Dammann, Reinhard H

“…Lung cancer is the leading cause of cancer-related deaths with 1.8 million new cases each year and poor 5-year prognosis. Promoter hypermethylation of tumour…”
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Exome sequencing identifies MUTYH mutations in a family with colorectal cancer and an atypical phenotype by Seguí, Nuria, Navarro, Matilde, Pineda, Marta, Köger, Nicole, Bellido, Fernando, González, Sara, Campos, Olga, Iglesias, Silvia, Valdés-Mas, Rafael, López-Doriga, Adriana, Gut, Marta, Blanco, Ignacio, Lázaro, Conxi, Capellá, Gabriel, Puente, Xose S, Plotz, Guido, Valle, Laura

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Functional testing strategy for coding genetic variants of unclear significance in MLH1 in Lynch syndrome diagnosis by Hinrichsen, Inga, Schäfer, Dieter, Langer, Deborah, Köger, Nicole, Wittmann, Margarethe, Aretz, Stefan, Steinke, Verena, Holzapfel, Stefanie, Trojan, Jörg, König, Rainer, Zeuzem, Stefan, Brieger, Angela, Plotz, Guido

“…Lynch syndrome is caused by inactivating mutations in the MLH1 gene, but genetic variants of unclear significance frequently preclude diagnosis. Functional…”
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Analysis of MUTYH alternative transcript expression, promoter function, and the effect of human genetic variants by Köger, Nicole, Brieger, Angela, Hinrichsen, Inga M., Zeuzem, Stefan, Plotz, Guido

“…The human DNA repair gene MUTYH, whose mutational loss causes a colorectal polyposis and cancer predisposition, contains three alternative first exons. In…”
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Evaluation of MLH1 variants of unclear significance by Köger, Nicole, Paulsen, Lea, López-Kostner, Francisco, Della Valle, Adriana, Vaccaro, Carlos Alberto, Palmero, Edenir Inêz, Alvarez, Karin, Sarroca, Carlos, Neffa, Florencia, Kalfayan, Pablo German, Gonzalez, Maria Laura, Rossi, Benedito Mauro, Reis, R. M., Brieger, Angela, Zeuzem, Stefan, Hinrichsen, Inga, Dominguez-Valentin, Mev, Plotz, Guido

“…Inactivating mutations in the MLH1 gene cause the cancer predisposition Lynch syndrome, but for small coding genetic variants it is mostly unclear if they are…”
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